Effects of Behavioral, Clinical, and Policy Interventions in Reducing Human Exposure to Bisphenols and Phthalates: A Scoping Review

Environmental Health Perspectives, Год журнала: 2024, Номер 132(3)

Опубликована: Март 1, 2024

There is growing interest in evidence-based interventions, programs, and policies to mitigate exposures bisphenols phthalates using implementation science frameworks evaluate hypotheses regarding the importance of specific approaches individual or household behavior change institutions adopting interventions.

Язык: Английский

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Lifestyle interventions to reduce endocrine-disrupting phthalate and phenol exposures among reproductive age men and women: A review and future steps

Environment International, Год журнала: 2022, Номер 170, С. 107576 - 107576

Опубликована: Окт. 14, 2022

Non-persistent endocrine-disrupting chemicals (EDCs), including phthalates and phenols, are ubiquitous in both the environment human body. A growing body of epidemiologic studies have identified concerning links between EDCs adverse reproductive developmental health effects. Despite consistent evidence, risk assessments policy interventions often arrive late. This presents an urgent need to identify evidence-based for implementation at clinical community levels reduce EDC exposure, especially susceptible populations. The life cycle (menarche menopause females after pubertal onset males) includes some most vulnerable periods environmental exposures, such as preconception perinatal stages, representing a key window opportunity intervene prevent unfavorable outcomes. review aims synthesize assess behavioral, dietary, residential EDC-driven develop recommendations subsequent, larger-scale that address knowledge-gaps current during cycle. We selected 21 primary evaluation, addition four supplemental interventions. Among these, accessible (web-based) educational resources, targeted replacement (known) toxic products, personalization intervention through meetings support groups, were promising strategies reducing concentrations. However, we document paucity phthalate phenol exposures years, among men. Accordingly, recommend additional, larger community-based exposure. Specifically, future should focus on short-term, mid-, long-term exposure reduction phenols. latter, especially, is required development public guidelines promote globally.

Язык: Английский

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Interventions to Reduce Exposure to Synthetic Phenols and Phthalates from Dietary Intake and Personal Care Products: a Scoping Review

Current Environmental Health Reports, Год журнала: 2023, Номер 10(2), С. 184 - 214

Опубликована: Март 29, 2023

Abstract Purpose of Review A scoping review was conducted to identify interventions that successfully alter biomarker concentrations phenols, glycol ethers, and phthalates resulting from dietary intake personal care product (PCPs) use. Recent Findings Twenty-six in populations ranging children older adults were identified; 11 actively removed or replaced products, 9 provided products containing the chemicals being studied, 6 education-only based interventions. Twelve manipulated only with a focus on bisphenol (BPA) phthalates, 8 studies intervened PCPs use focused wider range including BPA, triclosan, parabens, ultraviolet absorbers, while both diet BPA its alternatives. No assessed ethers. All but five reported results expected direction, removing potential sources exposures lowering EDC providing increasing concentrations. Short lasting few days successful. Barriers intervention success included participant compliance unintentional contamination products. Summary The identified generally successful illustrated influence motivation, compliance, ease adherence, difficulty fully due their ubiquity difficulties identifying “safer” replacement Policy which reduces removes manufacturing processing across multiple sectors, rather than individual behavior change, may have greatest impact population exposure.

Язык: Английский

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Analytical method for the biomonitoring of bisphenols and parabens by liquid chromatography coupled to tandem mass spectrometry in human hair

Ecotoxicology and Environmental Safety, Год журнала: 2022, Номер 243, С. 113986 - 113986

Опубликована: Авг. 24, 2022

Bisphenols and parabens are endocrine disruptors families widely used in daily life. They known to be linked numerous pathologies such as reproductive disorders, obesity, breast cancer, hypertension asthma. Biomonitoring is an essential tool for assessing population exposure environmental pollutants. Blood urine the main matrices human biomonitoring. However, they not suitable evaluate long-term with a short elimination half-life or phenols. Hair appears interesting alternative matrix allowing wide window of due accumulation xenobiotics during hair growth. This study presents development validation high-performance liquid chromatography coupled tandem mass spectrometry simultaneous determination bisphenol A, its chlorinated derivatives, F, S hair. An optimised sample preparation based on acidic hydrolysis followed by liquid-liquid extraction was performed, before analysis ultra-high performance multiple reaction monitoring mode. To validate method, recognized bioanalytical guidelines were calibration quality control samples prepared samples. Linearities over 0.996 whole range concentrations. Trueness precision demonstrated each target analyte intra-day inter-day bias values ranging from 86 % 118 relative standard deviation 0 19 %. At same time, limits quantification set at 0.25 ng/g A parabens, 0.05 bisphenols F 0.00625 derivatives A. reliable method applied taken hospital professionals allowed these this population. Chlorinated quantified here first time.

