Toward Sustainable Polyhydroxyalkanoates: A Next-Gen Biotechnology Approach
Polymers,
Год журнала:
2025,
Номер
17(7), С. 853 - 853
Опубликована: Март 22, 2025
Polyhydroxyalkanoates
(PHAs)
are
biodegradable
biopolymers
synthesized
by
microorganisms
and
serve
as
sustainable
alternatives
to
petroleum-based
plastics.
While
traditional
PHA
production
relies
on
refined
carbon
sources
pure
cultures,
high
costs
scalability
challenges
limit
commercial
viability.
Extremophiles,
particularly
halophiles,
have
emerged
promising
candidates
for
cost-effective,
large-scale
of
PHAs.
Their
ability
thrive
in
extreme
environments
reduces
contamination
risks,
minimizes
the
need
sterilization,
lowers
operational
costs.
Advancements
metabolic
engineering,
synthetic
biology,
CRISPR-based
genome
editing
enhanced
yields
optimizing
flux
cell
morphology.
Additionally,
utilizing
alternative
feedstocks
such
biowaste,
syngas,
methane,
CO₂
improves
economic
feasibility.
Next-generation
industrial
biotechnology
integrates
extremophilic
microbes
with
AI-driven
fermentation
eco-friendly
downstream
processing
enhance
scalability.
Industrial-scale
PHAs
using
Halomonas
spp.
other
extremophiles
demonstrates
significant
progress
toward
commercialization,
paving
way
biopolymer
applications
reducing
plastic
pollution.
Язык: Английский
Production of polyhydroxyalkanoate (PHA) biopolymer from crop residue using bacteria as an alternative to plastics: a review
RSC Advances,
Год журнала:
2025,
Номер
15(15), С. 11845 - 11862
Опубликована: Янв. 1, 2025
Production
of
polyhydroxyalkanoate
(PHA)
biopolymer
from
crop
residue
using
microbial
strain.
Язык: Английский