Comprehensive analysis of antimicrobial resistance dynamics among broiler and duck intensive production systems
Scientific Reports,
Год журнала:
2025,
Номер
15(1)
Опубликована: Фев. 8, 2025
Abstract
Antimicrobial
resistance
(AMR)
is
a
global
health
challenge
requiring
cross-sector
action,
with
research
largely
focused
on
chickens,
leaving
ducks
underexplored.
This
study
examines
AMR
dynamics
in
Ross
308
broilers
and
Cherry
Valley
over
15
months
stocking
periods
under
consistent
rearing
conditions.
A
total
of
96
pooled
samples
were
collected:
50
from
broiler
farms
(26
biological,
24
environmental)
46
duck
(24
22
environmental).
Using
next-generation
shotgun
sequencing,
3,665
distinct
types
identified:
1,918
1,747
ducks.
Host-specific
AMRs
comprised
25.3%
18%
ducks,
while
56.7%
shared.
diversity
declined
across
production
phases,
losing
641
308,
yet
frequencies
increased
significantly
by
the
finisher
phase
(
p
<
0.0001).
Based
silico
data,
prophylactic
antibiotic
use
reduced
prevalence
multidrug-resistant
bacteria
both
poultry
species
0.05).
Hospital-acquired
infection-associated
higher
than
at
start
but
end
period
Above-average
markers
accounted
for
approximately
10%
all
detected
determinants.
Tetracycline
phenicol
resistances
emerged
as
most
prevalent.
13
high-resistance
carrier
(HRC)
shared
between
hosts.
Broiler-specific
HRCs
exhibited
abundances
(relative
frequency:
0.08)
duck-specific
0.003,
=
0.035).
The
grower
critical
intervention
point.
In
farm
environments
broiler-specific
9
biomarker
identified,
each
strongly
correlated
poultry-core
(correlation
coefficient
>
0.7).
Broiler
key
genes,
tetracycline
predominantly
associated
Bacteroides
coprosuis
,
Pasteurella
multocida
Acinetobacter
baumannii
.
Despite
its
limitations,
this
provides
insights
into
trends
two
major
types,
guiding
targeted
interventions
sustainable
management
strategies.
Язык: Английский
Combined effects of Macleaya cordata extract and antimicrobial peptides on reproductive performance and oviduct microbiota in Xuefeng black-bone chickens
Italian Journal of Animal Science,
Год журнала:
2025,
Номер
24(1), С. 508 - 520
Опубликована: Фев. 5, 2025
Язык: Английский
Evaluating the Biocontrol Potential of Bacillus subtilis Spores Against Listeria monocytogenes in Tryptic Soy Broth and Hummus
Applied Microbiology,
Год журнала:
2025,
Номер
5(2), С. 47 - 47
Опубликована: Май 15, 2025
This
study
evaluated
the
antimicrobial
potential
of
a
Bacillus
subtilis
spore-based
probiotic
cocktail
to
reduce
foodborne
pathogens
in
both
nutrient-rich
laboratory
media
and
complex
food
matrix
(hummus).
Three
common
pathogens—Listeria
monocytogenes,
Escherichia
coli
O157:H7,
Salmonella
Typhimurium—were
cultured
individually
full-strength,
half-strength,
quarter-strength
tryptic
soy
broth
(TSB)
with
or
without
spores
(~7
log
CFU/mL).
Additionally,
commercial
hummus
formulation
was
inoculated
L.
monocytogenes
(~3
CFU/g)
B.
stored
at
30
°C
simulate
temperature
abuse.
In
TSB,
E.
grew
~8.2
CFU/mL
full-strength
media,
no
significant
inhibition
by
probiotics.
However,
showed
substantial
suppression:
nutrient-limited
viable
counts
dropped
below
detection
limit
1.48
24
h
presence
hummus,
an
average
8.22
CFU/g
absence
probiotics
but
remained
significantly
lower
5.03
when
co-inoculated
(p
<
0.05).
Germination
confirmed
within
6
under
all
conditions.
These
findings
suggest
that
selectively
inhibit
Listeria,
particularly
nutrient
stress
abuse
While
had
limited
impact
on
Gram-negative
pathogens,
its
application
may
serve
as
clean-label
strategy
for
suppressing
ready-to-eat
(RTE)
foods.
dual-model
approach
provides
insights
into
mechanistic
activity
practical
limitations
spore
matrices.
