Molecular Nutrition & Food Research, Год журнала: 2025, Номер unknown
Опубликована: Май 20, 2025
ABSTRACT Dietary fiber, especially resistant starch (RS) Type 2 (RS2) found in high‐amylose maize (HAMS), is vital for gut health and helps prevent colon cancer. In contrast to most nutrients, dietary fiber not degraded by the intestinal enzymes; it reaches distal parts of gut, where fermented microbiota into short‐chain fatty acids (SCFAs), such as acetate, propionate, butyrate. SCFAs energize colonocytes, reduce inflammation, enhance immunity. HAMS absorbed colon, ferments create that feed good flora have antiinflammatory antiproliferative effects. RS2 modulates gene signaling, activates tumor‐suppressor genes like tumor suppressor protein (p53), exhibits antidiabetic, cholesterol‐lowering, Incorporation RS2‐rich sources enhances barriers, decreases colorectal cancer biomarkers, counteracts negative impacts low‐fiber Western diets, making a promising functional food chronic disease prevention promotion.
Язык: Английский