Язык: Английский

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A Personalized Intervention to Increase Environmental Health Literacy and Readiness to Change in a Northern Nevada Population: Effects of Environmental Chemical Exposure Report-Back

International Journal of Environmental Research and Public Health, Год журнала: 2024, Номер 21(7), С. 905 - 905

Опубликована: Июль 11, 2024

Background: Interventions are needed to help people reduce exposure harmful chemicals from everyday products and lifestyle habits. Report-back of individual exposures is a potential pathway increasing environmental health literacy (EHL) readiness exposures. Objectives: Our objective was determine if report-back endocrine-disrupting (EDCs) can EDC exposure, increase EHL, change (i.e., implement exposure-reduction behaviors). Methods: Participants in the Healthy Nevada Project completed EHL readiness-to-change surveys before (n = 424) after 174) intervention. used mail-in kits measure urinary biomarkers EDCs. The results included levels, information about effects, sources personalized recommendations exposure. Results: generally very high at baseline, especially for questions related general pollution. For chemical exposures, responses varied across several demographics. Statistically reliable improvements were seen report-back. change, 72% already or planning their behaviors. Post-intervention, women increased (p 0.053), while men decreased 0.007). When asked what challenges they faced reducing 79% cited not knowing do. This dropped 35% with higher propylparaben younger 0.03) participants who rated themselves better had levels some phthalates 0.02–0.003 p 0.001–0.003, respectively). After report-back, monobutyl phthalate among 48 valid urine tests intervention < 0.001). Conclusions: successful as evidenced by behaviors, women, decrease phthalate. An questionnaire more sensitive would differentiate low literacy. Future research will focus on understanding why how be improved all participants.

Язык: Английский

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Main Factors Influencing the Perceived Health Risk of Endocrine-Disrupting Chemicals: A Systematic Literature Review

Environmental Research, Год журнала: 2024, Номер 262, С. 119836 - 119836

Опубликована: Авг. 23, 2024

Endocrine-disrupting chemicals (EDCs) are linked to rising health issues such as infertility, childhood obesity, and asthma. While some research exists on risk perceptions of EDCs, a comprehensive understanding across different populations contexts is needed. We performed systematic literature review, examining 45 articles published between 1985 2023, focusing both the perception EDCs whole well individual found in environment (e.g., pesticides, bisphenol A, phthalates). identified four major categories factors influencing EDC perception: sociodemographic (with age, gender, race, education significant determinants), family-related (highlighting increased concerns households with children), cognitive (indicating that knowledge generally led perception), psychosocial trust institutions, worldviews, health-related primary determinants). This review highlights complex nature perception, shaped by sociodemographic, family, cognitive, factors, essential for policymakers crafting educational communication strategies. Future should expand cover more use representative samples, explore influence deeply.

Язык: Английский

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Assessment of Endocrine Disruptor Exposure in Hospital Professionals Using Hair and Urine Analyses: An Awareness Campaign

Therapeutic Drug Monitoring, Год журнала: 2023, Номер unknown

Опубликована: Авг. 8, 2023

Background: In 2021, French public authorities initiated the fourth National Environmental Health Plan to prevent environment-related health risks. This plan primarily focuses on sensitization of professionals and care institutions. Endocrine disruptors (EDs) are environmental factors associated with several adverse effects, such as reproductive disorders, obesity, cancer. study aimed conduct an awareness campaign among at a general hospital center risks related EDs. Methods: Hospital were directly involved in this study, urine hair samples collected determine bisphenol paraben exposure levels. Analyses performed using validated liquid chromatography-tandem mass spectrometry methods, enabling simultaneous determination bisphenols parabens. A questionnaire lifestyle habits was distributed assess its relationship profiles. Nineteen recruited for study. Results: Bisphenol detected 95% samples, chlorinated derivatives between 16% 63%. parabens showed detection frequencies 37% 100%, methylparaben quantified average concentration 0.45 ± 0.46 ng/mL. A, F, S 95%–100%, 37%–68%, 100%. Conclusions: may encourage institutions adopt policy reducing endocrine disruptor their patients professionals, who could be educated regarding Conducting multicenter refine results herein establish dynamic systems would valuable.

