Sensing methods for stress biomarker detection in human saliva: a new frontier for wearable electronics and biosensing

Materials Advances, Год журнала: 2024, Номер 5(13), С. 5339 - 5350

Опубликована: Янв. 1, 2024

The development of sensitive and reliable saliva based biosensing technologies in the form smart dentures holds potential to revolutionize physical cognitive stress research.

Язык: Английский

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Differences in Heart Rate Variability in the Frequency Domain between Different Groups of Patients

Medicina, Год журнала: 2024, Номер 60(6), С. 900 - 900

Опубликована: Май 29, 2024

Background and Objectives: Heart rate variability (HRV) is defined as a physiological variation in duration between sinus beats. The aim of this study was to research analyze the HRV various groups patients. Materials Methods: A retrospective conducted an outpatient setting. Patients who had undergone tilt-table test were selected for divided into three based on their self-reported health anamnesis: group 1 (n = 84, mean age 45.8 ± 17.8) consisted patients with no known orthostatic intolerance or neurodegenerative disease, 2 suspected 50, 46.5 18.6), 3 disorder 29, 55.6 20.4). During test, frequency-domain parameters—normalized low frequency (LFnu) high (HFnu), absolute powers—absolute (LF-RRI), (HF-RRI), LF/HF ratio—were recorded during 5 min rest supine position. Results: Group reduced LFnu at 52.93% (SD: 18.00) compared 58.57% (18.06) 61.80% 17.74), increased HFnu: 1—47.08% 17.97), 2—41.41% 18.03), 3—38.16% 14.7). HFnu differences statistically significant (p < 0.05). LF-RRI reported follows: 1—531.32 ms2 578.57), 2—346.2 447.96), 3—143.21 166.96). HF-RRI 1—835.87 1625.42), 2—297.46 507.15), 3—70.83 75.67). comparisons 0.001). ratios 1—1.91 2.29), 2—2.43 2.33), 3–2.54 2.17). ratio p 0.05. Conclusions: This shows that disorders have HRV, possibly caused by parasympathetic modulation. more severely than disorders. Other studies indicated possible increase risk cardiovascular therefore, analysis could be potential clinical diagnostic tool. However, lack universally agreed upon methodology, reference values, external internal factor influence hinders introduction examinations wider practice.

Язык: Английский

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Recent Advances in the Wearable Devices for Monitoring and Management of Heart Failure

Reviews in Cardiovascular Medicine, Год журнала: 2024, Номер 25(10)

Опубликована: Окт. 28, 2024

Heart failure (HF) is an acute and degenerative condition with high morbidity mortality rates. Early diagnosis treatment of HF can significantly enhance patient outcomes through admission readmission reduction improve quality life. Being a progressive condition, the continuous monitoring vital signs symptoms patients to identify any deterioration customize regimens be beneficial management this disease. Recent breakthroughs in wearable technology have revolutionized landscape management. Despite potential benefits, integration devices into requires careful consideration technical, clinical, ethical challenges, such as performance, regulatory requirements data privacy. This review summarizes current evidence on role heart management, discusses challenges opportunities field.

Язык: Английский

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Disorders of circadian rhythms of heart rate variability in diabetic cardiac autonomic neuropathy: mechanisms and consequences

INTERNATIONAL JOURNAL OF ENDOCRINOLOGY (Ukraine), Год журнала: 2025, Номер 20(8), С. 549 - 558

Опубликована: Янв. 4, 2025

Abnormalities in heart rate variability (HRV) may increase the risk of cardiovascular disease over next six years from 4 to 10 %. It is reported that probability stroke or cardiac death can be immediately reduced by chronobiologically assessing HRV and optimizing timed treatment efficacy. Physiological activities are under control autonomic nervous system. Damage nerves results dysfunction vascular dynamics, particularly neuropathy (CAN). Autonomic imbalance sympathetic (SNS) parasympathetic systems (PSNS) regulation function contributes metabolic abnormalities significant morbidity mortality for individuals with diabetes mellitus (DM). Misalignment circadian rhythms has been evidenced patients DM, there a close relationship between alterations neuroendocrine sleep architecture, clock oscillations, glucose metabolism, function, diurnal profiles blood pressure rate. Metabolic syndrome, hypertension, myocardial infarction, DM characterized increased SNS activity decreased PSNS activity. However, type 2 had decrease both explained which responsible CAN affects fibers. The purpose this review was discuss current state problem rhythm disorders, HRV. Particular attention paid factors diabetic CAN; insights into mechanisms excess associated pathogenesis possible pathogenic pathways binding atherosclerosis progression; genetic epigenetic HRV; disorders. search conducted Scopus, Science Direct (from Else­vier), PubMed, including MEDLINE databases. keywords used were mellitus, neuropathy, rhythms, variability. A manual bibliography publications identify study could not found during online search.

Язык: Английский

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Tracking changes in autonomic function by coupled analysis of wavelet-based dispersion of heart rate variability and gastrointestinal symptom severity in individuals with hypermobile Ehlers–Danlos syndrome

Frontiers in Neurology, Год журнала: 2025, Номер 15

Опубликована: Янв. 15, 2025

People with hypermobile Ehlers-Danlos syndrome (hEDS) experience multisystemic dysfunction varying severity and unpredictability of flare occurrence. Cohort studies suggest that individuals hEDS have a higher risk for autonomic dysfunction. The gold standard assessing function, clinically, is the heart rate variability (HRV) assessment from 24-h Holter monitor electrocardiogram data, but this expensive can only be performed in short durations. Since their advent, biometric devices been non-invasive method tracking HRV to assess function. This study aimed understand intra- inter-individual function associate gastrointestinal symptoms using wearable devices. We studied 122 days device data 26 individuals, including 35 highlighted as high (GI) 48 low GI Utilizing wavelet analysis frequency domains signals, we compared participants' high, low, very (VLF), ultralow (ULF) associated physiological differences. found significant difference between VLF ULF signals on high-GI symptom low-symptoms 92 76% sampled, respectively. Our pilot show change experiencing day single-body system. Future research will focus evaluating relationship longitudinal fluctuations HRV.

