ACS symposium series,
Год журнала:
2024,
Номер
unknown, С. 259 - 276
Опубликована: Ноя. 1, 2024
Tissue
loss
burdens
the
medical
and
health-care
departments
considerably.
engineering
(TE)
is
a
derivative
of
biomedical
because
it
creates
appropriate
functional
alternatives
for
regenerating
damaged
tissues
organs.
The
success
TE
hinges
significantly
on
development
engineered
biocompatible
materials.
These
materials
must
have
superior
anatomical
structure,
functionality,
mechanical
properties,
histocompatibility
to
support
tissue
regeneration
repair
processes
effectively.
Since
mid-19th
century,
researchers
focused
biopolymer-based
systems
applications,
especially
as
healing
devices
temporary
implants
scaffolds
repair.
Biopolymers
emerged
prime
candidates
their
renewable
natural
resources.
By
utilizing
supercritical
fluids
obtained
from
bio-based
polymers,
there
heightened
focus
mitigating
harmful
effects
synthetic
polymer
in
wound
other
applications.
This
chapter
summarizes
history
progress
various
biopolymers
Gels,
Год журнала:
2024,
Номер
10(9), С. 547 - 547
Опубликована: Авг. 23, 2024
Regenerative
hydrogels
from
natural
polymers
have
come
forth
as
auspicious
materials
for
use
in
regenerative
medicine,
with
interest
attributed
to
their
intrinsic
biodegradability,
biocompatibility,
and
ability
reassemble
the
extracellular
matrix.
This
review
covers
latest
advances
used
wound
healing,
focusing
on
chemical
composition,
cross-linking
mechanisms,
functional
properties.
Key
carbohydrate
polymers,
including
alginate,
chitosan,
hyaluronic
acid,
polysaccharide
gums,
agarose,
carrageenan,
xanthan
gum,
are
discussed
terms
of
sources,
structures
specific
properties
suitable
applications.
The
further
explores
categorization
based
ionic
charge,
response
physiological
stimuli
(i.e.,
pH,
temperature)
particularized
roles
tissue
self-healing.
Various
methods
enhance
mechanical
biological
performance
these
also
examined.
By
highlighting
recent
innovations
ongoing
challenges,
this
article
intends
give
a
detailed
understanding
potential
revolutionize
medicine
improve
patient
healing
outcomes.
Soft Matter,
Год журнала:
2024,
Номер
20(19), С. 4021 - 4034
Опубликована: Янв. 1, 2024
A
new
3D
bioprinted
biomaterial,
with
flax
fiber-reinforced
alginate
hydrogel,
is
developed.
The
study
assesses
the
impact
of
fibers
on
printing,
mechanical,
4D
and
geometric
properties
composite.
Three-dimensional
(3D)-printing,
also
known
as
additive
manufacturing,
has
revolutionized
various
industries,
including
biomedical
devices,
by
enabling
the
production
of
personalized
implants
tailored
to
individual
patient
anatomical
variations.
This
review
article
provides
an
overview
applications
3D-Printed
Medical
Implants.
By
leveraging
advanced
imaging
modalities
and
digital
modeling
software,
clinicians
can
design
fabricate
that
ensure
optimal
fit,
function,
biocompatibility
for
each
patient.
Additionally,
3D-printing
transformed
cancer
treatment
well
neurodegenerative
disorders
facilitating
fabrication
patient-specific
medical
devices
used
in
surgical
oncology,
radiation
therapy,
reconstructive
surgery.
These
customized
enhance
efficacy
while
minimizing
adverse
effects
precisely
targeting
cancerous
tissues.
Moreover,
technology
enables
development
3D
cell
cultures,
bridging
gap
between
traditional
2D
cultures
vivo
models.
advancement
enhances
researchers'
capabilities
studying
progression
evaluating
responses
therapeutic
interventions.
Furthermore,
bioprinting
shows
promise
a
approach
neurological
diseases,
with
preclinical
studies
demonstrating
3D-printed
neural
tissue
scaffolds
implantable
drug
delivery
platforms.
