
Antibiotics, Год журнала: 2024, Номер 13(12), С. 1228 - 1228
Опубликована: Дек. 18, 2024
Biofilms are structured microbial communities that adhere to various abiotic and biotic surfaces, where organisms encased in an exo-polysaccharide matrix. Organisms within biofilms use mechanisms help them resist external challenges, such as antibiotics, rendering more resistant drugs. Therefore, researchers have attempted develop suitable laboratory models study the physical features of biofilms, their resistance against antimicrobial agents, gene protein expression profiles. However, current suffer from limitations. In this comprehensive review, we summarized designs been used for biofilm models, presenting strengths Additionally, provided insight into improving these closely simulate real-life scenarios, using newly developed techniques additive manufacturing, synthetic biology, bioengineering.
Язык: Английский