Язык: Английский

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A new metric to understand the association between heart rate variability and menstrual regularity

npj Digital Medicine, Год журнала: 2025, Номер 8(1)

Опубликована: Фев. 24, 2025

Cardiovascular disease is underdiagnosed and undertreated in women compared to men. Wearable technologies (wearables) help shed light on women's cardiovascular by collecting continuous data correlating it with hormonal fluctuations across the menstrual cycle. In this context, Jasinski et al. propose that new metric, amplitude, enables non-invasive monitoring of female physiology health

Язык: Английский

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Feasibility of Remote Intensive Monitoring: A Novel Approach to Reduce Black Postpartum Maternal Cardiovascular Complications

Journal of Midwifery & Women s Health, Год журнала: 2025, Номер unknown

Опубликована: Фев. 26, 2025

Approximately 53% of maternal mortality occurs in the postpartum period, a time with little monitoring and health surveillance. The objective this study was to test feasibility, usability, appropriateness, acceptability remote low-burden physiologic Black women, using novel soft wearable patch home vital sign for first 4 weeks postpartum. A prospective longitudinal cohort feasibility 20 women conducted equipment sensors measuring temperature, pulse oximetry, blood pressure, electrocardiogram (ECG), heart rate, respiration twice daily during Feasibility, acceptability, usability were measured at end Feasibility Intervention Measure, Acceptability Appropriateness System Usability Scale. Twenty recruited consented participate study. Remote rated as feasible (93%), acceptable appropriate (92%), useable (80%). During 2 postpartum, detected that 60% had pressures exceeding 140/90 mm Hg. provided data on ECG, rate variability, temperature. Our research suggests has potential identify risk complications.

Язык: Английский

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Current and future role of biomarkers in the monitoring and prognosis of coronary artery disease

Future Cardiology, Год журнала: 2025, Номер unknown, С. 1 - 3

Опубликована: Март 10, 2025

KEYWORDS: Coronary artery diaseasebiomarkerslimitationsmachine learningexosomescombined panel of biomarkers

Язык: Английский

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A Scoping Review of Studies Reporting Heart Rate Variability Measurement Among Pregnant and Postpartum People Using Wearable Technology

Biological Research For Nursing, Год журнала: 2025, Номер unknown

Опубликована: Март 24, 2025

Maternal mental health conditions significantly contribute to pregnancy-related mortality in the United States. Approximately 20–25% of postnatal women exhibit symptoms depressive and anxiety disorders. Mental is influenced by stress, which affects mood, cognition, behavior. Heart rate variability (HRV), time interval between consecutive heartbeats, a physiological marker for assessing stress levels, providing critical insights into body’s autonomic responses. Wearable devices measuring HRV offer non-invasive method monitor health, enabling early detection maternal dynamics facilitate timely interventions. In this scoping review, we aimed capture current state science on two areas focus: (1) utilization wearable technology monitoring pregnant postpartum women, (2) findings from these perinatal studies, including observed trends throughout pregnancy postpartum, as well association HRV, health. The six included studies employed five fitness tracking wearables, utilizing either periodic or continuous 24-h monitoring. Findings include evidence that declines during pregnancy, with return normal levels postpartum. Associations were inconsistent across some demonstrating correlations others reporting no relationship. Postpartum measurements effectively differentiated depression (PPD) versus those adjustment disorder (AJD), high diagnostic accuracy. shows promise biomarker among pregnant/postpartum people, although more work needed standardize optimal methods measurement population.

Язык: Английский

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Prediction of perioperative complications in colorectal cancer via artificial intelligence analysis of heart rate variability

World Journal of Gastrointestinal Surgery, Год журнала: 2025, Номер 17(4)

Опубликована: Март 29, 2025

BACKGROUND Heart rate variability (HRV) represents efferent vagus nerve activity, which is suggested to be related fundamental mechanisms of tumorigenesis and a predictor prognosis in various cancers. Therefore, this study hypothesized that HRV monitoring could predict perioperative complication (PC) colorectal cancer (CRC) patients. AIM To investigate the prognostic value hospitalized CRC METHODS The observational studies included 87 patients who underwent surgical procedures under enhanced recovery after surgery programs first-class hospital. parameters were compared between PC group non (NPC) from preoperative day 1 postoperative (Pod) 3. In addition, inflammatory biomarkers nutritional indicators also analyzed. RESULTS was 14.9%. markedly abnormal surgery, especially group. frequency-domain (including pNN50) time-domain [including high-frequency (HF)] significantly different two groups postoperatively. pNN50 greater at Pod1 than NPC returned baseline Pod2, suggesting with complications exhibited autonomic dysfunction early period. group, HFs higher group; elevated Pod2 Pod3; levels lower Pod2; white blood cell count slightly Pod3. CONCLUSION independently associated CRC. Abnormal predicted an increased risk Continuous used monitor during

Язык: Английский

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