Cardiovascular risk factors and kidney function among automobile mechanic and their association with serum heavy metals in Southwest Nigeria: A cross-sectional study

PLoS ONE, Год журнала: 2023, Номер 18(10), С. e0292364 - e0292364

Опубликована: Окт. 11, 2023

Introduction The burden of cardiovascular disease (CVD) is huge due to its associated morbidity, mortality and adverse socio-economic impact. Environmental pollution as a risk factor contributes significantly the CVD, especially in low middle income countries. One effective strategies reduce CVD prevent or detect factors early at-risk population. This study determined some factors, kidney function, their association with heavy metals among automobile mechanics. Method was cross-sectional involving 162 mechanics 81 age sex matched controls. Serum levels lead, cadmium risks were assessed compared two groups. Associations between serum using correlation analysis. P value <0.05 taken significant. Results mean ages controls 47.27±9.99 years 48.94±10.34 years, respectively. prevalence elevated higher (25.9% vs 7.9%; p = <0.001). significant total cholesterol (32.1% 18.5%; 0.017), hyperuricemia (20.4% 1.2%; <0.001), blood glucose (16.0% 4.9% 0.013); alcohol use (55.1% 30.0%; 0.001). Among mechanics, there positive correlations cadmium, atherogenic index plasma (AIP) (p 0.024; r 0.382) triglyceride 0.020; 0.391). Significant found lead neutrophil gelatinase lipocalin (NGAL) <0.001; 0.329). There level, AIP 0.016; 0.373) TG 0.004; 0.439); NGAL all participants 0.005; 0.206). Conclusion Automobile have notable exposure factors. Health education sensitisation well policies that would regulate persons should be implemented Nigeria.

Язык: Английский

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Associations of per- and polyfluoroalkyl substances and heavy metals with blood lipid profiles in a representative sample of Korean adolescents

Environmental Health, Год журнала: 2024, Номер 23(1)

Опубликована: Ноя. 22, 2024

Abstract Background Previous studies on the associations of per- and polyfluoroalkyl substances (PFASs) heavy metals with lipid profiles among adolescents have been scarce. We sought to investigate PFASs blood levels in a representative sample Korean adolescents. Methods Data from National Environmental Health Survey (2018–2020) were used. Concentrations [perfluorooctanoic acid (PFOA), perfluorooctane sulfonic (PFOS), perfluorohexane acid, perfluorononanoic (PFNA), perfluorodecanoic (PFDeA)], lead, mercury measured serum, whole blood, urine samples, respectively. Linear regression, Bayesian kernel machine regression (BKMR), k-means clustering analyses employed evaluate between pollutants levels. Results In linear analyses, PFOA associated higher low-density lipoprotein cholesterol (LDL-C) levels; PFOS total (TC) PFNA TC, LDL-C, non-high-density (non-HDL-C) PFDeA non-HDL-C, high-density TC non-HDL-C The BKMR analysis revealed that PFAS metal mixture was LDL-C (1.8% increase at 75th percentile all concentrations compared their median values, 95% credible interval: 0.5, 3.1), primarily driven by effect PFDeA. Compared individuals low pollutant exposure cluster (geometric mean PFOA, PFOS, PFHxS, PFNA, PFDeA, 2.7 μg/L, 6.2 1.6 0.7 0.4 0.8 μg/dL, 0.3 respectively), those high (5.1 10.7 3.7 1.3 0.6 0.9 respectively) demonstrated (2.5% confidence 0.1, 5.0) analysis. Conclusion Due limitations this study, such as its cross-sectional design, these results should be interpreted cautiously confirmed future before drawing implications for public health strategies aimed promoting during adolescence later life.

Язык: Английский

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Dose-response relationship of elements with blood lipids and the potential interaction: A cross-sectional study from four areas with different pollution levels in China

Journal of Trace Elements in Medicine and Biology, Год журнала: 2023, Номер 79, С. 127206 - 127206

Опубликована: Май 17, 2023

Язык: Английский

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Association between urinary cadmium level and subclinical myocardial injury in the general population without cardiovascular disease aged ≥ 50 years

Environmental Science and Pollution Research, Год журнала: 2023, Номер 30(31), С. 77551 - 77559

Опубликована: Июнь 1, 2023

Язык: Английский

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Association Between Multiple Metal(loid)s Exposure and Blood Lipid Levels: Evidence from a Cross-Sectional Study of Southeastern China

Biological Trace Element Research, Год журнала: 2023, Номер 202(8), С. 3483 - 3495

Опубликована: Ноя. 22, 2023

Язык: Английский

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