Язык: Английский

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Mother’s knowledge for environmental risks and self-awareness for the presence of pollutants in her living area in West and Central Anatolia: a cross-sectional survey

BMC Public Health, Год журнала: 2023, Номер 23(1)

Опубликована: Сен. 14, 2023

Environmental risk awareness is a key concept to raise and plan future programs for environmental protection. A cross-sectional household survey aimed find out the presence of hazards next living area mother's knowledge levels about factors with their related according district development ranking, Western Central Anatolian regions sampling from rural urban residence.The study was designed weighted population density in 2008. Data on demography health status, dwelling characteristics residents are also collected 2009. In addition, open-ended questions "What does risk/hazard mean?" "Which risks/hazards present your environment?" were asked. The data analyzed using multivariate binary logistic regression.The sample included 3489 mothers either or areas. Of mothers, 19.3% did not know what an 75.7% stated that there at least one pollutant environment. most commonly perceived factor air pollution (23.0%), which reported be areas by 12.4%. Regions, residence, settlement features house, status family members associated perception statistically significant level.The neighborhood conditions factors. Communication cooperation between local governments, institutions, non-governmental organizations other stakeholders should strengthened increase awareness.

Язык: Английский

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Main Factors Influencing the Perceived Health Risk of Endocrine-Disrupting Chemicals: A Systematic Literature Review

Опубликована: Май 30, 2024

Endocrine-disrupting chemicals (EDCs) are linked to rising health issues likeinfertility and testicular cancer. Despite the recognized risks, little is known about howpeople perceive risks associated with EDCs. Here we provide a comprehensiveoverview of research on perceived EDCs identify key factors influencingthese perceptions. We performed systematic literature review, examining 45 articlespublished between 1985 2023, focusing both risk perception as awhole well individual found in environment (e.g., pesticides, bisphenol A,and phthalates). identified four major categories influencing EDC riskperception: sociodemographic (with age, gender, race, education significantdeterminants), family-related (highlighting increased concerns households withchildren), cognitive (indicating that knowledge generally led toincreased perception), psychosocial trust institutions, worldviews,and health-related primary determinants). This review highlights complexnature perception, shaped by sociodemographic, family, cognitive, andpsychosocial factors, essential for policymakers crafting educational communicationstrategies. Future should expand cover more EDCs, use representativesamples, explore influence deeply.

Язык: Английский

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Gebe Okulu Eğitimcilerinin Gözüyle Endokrin Bozucular: Nitel Bir Çalışma

Journal of Midwifery and Health Sciences, Год журнала: 2024, Номер 7(2), С. 317 - 326

Опубликована: Июль 5, 2024

Amaç: Bu araştırmanın amacı gebe okulu programlarında eğitimci olarak görev alan ebe ve hemşirelerin endokrin bozucular konusundaki bilgi tutumlarını incelemektir. Yöntem: Fenomenolojik tipte tasarlanan evreni, İstanbul ilindeki yapan 44 ebe/hemşireden oluşmuştur (N=44). Ölçüt örnekleme yöntemi kullanılarak örneklem veri doygunluğu takip edilmiş doygunluk sağlandığında toplama işlemi tamamlanmıştır (n=7). 13 Eylül 2021 tarihinde yapılan araştırmada, veriler odak grup ile araştırmacılar tarafından oluşturulan yarı yapılandırılmış görüşme formuyla toplanmıştır. Nicel veriler, tanımlayıcı istatistiksel analizler kullanılarak, nitel ise içerik analiziyle değerlendirilmiştir. Bulgular: Ebe görüşme formuna verdikleri cevaplar doğrultusunda; bozucuların önemi, bilgisi, farkındalığı oluşturma eğitimine entegrasyon şeklinde dört adet tema oluşturulmuştur. Prenatal dönem eğiticilerinin öneminin farkında olmalarına rağmen konu hakkındaki bilgilerinin yetersiz olduğu belirlenmiştir. Ayrıca katılımcıların konunun prenatal eğitimlerde yer alması farkındalık geliştirilebilmesi için çeşitli önerilerinin bulunduğu saptanmıştır. Sonuç: bozuculara yönelik çok fazla olmadığı hatta kısmen yanlış bilgilere sahip oldukları görülmüştür. Eğitici eğitimlerinin içeriğine bozucularla ilgili konuların eklenerek bilinçlendirme çalışmalarının arttırılması gerektiği sonucuna varılmıştır.

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