Air Quality Atmosphere & Health,
Год журнала:
2024,
Номер
unknown
Опубликована: Апрель 3, 2024
Abstract
The
purposes
of
this
study
were
to
evaluate
the
bulk
sample
concentration
and
airborne
concentrations
phthalate
in
different
types
propellent
triggers
consumer
spray
products
estimate
health
risk
assessment
via
inhalation.
First,
analyzed
solutions
all
174
from
markets.
Then,
among
64
containing
phthalates,
10
propellant-type
selected
that
contained
high
concentrations;
measured
at
distances
1,
3,
5
m
nozzle
a
clean
room.
Four
phthalates
detected
products:
diisobutyl
(DiBP),
di-n-butyl
(DnBP),
butyl
benzyl
(BBzP),
bis(2-ethylhexyl)
(DEHP).
Among
products,
repellents
highest
mean
(3.90
ppm),
whereas
sterilized
lowest
(0.59
ppm).
trigger-type
cleaning
(4.54
coating
(0.73
In
both
propellant-
DnBP
DEHP
exceeded
standard
set
by
Ministry
Food
Drug
Safety
South
Korea.
No
significant
patterns
observed
for
DiBP,
DnBP,
(p
>
0.05).
Children
one
population
groups
most
susceptible
risks.
Overall,
product
air
products;
some
even
safe
limits.
Therefore,
should
be
used
well-ventilated
areas
avoid
respiratory
exposure.
Nutrients,
Год журнала:
2024,
Номер
16(18), С. 3213 - 3213
Опубликована: Сен. 23, 2024
Background:
Phenylketonuria
(PKU)
is
the
most
common
amino
acid
metabolism
disorder.
Patients
with
blood
phenylalanine
(Phe)
levels
of
≥6
mg/dL
require
treatment,
and
definitive
treatment
Phe-restricted
diet.
Bisphenols
phthalates
are
widely
used
endocrine-disrupting
chemicals
(EDCs)
found
in
personal
care
products,
baby
bottles,
food
packaging.
Methods:
In
this
study,
we
evaluated
possible
routes
exposure
to
these
EDCs
patients
diagnosed
PKU
(n
=
105,
2–6
years
age)
determined
relationship
between
plasma
bisphenol
A
(BPA),
F
(BPF),
di-butyl
phthalate
(DBP),
di-(2-ethylhexyl)
(DEHP),
mono-(2ethylhexyl)
(MEHP),
dietary
regimens.
Participant
characteristics
were
according
their
status.
Results:
Thirty-four
on
a
diet,
while
remaining
71
had
no
restrictions.
DBP
DEHP
higher
those
using
plastic
tablecloths
(p
0.049
p
0.04,
respectively).
addition,
who
bottled
water
0.01).
Being
under
4
age,
containers,
shower
curtains
associated
MEHP
0.027,
0.019,
0.014,
After
adjustment
for
baseline
(Model
1),
odds
having
BPA
level
upper
tertile
3.34
times
free-diet
group
(95%
CI
1.09–10.25).
When
additionally
adjusted
2),
ratio
was
be
18.64
2.09–166.42)
BPA.
group,
probability
increased
by
relative
risk
3.01
0.039,
95%
1.06–8.60).
Conclusion:
Our
results
indicate
that
bisphenols
varies
treatment.
The
difference
sources
diet
non-diet
groups
indicates
plays
an
important
role
EDC
exposure.
Frontiers in Marine Science,
Год журнала:
2024,
Номер
11
Опубликована: Март 12, 2024
Plastic
additives
include
a
wide
range
of
pollutants,
added
throughout
the
production
process
plastics
aiming
to
improve
their
properties.
Given
that
they
are
not
chemically
bound
plastic
items,
can
easily
migrate
in
marine
environment
allowing
uptake
by
organisms
and
accumulation
tissues.
Representatives
Phthalic
acid
esters
(PAEs)
bisphenols
have
been
characterized
for
ability
impact
only
but
also
humans
via
fish
seafood
consumption.
In
this
study,
liquid-liquid
method
was
applied
determine
concentrations
selected
PAEs
Bisphenol
A
(BPA)
tissues
E.encrasicolus
,
S.pilchardus
B.boops
M.barbatus
from
two
important
divisions
fisheries
(North
Aegean
Western
Ionian
Seas,
thereof
NAS
IOS
respectively)
Mediterranean
Sea.
The
level
contamination
varied
among
different
species
geographical
locations.
DEHP
(bis(2-ethylhexyl)
phthalate)
had
highest
mean
examined
all
four
examined.
Statistically
significant
differences
were
observed
between
(collected
NAS)
(from
IOS)
(p
<
0.05,
Wilcoxon
rank
test).
DIDP
(di-isodecyl
following
most
common
PAEs,
although
no
statistically
presented
sites,
species,
DINP
(di-isononyl
recorded
GIT
NAS),
while
rest
smaller
subset
samples.