Язык: Английский
Bacillus subtilis: A Promising Bacterial Candidate for One Health Applications
IntechOpen eBooks,
Год журнала:
2025,
Номер
unknown
Опубликована: Май 22, 2025
Bacillus
subtilis
is
widely
recognized
as
a
beneficial
and
safe
microbe
for
both
living
species
the
environment
due
to
its
broad
spectrum
of
bioactive
properties.
Used
decades
probiotic,
B.
produces
diverse
metabolites
with
antimicrobial,
antitumor,
antioxidant,
immunomodulatory
activities.
It
forms
resilient
biofilms,
sporulates
under
stress,
promotes
plant
growth,
enhances
nutrient
uptake,
controls
pathogens,
contributes
bioremediation
environmental
pollutants
such
heavy
metals
hydrocarbons.
Its
long-standing
use
in
food
fermentation
supports
safety
profile
recognition
organism
various
applications.
Consequently,
stands
out
promising
candidate
achieving
optimal
“One
Health”
outcomes
humans,
animals,
plants,
their
interconnected
ecosystems.
This
chapter
provides
biochemical
classification
derivatives
produced
by
subtilis,
highlighting
properties
functions
that
offer
health
benefits
organisms
environment.
Язык: Английский
Upgrading Isoquercitrin Concentration via Submerge Fermentation of Mulberry Fruit Extract with Edible Probiotics to Suppress Gene Targets for Controlling Kidney Cancer and Inflammation
The Journal of Microbiology,
Год журнала:
2024,
Номер
62(10), С. 919 - 927
Опубликована: Окт. 1, 2024
Язык: Английский
Effects of dietary Bacillus subtilis 14823 on growth performance, gut barrier integrity and inflammatory response of broilers raised in a stressful tropical environment
Poultry Science,
Год журнала:
2024,
Номер
104(1), С. 104518 - 104518
Опубликована: Ноя. 6, 2024
Heat
stress
(HS)
has
become
a
major
concern
for
the
poultry
industry
in
many
countries.
HS
impacts
gut
health
by
causing
damaged
mucosal
microstructures,
increased
oxidative
stress,
weakened
immunity,
and
heightened
permeability
to
toxins
pathogens.
We
investigated
potential
benefits
broiler
chickens
subjected
of
dietary
supplementation
with
Bacillus
subtilis
14823.
Growth
performance,
barrier
integrity,
expressions
inflammatory
cytokines
were
analyzed.
The
results
indicated
that
B.
spores
at
concentrations
1
×
10
Язык: Английский
Probiotic Applications of Bacillus subtilis
IntechOpen eBooks,
Год журнала:
2024,
Номер
unknown
Опубликована: Окт. 31, 2024
Probiotics
are
defined
as
live
microorganisms
that
confer
health
advantages
to
their
hosts.
Some
probiotics
exhibit
limitations,
including
susceptibility
temperature
fluctuations,
gastric
acidity,
and
harsh
conditions.
This
has
led
exploring
with
higher
intrinsic
resistance
stability
in
Bacillus
subtilis
received
attention
due
its
inherent
probiotic
properties,
high
conditions,
ability
form
spores.
Significant
progress
been
made
understanding
the
potential
of
B.
subtilis,
uncovering
various
mechanisms
action.
On
other
hand,
postbiotics
secreted
by
have
become
an
attractive
field
interest
for
scientists.
Numerous
studies
validated
efficacy
a
dietary
supplement
poultry
aquaculture.
Furthermore,
Food
Drug
Administration
(FDA)
recognized
safe.
These
advantageous
properties
position
highly
promising
applications.
Язык: Английский
B. subtilis Probiotics for Humans, Animals and Plants: Mechanisms, Applications and Prospects
IntechOpen eBooks,
Год журнала:
2024,
Номер
unknown
Опубликована: Дек. 3, 2024
Bacillus
bacteria
have
increasingly
attracted
research
interest
due
to
their
promising
probiotic
properties,
including
strong
antimicrobial,
antidiarrheal,
and
immunostimulatory
effects.
They
are
able
stimulate
the
growth
of
natural
flora,
prevent
intestinal
inflammation,
demonstrate
excellent
stability
even
under
adverse
conditions.
This
chapter
explores
applications
subtilis
strains
in
humans,
animals,
plants.
First,
reviews
mechanisms
B.
current
state
this
area.
The
potential
recombinant
probiotics
also
covered,
along
with
results
from
preclinical
studies
future
role
therapy
clinical
settings.
aims
survey
landscape
hypothesize
about
its
impact.
Язык: Английский