Genes, Год журнала: 2022, Номер 13(3), С. 454 - 454
Опубликована: Март 2, 2022
The current diversity of metazoans has been achieved through a long process evolution since the appearance their unicellular ancestor about 1000 Mya [...].
Язык: Английский
GigaScience, Год журнала: 2021, Номер 10(5)
Опубликована: Май 1, 2021
Abstract Background Venoms are deadly weapons to subdue prey or deter predators that have evolved independently in many animal lineages. The genomes of venomous animals essential understand the evolutionary mechanisms involved origin and diversification venoms. Results Here, we report chromosome-level genome Mediterranean cone snail, Lautoconus ventricosus (Caenogastropoda: Conidae). total size assembly is 3.59 Gb; it has high contiguity (N50 = 93.53 Mb) 86.6 Mb assembled into 35 largest scaffolds pseudochromosomes. On basis venom gland transcriptomes, annotated 262 complete genes encoding conotoxin precursors, hormones, other venom-related proteins. These were scattered different pseudochromosomes located within repetitive regions. precursors normally structured 3 exons, which did not necessarily coincide with structural domains corresponding Additionally, found evidence L. for a past whole-genome duplication event by means conserved gene synteny Pomacea canaliculata genome, only one available at chromosome level Caenogastropoda. was further confirmed presence duplicated hox cluster. Key gastropod biology including those proteins related development, shell formation, sex genome. Conclusions new high-quality should become reference assembling analyzing will contribute future genomic studies among animals.
Язык: Английский
Процитировано
44
Frontiers in Immunology, Год журнала: 2022, Номер 13
Опубликована: Ноя. 10, 2022
In invertebrates, the innate immune system protects against a wide range of microbiological infections. Several immunological processes are involved in interactive response between snails and their parasites, including phagocytosis, nitric oxide synthesis, phenol oxidase activity, lysozymes, lectin formation. The responses connected to interaction parasites discussed detail current research. Understanding nature these reactions will enable scientists explore approaches eliminate cure parasitic
Язык: Английский
Процитировано
13
Fish & Shellfish Immunology, Год журнала: 2023, Номер 137, С. 108791 - 108791
Опубликована: Май 3, 2023
The internal defense system of mollusks represents an efficient protection against pathogens and parasites, involving several biological immune processes, such as phagocytosis, encapsulation, cytotoxicity, antigenic recognition self/non-self. Mollusks possess professional, migratory, circulating cells that play a key role in the organism, hemocytes. Several studies have been performed on hemocytes from different mollusks, but, to date, these are still scarcely explored. Different hemocyte populations found, according presence or absence granules, size, species studied. Our study aims deepen knowledge gastropod Aplysia depilans using morphological techniques light confocal microscopy, testing Toll-like receptor 2, inducible nitric oxide synthetase, nicotinic acetylcholine alpha 7 subunit. results show two distinguishable by presence/absence granules cytoplasm, strongly positive for antibodies tested, suggesting first time receptors surface sea hare immunohistochemistry. These data help understanding this gastropod, providing additional comprehending evolution response metazoan phylogenesis.
Язык: Английский
Процитировано
7
Zoological Journal of the Linnean Society, Год журнала: 2023, Номер 200(4), С. 980 - 993
Опубликована: Сен. 7, 2023
Abstract The shell of bivalves acts as structural support, defence against predators, stressors, and maintenance homeostasis. Haemocytes mantle epithelial cells participate in formation. Mantle produce the organic matrix are associated with biomineralization because their proximity to surface ability maintain deposition ex vivo. play an immunological role involved Ca2+ CO32- intracellular transport implicated mineralization. This study aims evaluate expression molecules that key roles internal nervous system, haemocytes outer margin two species bivalves, Polititapes aureus Gmelin, 1791 Cerastoderma glaucum Bruguière, 1789, highlight collaborative Our data show for first time presence serotonin/S100 protein, TLR2/iNOS colocalization P. C. glaucum, suggesting perform canonical sensory biomineralizing activity, while typical immune function, collaboration formation, providing new information on cellular interactions formation giving more details taxonomical studies.
Язык: Английский
Процитировано
7
Integrative Organismal Biology, Год журнала: 2022, Номер 4(1)
Опубликована: Янв. 1, 2022
The gastropod shell is a composite composed of minerals and matrix proteins (SMPs). SMPs have been identified by proteomics in many molluscs, but few studied detail. Open questions include (1) what gene regulatory networks regulate SMP expression, (2) roles individual play biomineralization, (3) how the complement changes over development. These are best addressed species which perturbation studies available; one such slipper snail, Crepidula fornicata. Here, SEM pXRD analysis demonstrated that adult C. fornicata exhibits crossed lamellar microstructure aragonite. Using high-throughput we 185 occluded within shell. Over half proteome known biomineralization domains, while at least 10% no homologs public databases. Differential expression 20 genes up-regulated shell-producing mantle tissue. these expressed during development with two, CfSMP1 CfSMP2, exclusively gland. Together, description list now sets stage for studying consequences knockdowns molluscs.
Язык: Английский
Процитировано
6
Current topics in developmental biology/Current Topics in Developmental Biology, Год журнала: 2022, Номер unknown, С. 375 - 399
Опубликована: Янв. 1, 2022
Язык: Английский
Процитировано
5
Genes, Год журнала: 2022, Номер 13(3), С. 454 - 454
Опубликована: Март 2, 2022
The current diversity of metazoans has been achieved through a long process evolution since the appearance their unicellular ancestor about 1000 Mya [...].
Язык: Английский
Процитировано
2