Noticeably,
parent
diester
DBP
metabolic
monoester
MNBP
concurrently
detected
part
analyzed
risk
consumption,
based
on
Estimated
Daily
Intake
Target
Hazard
Quotient
(THQ),
showed
BPA
low
likelihood
negative
effect
occurring
every
scenario
examined,
THQ
indicated
there
higher
than
an
adverse
be
presented.
results
study
highlighted
need
future
efforts
focusing
factors
affecting
occurrences
environment,
especially
intended
Toxics,
Год журнала:
2023,
Номер
12(1), С. 28 - 28
Опубликована: Дек. 28, 2023
Perfluorooctanoic
acid
(PFOA)
in
environmental
matrices
is
increasingly
being
studied
due
to
its
persistence,
global
occurrence,
bioaccumulation,
and
associated
human
health
risks.
Some
indoor
environments
can
significantly
impact
the
of
occupants
pollutants
air
household
dust.
To
investigate
potential
exposure
individuals
PFOA
specific
confined
environments,
this
study
reports
an
analytical
method
results
concerning
determination
dust,
used
as
a
passive
sampler.
best
our
knowledge,
paper
represents
one
first
studies
concentrations
dust
collected
south
Italy,
within
European
region.
A
total
twenty-three
samples
were
from
two
different
areas
Sicily
(Palermo
Milena),
extracted,
analyzed
by
UHPLC-QTOF-MS/MS
system.
Finally,
was
estimated
using
new
index
(Indoor
Exposure
Index,
IPEX)
that
incorporates
levels
time,
correlation
between
blood.
It
then
compared
across
four
groups,
revealing
for
people
working
chemistry
laboratories
evaluated
be
ten
times
higher
than
homemakers.
Biosensors,
Год журнала:
2023,
Номер
13(12), С. 1005 - 1005
Опубликована: Ноя. 29, 2023
Dibutyl
phthalate
(DBP)
is
widely
used
as
a
plasticizer
in
the
production
of
polymeric
materials
to
give
them
flexibility,
strength
and
extensibility.
However,
due
its
negative
impact
on
human
health,
particular
reproductive
functions
fetal
development,
content
DBP
must
be
controlled
food
environment.
The
present
study
aims
develop
sensitive,
fast
simple
fluorescence
polarization
immunoassay
(FPIA)
using
monoclonal
antibodies
derived
against
(MAb-DBP)
for
detection
open
waters.
New
conjugates
with
various
fluorescein
derivatives
were
obtained
characterized:
5-aminomethylfluorescein
(AMF)
dichlorotriazinylaminofluorescein
(DTAF).
advantages
DBP-AMF
conjugate
FPIA
method
are
shown,
kinetics
binding
this
chemical
studied,
analysis
optimized,
concentration
selected
sensitivity
analysis—16
nM.
calibration
dependence
signal
was
obtained.
observed
IC50
(DBP
at
which
50%
decrease
occurs,
40
ng/mL)
limit
(LOD,
7.5
values
improved
by
factor
45
over
previously
described
polyclonal
antibodies.
This
technique
tested
recovery
method,
high
percentage
discovery
water
ranged
from
85
110%.
Using
developed
real
samples
Lake
Onega
tested,
good
correlation
shown
between
results
determination
GC-MS.
Thus,
work
can
determine
open-water
reservoirs.
Air Quality Atmosphere & Health,
Год журнала:
2024,
Номер
unknown
Опубликована: Апрель 3, 2024
Abstract
The
purposes
of
this
study
were
to
evaluate
the
bulk
sample
concentration
and
airborne
concentrations
phthalate
in
different
types
propellent
triggers
consumer
spray
products
estimate
health
risk
assessment
via
inhalation.
First,
analyzed
solutions
all
174
from
markets.
Then,
among
64
containing
phthalates,
10
propellant-type
selected
that
contained
high
concentrations;
measured
at
distances
1,
3,
5
m
nozzle
a
clean
room.
Four
phthalates
detected
products:
diisobutyl
(DiBP),
di-n-butyl
(DnBP),
butyl
benzyl
(BBzP),
bis(2-ethylhexyl)
(DEHP).
Among
products,
repellents
highest
mean
(3.90
ppm),
whereas
sterilized
lowest
(0.59
ppm).
trigger-type
cleaning
(4.54
coating
(0.73
In
both
propellant-
DnBP
DEHP
exceeded
standard
set
by
Ministry
Food
Drug
Safety
South
Korea.
No
significant
patterns
observed
for
DiBP,
DnBP,
(p
>
0.05).
Children
one
population
groups
most
susceptible
risks.
Overall,
product
air
products;
some
even
safe
limits.
Therefore,
should
be
used
well-ventilated
areas
avoid
respiratory
exposure.