Urine Metabolomic Patterns to Discriminate the Burnout Levels and Night-Shift-Related Stress in Healthcare Professionals
Metabolites,
Год журнала:
2025,
Номер
15(4), С. 273 - 273
Опубликована: Апрель 14, 2025
Burnout
syndrome,
which
significantly
impacts
both
individual
and
societal
quality
of
life,
is
primarily
characterized
by
three
key
criteria:
depersonalization,
emotional
exhaustion,
low
personal
accomplishment,
all
linked
to
work-related
stress.
Purpose:
Comparative
evaluation
urine
metabolite
patterns
that
may
discriminate
the
burnout
levels
effects
night
shifts
on
healthcare
professionals.
The
Maslach
Inventory
survey
was
administered
64
physicians
nurses
working
day
shifts,
with
scores
for
each
criterion
recorded.
Methods:
Urine
samples
were
collected,
metabolomic
analyzed
using
UHPLC-QTOF-ESI+-MS
technology.
This
analysis
employed
untargeted
semi-targeted
metabolomics,
coupled
multivariate
ANOVA
statistics,
utilizing
online
Metaboanalyst
6.0
platform.
Partial
Least
Squares
Discriminant
Analysis
(PLSDA)
performed,
along
VIP
values,
Random
Forest
graphs,
heatmaps
based
79
identified
metabolites.
These
further
complemented
biomarker
(AUC
ranking)
pathway
metabolic
networks.
Results:
findings
highlighted
biochemical
their
correlation
from
dimension.
Conclusions:
study
demonstrated
involvement
major
pathways
in
diagnosing
burnout:
lipid
metabolism,
particularly
related
steroid
hormones
(cortisol,
cortisone,
androsterone
metabolites);
energetic
involving
long-chain
acylated
carnitines
as
transporters
free
fatty
acids,
play
a
role
control;
third
affecting
catecholamine
metabolism
(neurotransmitters
derived
tyrosine,
such
dopamine,
adrenaline,
noradrenaline),
well
tryptophan
(serotonin
melatonin
metabolites)
amino
acid
(including
aspartate,
arginine,
valine).
Язык: Английский
Predicting nursing students’ behavioral intentions to use AI: The interplay of ethical awareness, digital literacy, moral sensitivity, attitude, self-efficacy, anxiety, and social influence
Journal of Human Behavior in the Social Environment,
Год журнала:
2025,
Номер
unknown, С. 1 - 21
Опубликована: Март 3, 2025
Язык: Английский
The Effects of Grit, Emergency Nursing Competency, and Positive Nursing Organisational Culture on Burnout Among Nurses in the Emergency Department
Behavioral Sciences,
Год журнала:
2025,
Номер
15(4), С. 486 - 486
Опубликована: Апрель 8, 2025
This
descriptive
cross-sectional
study
investigated
the
relationship
between
grit,
emergency
nursing
competency,
positive
organisational
culture,
and
burnout
among
department
nurses
identified
factors
influencing
burnout.
The
participants
were
176
from
one
tertiary
six
general
hospitals
in
Chungcheong-do,
South
Korea.
Data
collected
18
July
to
10
August
2024
analysed
using
hierarchical
multiple
regression.
Burnout
was
negatively
correlated
with
grit
(r
=
−0.57,
p
<
0.001),
competency
−0.41,
culture
−0.60,
0.001).
It
also
subdomains
of
culture:
active
leadership
nurse
managers
−0.46,
pursuit
shared
values
−0.55,
trust-based
formation
−0.62,
fair
management
systems
regression
analysis
showed
two
variables
that
significantly
affected
burnout—trust-based
(β
−0.31,
0.012)
−0.29,
0.001);
their
explanatory
power
44.0%
(F
18.19,
Thus,
major
affecting
Therefore,
prevent
effectively
manage
nurses,
organisations
must
create
a
atmosphere
based
on
mutual
respect
trust,
promoting
participation
work,
decision-making,
collaboration.
Язык: Английский