International Journal of Molecular Sciences, Год журнала: 2024, Номер 25(10), С. 5548 - 5548
Опубликована: Май 19, 2024
With the increasing rate of antimicrobial resistance phenomenon, natural products gain our attention as potential drug candidates. Apart from being used nutraceuticals and for biotechnological purposes, microalgae phytoplankton have well-recognized compounds proved anti-infectious potential. In this review, we comprehensively outline activity one genus cyanobacteria (Arthrospira, formerly Spirulina) eukaryotic (Dunaliella). Both, especially Arthrospira, are mostly a source antioxidants health supplements, cancer therapy cosmetics. Their diverse bioactive provide other bioactivities various medical applications. antibacterial antifungal vary in broad range strain specific. There strains Arthrospira platensis with very potent minimum inhibitory concentrations (MICs) low 2–15 µg/mL against bacterial fish pathogens including Bacillus Vibrio spp. sp. has demonstrated an inhibition zone (IZ) 50 mm Staphylococcus aureus. Remarkable is substantial amount vivo studies showing it to be promising preventing vibriosis shrimp Helicobacter pylori infection wound healing. The innovative laser irradiation chlorophyll releases can cause photodynamic destruction bacteria. Dunaliella salina exhibited MIC values lower than 300 IZ value 25.4 on different bacteria, while tertiolecta 25 μg/mL some These fulfill criteria significant sometimes comparable or exceed control antibiotics. which responsible that action fatty acids PUFAs, polysaccharides, glycosides, peptides, neophytadiene, etc. Cyanobacteria, such also particularly flavonoids, terpenes, alkaloids, saponins, quinones unique-to-them compounds, phycobiliproteins, polyhydroxybutyrate, peptide microcystin, metabolites optimized by using stress factors two-step process fermentation closed photobioreactors (PBRs).
Язык: Английский
Процитировано
12Chemical Composition, Bioactivities, and Applications of Spirulina (Limnospira platensis) in Food, Feed, and Medicine
Foods, Год журнала: 2024, Номер 13(22), С. 3656 - 3656
Опубликована: Ноя. 17, 2024
Spirulina (
Язык: Английский
Процитировано
8Emerging trends in algae farming on non-arable lands for resource reclamation, recycling, and mitigation of climate change-driven food security challenges
Reviews in Environmental Science and Bio/Technology, Год журнала: 2024, Номер 23(3), С. 869 - 896
Опубликована: Авг. 7, 2024
Язык: Английский
Процитировано
5Unraveling the lipidome of Pavlova gyrans, a natural reservoir of bioactive lipids for biotechnological applications
Journal of Applied Phycology, Год журнала: 2025, Номер unknown
Опубликована: Янв. 2, 2025
Язык: Английский
Процитировано
0Antimicrobial and Ecological Potential of Chlorellaceae and Scenedesmaceae with a Focus on Wastewater Treatment and Industry
Fermentation, Год журнала: 2024, Номер 10(7), С. 341 - 341
Опубликована: Июнь 28, 2024
A complex evaluation of antimicrobial activities microalgae, including those relevant to wastewater treatment (WWT), in light the integrated biorefinery concept, is performed. An example this concept linking a commercial microalgal system plants, factories, or farms that emit polluted (WW). The microalgae would not only metabolize pollutants—such as nitrogen (N) and phosphorus (P)—from WW, thus fueling their biomass, but they exert an antibacterial effect against pathogenic bacteria there. biomass then could be harvested used for biofertilizers, biofuels, bioplastics might possibly utilized animal feed, other pharmaceutical agents. large amount research on activity WWT potential focuses families Chlorellaceae Scenedesmaceae, which are also some most commercially strains microalgae. For reason, species chosen current review. Furthermore, increasing resistance necessitates search antibiotic alternatives, antifungal Scenedesmaceae very promising. Microalgae rich compounds like polyunsaturated fatty acids (PUFAs), polysaccharides, carotenoids, proteins, etc., extracts possess effects. vitro has varied broad range from low strong no effect. Several have fulfilled criteria outstanding high activity, especially C. vulgaris spp., with equal better than control antibiotics. There were several minimum inhibitory concentrations (MIC) below 80 µg/mL even 10 1.5 µg/mL; had inhibition zones (IZ) over 30 mm, 48 mm. In vivo results promising scarce, all warrants further situ studies—from models clinical environmental trials. Altogether, important data circle economy, urgent necessity decrease CO2 emissions fight climate change, curb harmful influence future pandemics presented. This review paves way utilizing total system.
