International Journal of Molecular Sciences, Год журнала: 2024, Номер 25(24), С. 13302 - 13302

Опубликована: Дек. 11, 2024

This review aims to address the significant challenges of treating central nervous system (CNS) disorders such as neurodegenerative diseases, strokes, spinal cord injuries, and brain tumors. These are difficult manage due complexity disease mechanisms protective blood–brain barrier (BBB), which restricts drug delivery. Recent advancements in nanoparticle (NP) technologies offer promising solutions, with potential applications delivery, neuroprotection, neuroregeneration. By examining current research, we explore how NPs can cross BBB, deliver medications directly targeted CNS regions, enhance both diagnostics treatment. Key NP strategies, passive targeting, receptor-mediated transport, stimuli-responsive systems, demonstrate encouraging results. Studies show that may improve minimize side effects, increase therapeutic effectiveness models Alzheimer’s, Parkinson’s, stroke, glioblastoma. thus represent a approach for disorder management, combining delivery diagnostic capabilities enable more precise effective treatments could significantly benefit patient outcomes.

Язык: Английский