Endocrine-Disrupting Compounds: An Overview on Their Occurrence in the Aquatic Environment and Human Exposure

Water, Год журнала: 2021, Номер 13(10), С. 1347 - 1347

Опубликована: Май 12, 2021

Endocrine-disrupting compounds (EDCs) as emerging contaminants have accumulated in the aquatic environment at concentration levels that been determined to be significant humans and animals. Several belong this family, from natural substances (hormones such estrone, 17-estradiol, estriol) synthetic chemicals, especially pesticides, pharmaceuticals, plastic-derived (phthalates, bisphenol A). In review, we discuss recent works regarding EDC occurrence compartment, strengths limitations of current analytical methods used for their detection, treatment technologies removal water, health issues they can trigger humans. Nowadays, many EDCs identified amounts different water matrices including drinking thus increasing possibility entering food chain. studies correlate human exposure high concentrations with serious effects infertility, thyroid dysfunction, early puberty, endometriosis, diabetes, obesity. Although our intention is not explain all disorders related exposure, review aims guide future research towards a deeper knowledge EDCs’ contamination accumulation highlighting toxicity risks

Язык: Английский

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PFAS: forever chemicals—persistent, bioaccumulative and mobile. Reviewing the status and the need for their phase out and remediation of contaminated sites

Environmental Sciences Europe, Год журнала: 2023, Номер 35(1)

Опубликована: Март 23, 2023

Abstract Background Per- and polyfluorinated alkyl substances (PFAS) have received increasing scientific political attention in recent years. Several thousand commercially produced compounds are used numerous products technical processes. Due to their extreme persistence the environment, humans all other life forms are, therefore, increasingly exposed these substances. In following review, PFAS will be examined comprehensively. Results The best studied carboxylic sulfonic acids with chain lengths of C4 C14, particularly perfluorooctanoic acid (PFOA) perfluorooctane (PFOS). These harmful aquatic fauna, insects, amphibians at concentrations a few µg/L or less, accumulate organisms, biomagnify food webs. Humans, as final link chains, subjected uptake primarily through drinking water. multiple toxic effects, affecting liver, kidney, thyroid, immune system. latter effect is basis for establishment tolerable weekly dose only 4.4 ng/kg body weight sum four representatives PFOA, PFOS, perfluorononanoic (PFNA) perfluorohexane (PFHxS) by European Food Safety Authority (EFSA) 2020. Exposure estimates human biomonitoring show that this value frequently reached, many cases exceeded. major challenge analysis, especially waste: single-substance analyses capture fragment large, diverse family PFAS. As consequence, parameters gained importance. high mobility per makes soil groundwater pollution contaminated sites problem. general, short-chain more mobile than long-chain ones. Processes purification water treatment often ineffective expensive. Recycling PFAS-containing such paper packaging leads carryover contaminants. Incineration requires temperatures completely destroy After PFOS perfluorinated were regulated internationally, manufacturers users switched PFAS: representatives, per- oxo acids, telomeric alcohols acids. Analytical studies an increase environmental chemicals. Ultra-short (chain length C1–C3) not been well studied. Among others, trifluoroacetic (TFA) present globally rapidly concentrations. Conclusions substitution individual recognized hazardous possibly equally virtually unknown chronic toxicity can, solution. answer switch fluorine-free alternatives applications which essential.

Язык: Английский

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Emerging disinfection byproducts: A review on their occurrence and control in drinking water treatment processes

Chemosphere, Год журнала: 2020, Номер 259, С. 127476 - 127476

Опубликована: Июль 1, 2020

Язык: Английский

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Biochar production, activation and adsorptive applications: a review

Environmental Chemistry Letters, Год журнала: 2021, Номер 19(3), С. 2237 - 2259

Опубликована: Фев. 17, 2021

Язык: Английский

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Adsorption performance of modified agricultural waste materials for removal of emerging micro-contaminant bisphenol A: A comprehensive review

The Science of The Total Environment, Год журнала: 2021, Номер 780, С. 146629 - 146629

Опубликована: Март 20, 2021

Язык: Английский

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A nationwide study of occurrence and exposure assessment of neonicotinoid insecticides and their metabolites in drinking water of China

Water Research, Год журнала: 2020, Номер 189, С. 116630 - 116630

Опубликована: Ноя. 10, 2020

Язык: Английский

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Endocrine Disruptors Acting on Estrogen and Androgen Pathways Cause Reproductive Disorders through Multiple Mechanisms: A Review

International Journal of Environmental Research and Public Health, Год журнала: 2021, Номер 18(4), С. 1464 - 1464

Опубликована: Фев. 4, 2021

Increasing contamination of the environment by toxic compounds such as endocrine disrupting chemicals (EDCs) is one major causes reproductive defects in both sexes. Estrogen/androgen pathways are utmost importance gonadal development, determination secondary sex characteristics and gametogenesis. Most EDCs mediate their action through respective receptors and/or downstream signaling. The purpose this review to highlight mechanism which can trigger antagonistic or agonistic response, acting estrogen/androgen causing that lead infertility. In vitro, vivo silico studies focusing on impact related proteins published last decade were considered for review. PUBMED PUBCHEM used literature search. bind estrogen (ERα ERβ) androgen activate alternative G protein-coupled (GPCR), GPR30, estrogen-related receptor (ERRγ) signaling via kinases. Bisphenol A, dichlorodiphenyltrichloroethane, dichlorodiphenyldichloroethylene, polychlorinated biphenyls phthalates toxicants interfere with normal leading infertility sexes many ways, including DNA damage spermatozoids, altered methylation pattern, histone modifications miRNA expression.

Язык: Английский

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Graphene oxide synthesis and applications in emerging contaminant removal: a comprehensive review

Environmental Sciences Europe, Год журнала: 2024, Номер 36(1)

Опубликована: Янв. 20, 2024

Язык: Английский

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Water a major source of endocrine-disrupting chemicals: An overview on the occurrence, implications on human health and bioremediation strategies

Environmental Research, Год журнала: 2023, Номер 231, С. 116097 - 116097

Опубликована: Май 12, 2023

Язык: Английский

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Present status of insecticide impacts and eco-friendly approaches for remediation-a review

Environmental Research, Год журнала: 2023, Номер 240, С. 117432 - 117432

Опубликована: Окт. 20, 2023

Язык: Английский

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