Overall,
holds
significant
potential
medicine,
offering
innovative
solutions
improve
outcomes
across
disciplines.
Biomaterials Science,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 1, 2025
The
development
of
bioink-based
3D-printed
scaffolds
has
revolutionized
bone
tissue
engineering
(BTE)
by
enabling
patient-specific
and
biomimetic
constructs
for
regeneration.
Frontiers in Cell and Developmental Biology,
Год журнала:
2024,
Номер
12
Опубликована: Май 21, 2024
Various
in
vitro
three-dimensional
(3D)
tissue
culture
models
of
human
and
diseased
skin
exist.
Nevertheless,
there
is
still
room
for
the
development
improvement
3D
bioprinted
cancer
models.
The
need
reproducible
bioprinting
methods,
cell
samples,
biomaterial
inks,
bioinks
becoming
increasingly
important.
influence
viscosity
hydrogels
on
spreading
migration
most
types
cells
well
studied.
There
are
however
limited
studies
In
this
review,
we
will
outline
importance
studying
various
cancers
by
using
We
provide
an
overview
advantages
disadvantages
technologies.
emphasize
how
relates
to
cells.
Lastly,
give
specific
Materials Today Bio,
Год журнала:
2024,
Номер
29, С. 101341 - 101341
Опубликована: Ноя. 14, 2024
Bioprinting
and
bioinks
are
two
of
the
game
changers
in
bone
tissue
engineering.
This
review
presents
different
bioprinting
technologies
including
extrusion-based,
inkjet-based,
laser-assisted,
light-based,
hybrid
with
their
own
strengths
weaknesses.
will
aid
researchers
selection
assessment
bioink;
discussion
ranges
from
commercially
available
to
custom
lab-made
formulations
mainly
based
on
natural
polymers,
such
as
agarose,
alginate,
gelatin,
collagen,
chitosan,
designed
for
The
is
centered
technological
advancements
increasing
clinical
demand
within
rapidly
growing
market.
From
this
point
view,
4D,
5D,
6D
printing
promise
a
future
where
unprecedented
levels
innovation
be
involved
fabrication
processes
leading
more
dynamic
multifunctionalities
bioprinted
constructs.
Further
advances
technology,
methods
covered,
meet
personalized
medicine
goals
while
advancing
patient
outcomes
tissues
engineering
applications.
Gels,
Год журнала:
2024,
Номер
10(5), С. 323 - 323
Опубликована: Май 9, 2024
Hydrogels,
which
are
three-dimensional
networks
of
hydrophilic
polymers
capable
absorbing
and
retaining
large
amounts
water,
have
emerged
as
versatile
materials
with
vast
potential
in
various
fields
[...]
Biomedical Materials,
Год журнала:
2024,
Номер
19(6), С. 065026 - 065026
Опубликована: Окт. 2, 2024
This
paper
describes
the
extrusion
pressure's
effect
on
composite
hydrogel
inks'
filaments
subjected
to
three
point
bending
collapse
tests.
The
considered
in
this
work
consists
of
an
alginate-poloxamer
reinforced
with
flax
fibres.
Increased
pressure
resulted
more
asymmetrical
between
support
pillars.
Furthermore,
material
and
printing
conditions
used
present
study
led
production
curved
specimens.
These
two
characteristics
implicitly
limit
validity
yield
stress
equations
commonly
open
literature.
Therefore,
a
new
system
was
derived
for
case
filaments.
A
post-processing
method
also
created
obtain
properties
required
evaluate
stress.
equation
then
implemented
identify
strength
failed
hydrogels
without
fibre
reinforcement.
statistical
analysis
showed
equation's
significance,
which
yielded
statistically
higher
(i.e.
1.15
times
larger)
values
compared
numbers
obtained
literature
equations.
At
larger
pressures,
longer
periods
were
needed
converge
towards
its
final
shape.
Larger
lower
stresses
within
filament:
5
kPa
increase
lowered
by
19%.
In
comparison,
15
29%
decrease
Overall
provides
guidelines
standardize
tests
comparison
different
materials.
