Lipid-based nanodelivery systems of curcumin: Recent advances, approaches, and applications
Food Chemistry,
Год журнала:
2024,
Номер
463, С. 141193 - 141193
Опубликована: Сен. 11, 2024
Язык: Английский
Curcumin nanopreparations: recent advance in preparation and application
Biomedical Materials,
Год журнала:
2024,
Номер
19(5), С. 052009 - 052009
Опубликована: Авг. 27, 2024
Abstract
Curcumin
is
a
natural
polyphenolic
compound
extracted
from
turmeric
with
antibacterial,
antioxidant,
antitumor,
preventive
and
therapeutic
neurological
disorders
variety
of
bioactivities,
which
widely
used
in
the
field
food
medicine.
However,
drawbacks
curcumin
such
as
poor
aqueous
solubility
stability
have
limited
practical
application
curcumin.
To
overcome
these
defects
enhance
its
functional
properties,
various
nanoscale
systems
(liposomes,
polymer
nanoparticles,
protein
solid
lipid
metal
etc)
been
extensively
employed
for
encapsulation
delivery.
Despite
rapid
development
nanoformulations,
there
lack
comprehensive
reviews
on
their
preparation
properties.
This
review
provides
an
overview
construction
nano-delivery
systems,
mechanisms
action,
nanocarrier
methods
applications
nanocarriers
pharmaceutical
fields
to
provide
theoretical
basis
technological
support
efficient
bio-utilization,
product
early
clinical
Язык: Английский
Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) for the delivery of bioactives sourced from plants: part I – composition and production methods
Expert Opinion on Drug Delivery,
Год журнала:
2024,
Номер
21(10), С. 1479 - 1490
Опубликована: Окт. 2, 2024
Nanoparticles
(NPs)
are
widely
used
in
the
pharmaceutical
field
to
treat
various
human
disorders.
Among
these,
lipid-based
NPs
(LNPs),
including
solid
lipid
nanoparticles
(SLN)
and
nanostructured
carriers
(NLC),
favored
for
drug/bioactive
delivery
due
their
high
stability,
biocompatibility,
encapsulation
efficiency,
sustained/controlled
release.
These
properties
make
them
particularly
suitable
as
of
compounds
derived
from
plant
sources.
Язык: Английский
Nanocarriers for nutraceutical delivery: A miniaturized revolution in health
Rajashri B. Sawant,
Sonali P. Nikam,
Arpita Roy
и другие.
Nano-Structures & Nano-Objects,
Год журнала:
2024,
Номер
39, С. 101321 - 101321
Опубликована: Сен. 1, 2024
Язык: Английский
Enhanced protection and bioavailability of Lycium barbarum leaf extract through encapsulation in whey protein isolate and bovine serum albumin nanoparticles
Food Chemistry,
Год журнала:
2024,
Номер
463, С. 141506 - 141506
Опубликована: Окт. 1, 2024
Язык: Английский
Recent advances in the development and application of curcumin-loaded micro/nanocarriers in food research
Advances in Colloid and Interface Science,
Год журнала:
2024,
Номер
335, С. 103333 - 103333
Опубликована: Ноя. 4, 2024
Язык: Английский
Green Preparation, Characterization, Wound Healing Assessment, and Histopathological Evaluation of Vitamin A Encapsulated in Niosome and Solid Lipid Nanoparticle
Pharmaceutical Sciences,
Год журнала:
2023,
Номер
30(1), С. 70 - 84
Опубликована: Дек. 9, 2023
Background:
The
purpose
of
the
current
work
was
to
manufacture
vitamin
A
(Vit
A)
niosome
and
solid
lipid
nanoparticle
(SLN)
using
an
ultrasonic
approach
evaluate
its
effect
on
wound
healing.
Methods:
nanoparticles
were
prepared
through
ultrasonication
technique
characterized
by
dynamic
light
scattering
(DLS),
transmission
electron
microscopy
(TEM).
Further,
evaluated
for
their
various
parameters
such
as
pH,
viscosity,
spreadability,
stability,
in-vitro
drug
release
study,
cytotoxicity,
in-vivo
Results:
TEM
confirmed
spherical
nature
Vit
A-niosome
SLN.
formulations
(niosome
SLN)
stable
in
accelerated
stability
test
(freeze-thaw
cycle).
from
SLN
gel
significantly
higher
(almost
70
80%,
respectively)
than
simple
gel.
