The Effectiveness of Nonpharmacological Interventions in the Management of Chemotherapy Physical Side Effects: A Systematic Review
Healthcare,
Год журнала:
2024,
Номер
12(18), С. 1880 - 1880
Опубликована: Сен. 19, 2024
Despite
advancements
in
cancer
treatment,
chemotherapy
side
effects
significantly
impact
patients
both
physically
and
emotionally.
While
pharmacological
treatments
can
mitigate
these
effects,
they
may
trigger
additional
exacerbating
the
overall
discomfort
experienced
by
patients;
moreover,
psychological
factors
influencing
physical
symptoms
are
beyond
reach
of
interventions.
Nonpharmacological
interventions,
however,
offer
potential
for
complementary
or
alternative
solutions.
This
review
aims
to
a
comprehensive
analysis
literature
on
effectiveness
nonpharmacological
interventions
managing
chemotherapy.
review,
based
search
PubMed,
PsycINFO,
Web
Science
databases,
identified
46
relevant
studies.
It
categorizes
evaluates
their
common
(fatigue,
nausea,
pain,
diarrhea,
constipation).
Guided
imagery,
tailored
exercises,
Qigong
show
promise
reducing
fatigue,
while
like
yoga
cognitive-behavioral
approaches
address
nausea
vomiting.
Pain
benefits
result
from
guided
imagery
educational
Limited
evidence
exists
diarrhea
constipation
necessitating
further
research.
offers
provisional
conclusions,
emphasizing
integrating
evidence-based
alongside
enhance
patient
outcomes
reduce
chemotherapy-induced
considering
such
as
accessibility,
safety,
customization,
adaptability
clinical
settings.
Язык: Английский
Neoadjuvant Chemotherapy Is Effective in Those Infected With SARS-CoV-2: The Real-World Experience of a Large Chinese Breast Cancer Center
Journal of Breast Cancer,
Год журнала:
2024,
Номер
27(3), С. 176 - 176
Опубликована: Янв. 1, 2024
During
the
major
shift
in
China's
policies
on
coronavirus
disease
2019
(COVID-19),
many
residents
will
be
infected
with
severe
acute
respiratory
syndrome
2
(SARS-CoV-2)
over
a
short
period,
including
few
patients
breast
cancer
undergoing
neoadjuvant
chemotherapy
(NAC).
Moreover,
it
is
unknown
whether
this
comorbidity
affects
efficacy
of
NAC
for
and
patient's
psychological
state
quality
life
(QOL).
This
study
aims
to
answer
these
questions.
Язык: Английский
Impact of the COVID-19 Pandemic on Tumor Stage and Pathohistological Parameters of Vulvar Cancer
Journal of Clinical Medicine,
Год журнала:
2024,
Номер
13(14), С. 4058 - 4058
Опубликована: Июль 11, 2024
Background/Objectives:
Vulvar
cancer
(VC)
comprises
a
small
fraction
of
female
neoplasms
with
notable
high-incidence
clusters
among
German
regions.
Despite
proposed
impact
nationwide
lockdowns
in
response
to
the
COVID-19
pandemic
on
oncological
diseases,
effect
VC
staging
and
tumor
characteristics
remains
yet
be
resolved;
therefore,
analyzing
pathological
data
from
patients
squamous
cell
pre-,
during,
post-COVID
region
may
offer
insights
into
potential
epidemiological
clinical
trends.
Methods:
We
identified
total
90
who
were
diagnosed
at
Institute
Pathology,
University
Hospital
Saarland,
between
2018
2023,
defined
three
distinct
cohorts:
pre-COVID
cohort
(2018-2019),
COVID
(2020-2021),
(2022-2023).
Histomorphological
collected
individual
patient
reports
statistically
analyzed
using
Fisher's
exact
test
or
Kruskal-Wallis
test.
Results:
Although
we
found
no
significant
differences
age,
T-stage,
perineural
infiltration,
blood
vessel
resection
status,
grading,
margin
our
cohorts,
surprisingly,
determined
greater
extent
lymphovascular
infiltration
(Fisher's
test;
p
=
0.041),
as
well
deeper
depth
(Kruskal-Wallis
<
0.001)
before
pandemic.
Furthermore,
did
not
identify
any
soft
indications
abnormalities
care
within
center
(unchanged
status
margins
across
all
cohorts).
Conclusions:
Our
results
clearly
do
support
negative
affection
pathobiological
during
after
However,
final
assessments
regarding
pandemic's
require
additional
study
approaches
various
regions,
preferably
future
extended
timeframes
longer
follow-up.
Язык: Английский