Язык: Английский
Процитировано
4Microalgae-Derived Peptides: Exploring Bioactivities and Functional Food Innovations
Journal of Agricultural and Food Chemistry, Год журнала: 2025, Номер unknown
Опубликована: Янв. 6, 2025
A variety of bioactive peptides with unique and diverse structures could be found in microalgae various bioactivities including antioxidant, antihypertensive, antibacterial bioactivities. Food products containing hold significant health nutrition potential. Peptide liberation through enzymatic other processes enhanced protein extraction, some animal studies were conducted to verify their health-promoting effects. Various have focused on developing practical methods for production, purification, identification peptides. The emerging trends silico peptide therapies, computational approaches, artificial intelligence, the prospects research are briefly highlighted. Moreover, this article potential microalgae-derived as functional food ingredients role promoting health, future applications nutraceutical industries. It also discussed challenges bioavailability foods.
Язык: Английский
Процитировано
0Dairy Wastewaters to Promote Mixotrophic Metabolism in Limnospira (Spirulina) platensis: Effect on Biomass Composition, Phycocyanin Content, and Fatty Acid Methyl Ester Profile
Life, Год журнала: 2025, Номер 15(2), С. 184 - 184
Опубликована: Янв. 26, 2025
This study explores the mixotrophic cultivation of Limnospira platensis using dairy byproducts, specifically scotta whey (SW), buttermilk wastewater (BMW), and (DWW), to promote biomass production enhance composition bioactive compounds. By assessing various concentrations (1%, 2%, 4% v v−1) these byproducts in a modified growth medium, this aims evaluate their effect on L. growth, phycocyanin (C-PC) content, fatty acid methyl ester (FAME) profiles. The results show that optimal was achieved with 2% wastewater, reaching maximum 3.30 g L−1 3.19 L−1, respectively. Mixotrophic led increased C-PC yields, especially treatments, highlighting potential for producing valuable pigments. Additionally, FAME profiles indicated minimal changes compared control, oleic γ-linolenic acids being dominant conditions. These findings support viability utilizing sustainable cultivation, contributing circular bioeconomy while compounds nutritional commercial interest.
Язык: Английский
Процитировано
0Marine Phytoplankton Bioactive Lipids and Their Perspectives in Clinical Inflammation
Marine Drugs, Год журнала: 2025, Номер 23(2), С. 86 - 86
Опубликована: Фев. 17, 2025
Marine phytoplankton is an emerging source of immunomodulatory bioactive lipids (BLs). Under physiological growth conditions and upon stress challenges, several eukaryotic microalgal species accumulate lipid metabolites that resemble the precursors animal mediators inflammation: eicosanoids prostaglandins. Therefore, marine could serve as a biotechnological platform to produce functional BLs with therapeutic applications in management chronic inflammatory diseases other clinical conditions. However, be commercially competitive, lipidic precursor yields should enhanced. Beside tailoring cultivation native producers, genetic engineering feasible strategy accrue production introduce heterologous biosynthetic pathways hosts. Here, we present state-of-the-art research on from discuss synthetic biology approaches boost their light-driven biosynthesis.
Язык: Английский
Процитировано
0The Invisible Threat of Antibiotic Resistance in Food
Antibiotics, Год журнала: 2025, Номер 14(3), С. 250 - 250
Опубликована: Март 1, 2025
The continued and improper use of antibiotics has resulted in the emergence antibiotic resistance (AR). dissemination antibiotic-resistant microorganisms occurs via a multitude pathways, including food supply. failure to comply with regulatory withdrawal period associated treatment domestic animals or illicit as growth promoters contributed proliferation bacteria meat dairy products. It was demonstrated that not only do animal human pathogens act donors genes, but also lactic acid can serve reservoirs genes encoding for resistance. Consequently, consumption fermented foods presents potential conduit AR. This review provides an overview transmission range traditional novel foods. literature data reveal foodborne microbes be significant factor
Язык: Английский
Процитировано
0Optimizing Microalgae Bioprocessing and Digestibility: spraying techniques for drying and encapsulation
Food Bioscience, Год журнала: 2025, Номер unknown, С. 106288 - 106288
Опубликована: Март 1, 2025
Язык: Английский
Процитировано
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