According
animal
healing
closure
niosomal
greater
other
groups
during
21
days
after
surgery
(P
<
0.05)
close
each
over
time
day
21.
Based
histological
data,
wounds
treated
with
A-SLN
had
more
collagen
groups.
MDA
malondialdehyde
(MDA,
end-product
peroxidation)
decreased
group
days,
while
glutathione
peroxidase
(GPx),
superoxide
dismutase
(SOD,
endogenous
antioxidant),
hydroxyproline
levels
demonstrated
increase.
Conclusion:
findings
this
study
revealed
that
nano-formulations
could
be
used
a
possible
safe
nano-vesicle
cutaneous
delivery
thus
potentially
opening
up
new
prospects
treatment
disorders.
Язык: Английский
Improving antifungal effect of peppermint essential oil
Acta Scientiarum Polonorum Hortorum Cultus,
Год журнала:
2024,
Номер
23(2), С. 29 - 42
Опубликована: Апрель 30, 2024
Nanoencapsulation
of
essential
oils
is
a
promising
strategy
for
extending
their
antifungal
activity
and
addressing
evaporation
decomposition
in
unfavorable
environmental
conditions.
This
research
aimed
to
synthesize
compare
the
physical
properties
solid
lipid
nanoparticles
(SLNs)
containing
peppermint
oil
(PE)
during
12
months
storage
at
various
temperatures
(4°C,
25°C,
27°C
with
60%
relative
humidity,
37°C,
40°C
75%
humidity),
investigate
compared
free
PE.
The
SLN
formulations
were
prepared
using
high-shear
homogenization
ultrasound
techniques
analyzed
particle
size
analyzer,
differential
scanning
calorimetry,
transmission
electron
microscopy,
microscopic
images
fungal
mycelium
assess
encapsulation
efficacy.
results
showed
that
PE-SLNs
had
164.2
±5.8
nm,
PDI
value
0.176
±0.01,
zeta
potential
–11.3
mV,
an
percentage
approximately
75
±0.5%.
Overall,
slight
acceptable
increase
over
12-month
period
all
investigated
temperatures.
Furthermore,
vitro
inhibition
PE
concentration
2000
μL
L–1
against
Penicillium
italicum
P.
digitatum
was
66.7%
±2.6
66.8%
±0.8,
respectively,
while
it
88.8%
±0.9
89.9%
±1.4.
These
demonstrate
SLNs
as
effective
carrier
sustained
delivery
improved
storage.
Язык: Английский
Physicochemical and biological characterization of the lipid particles with bovine serum albumin corona
International Journal of Biological Macromolecules,
Год журнала:
2024,
Номер
281, С. 136223 - 136223
Опубликована: Окт. 2, 2024
Язык: Английский
Challenges and Strategies for Bioavailability of Curcumin
Опубликована: Янв. 1, 2023
Phytochemicals
have
been
highlighted
in
several
sectors
of
industry
due
to
their
different
biological
activities.
In
fact,
the
curcumin
is
a
polyphenol
extracted
from
rhizome
turmeric
(Curcuma
longa)
consumed
form
kitchen
spices
since
ancient
times
which
it
has
demonstrated
beneficial
health
effects
such
as
antioxidant,
anti-inflammatory,
anti-carcinogenic,
anti-tumor,
and
so
on.
However,
concentration
bloodstream
very
low
its
high
hydrophobicity,
absorption
intestinal
physiological
conditions,
metabolism
rate
liver,
rapid
excretion
by
gallbladder.
Poor
bioavailability
limited
bioactivity
phytochemical.
Efforts
made
improve
upon
this
using
chemical
modification
encapsulation
approaches.
Considering
versatility,
safety,
biocompatibility,
technologies
more
effective
improved
dispersibility,
stability,
bioavailability,
phytochemicals
vivo
vitro
assays.
Therefore,
chapter
focused
on
aspects
involved
(e.g.,
solubility,
food
matrix
effects)
phytochemical
with
great
potential
for
cancer
neurodegenerative
diseases
chemopreventive
effect.
We
also
strategies
used
enhance
based
resulting
nanoparticle
drug
delivery
systems.
The
topic
discussed
here
should
contribute
research
related
approaches
other
improving
and,
consequently,
human
conditions.
Язык: Английский