Use of Nicotinamide Mononucleotide as Non-Natural Cofactor

Catalysts, Год журнала: 2025, Номер 15(1), С. 37 - 37

Опубликована: Янв. 3, 2025

Nicotinamide mononucleotide (NMN) has emerged as a promising non-natural cofactor with significant potential to transform biocatalysis, synthetic biology, and therapeutic applications. By modulating NAD⁺ metabolism, NMN offers unique advantages in enzymatic reactions, metabolic engineering, regenerative medicine. This review provides comprehensive analysis of NMN’s biochemical properties, mechanisms action, diverse Emphasis is placed on its role addressing challenges multi-enzyme cascades, biofuel production, the synthesis high-value chemicals. The paper also highlights critical research gaps, including need for scalable methods, improved integration into systems, toxicity studies use. Emerging technologies such AI-driven enzyme design CRISPR-based genome engineering are discussed transformative tools optimizing NMN-dependent pathways. Furthermore, synergistic biology innovations, cell-free systems dynamic regulatory networks, explored, paving way precise modular biotechnological solutions. Looking forward, versatility positions it pivotal tool advancing sustainable bioprocessing precision Addressing current limitations through interdisciplinary approaches will enable redefine boundaries innovation. serves roadmap leveraging across scientific industrial domains.

Язык: Английский

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Emerging applications of biorecognition elements-based optical biosensors for food safety monitoring

Опубликована: Фев. 14, 2025

Язык: Английский

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Porous Polysulfone/Activated Carbon Capsules as Scaffolds for Enzyme Immobilization

C – Journal of Carbon Research, Год журнала: 2025, Номер 11(1), С. 14 - 14

Опубликована: Фев. 17, 2025

Enzymes play a vital role in various industrial sectors and are essential components of many products. Hybrid enzyme-polymeric capsules were developed using polysulfone-activated carbon as scaffolds. The with an average diameter 2.55 mm fabricated by applying phase inversion precipitation method. An increase the amount immobilized enzymes was observed growth activated polysulfone matrix. Enzyme immobilization confirmed Bradford method, while Viscozyme® L activity carboxymethyl cellulose hydrolysis to glucose measured Reducing Sugar DNS recycling hybrid L-polysulfone/activated capsules, their reuse for subsequent investigated demonstrated repeatability results.

Язык: Английский

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Advancements and challenges in microalgal protein production: A sustainable alternative to conventional protein sources

Microbial Cell Factories, Год журнала: 2025, Номер 24(1)

Опубликована: Март 10, 2025

Abstract The increasing global demand for sustainable protein sources necessitates the exploration of alternative solutions beyond traditional livestock and crop-based proteins. Microalgae present a promising due to their high content, rapid biomass accumulation, minimal land water requirements. Furthermore, ability thrive on non-arable in wastewater systems enhances sustainability resource efficiency. Despite these advantages, scalability economical feasibility remain major challenges microalgal production. This review explores recent advancements cultivation extraction technologies, including pulsed electric field, ultrasound-assisted extraction, enzyme-assisted microwave-assisted extraction. These innovative techniques have significantly improved efficiency, purity, sustainability, while addressing cell wall disruption recovery challenges. Additionally, examines digestibility bioavailability, particularly context human nutrition aquafeed applications. A critical analysis life cycle assessment studies highlights environmental footprint production compared conventional sources. Although requires significant energy inputs, biorefinery approaches, carbon dioxide sequestration, industrial integration can help mitigate limitations. Finally, this outlines key future research directions, emphasizing need cost reduction strategies, genetic engineering enhanced yields, industrial-scale process optimization. By integrating with models, proteins hold immense potential as sustainable, high-quality source food, feed, nutraceutical

Язык: Английский

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Microbial tannases: biosynthesis, purification, characterization and potential industrial applications

International Journal of Biological Macromolecules, Год журнала: 2025, Номер unknown, С. 143376 - 143376

Опубликована: Апрель 1, 2025

Язык: Английский

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