Journal of Clinical Medicine, Год журнала: 2025, Номер 14(5), С. 1482 - 1482

Опубликована: Фев. 23, 2025

Background: In this study, we evaluated the changes in clinicopathological features and prognosis patients with thyroid cancer last two decades using Surveillance, Epidemiology, End Results Database (SEER) data. Methods: Data from SEER-12 registry (1992–2021) were analyzed, focusing on diagnosed malignant between 2001 2020. The study population was divided into Cohort 1 (2001–2010) 2 (2011–2020). Cohorts compared regarding prognosis. Results: included 94,892 2020, 39,265 55,627 2. Compared to 1, showed a statistically significant increase proportion of aged 60+ (+4.2%), male (+2.1%), cases papillary (+5.3%) regional disease (+3.7%) (all p < 0.001). Although demonstrated an 8% improvement survival result not (p = 0.057). Prognostic factors identified, such as stage at diagnosis, age, gender, origin. Among pathological subtypes, + FV had best (HR: 0.78), other group, mainly comprising anaplastic tumors sarcomas, which worst 9.61). Conclusions: large-scale patients, found differences cohorts. 2, ≥60 years, male, increased. We that sex, origin, histopathological subtype, diagnosis prognostic cancer. Also, observed trend toward improved

Язык: Английский