Chemical Engineering Journal, Год журнала: 2023, Номер 470, С. 143986 - 143986
Опубликована: Июнь 7, 2023
Язык: Английский
The Journal of Microbiology, Год журнала: 2024, Номер 62(3), С. 181 - 199
Опубликована: Март 1, 2024
Язык: Английский
Процитировано
9
Surgeries, Год журнала: 2024, Номер 5(3), С. 640 - 659
Опубликована: Авг. 9, 2024
The skin is crucial for homeostasis and body defense, requiring quick healing to maintain internal balance. Initially used bone repair, calcium hydroxyapatite (HAp) now being studied soft tissue engineering. This literature review investigated HAp’s role in repair through searches on PubMed, Scopus (Elsevier), Science Direct, Springer Link, Google Scholar databases without time restrictions, using keywords “hydroxyapatite AND wound” repair”. Inclusion criteria encompassed vivo studies humans animals, English publications, full access, sufficient data repair. Exclusions included duplicates, unrelated articles, editor letters, reviews, comments, conference abstracts, dissertations, theses. Out of the 472 articles initially identified, 139 met inclusion criteria, with 21 focusing HAp Findings indicate that nano-HAp regeneration are promising, especially when combined other biomaterials, offering antimicrobial anti-inflammatory benefits stimulating angiogenesis. suggests their potential application dermatology, surgery, dentistry, extending versatility from hard tissues enhancing critical properties accelerating healing.
Язык: Английский
Процитировано
8
Archives of Dermatological Research, Год журнала: 2025, Номер 317(1)
Опубликована: Янв. 16, 2025
Язык: Английский
Процитировано
1
Archives of Microbiology, Год журнала: 2025, Номер 207(3)
Опубликована: Фев. 23, 2025
Язык: Английский
Процитировано
1
International Journal of Dermatology, Год журнала: 2025, Номер unknown
Опубликована: Март 10, 2025
ABSTRACT The concept of aging has evolved from being primarily attributed to genetic factors recognizing the critical role epigenetic mechanisms. Recent advancements, such as clocks, have provided tools assess biological age and offer insights into processes at molecular level. In aesthetic dermatology, understanding these allows for more personalized, effective interventions targeting root causes skin aging. This review explores interplay changes, aging, potential personalized care enhance longevity rejuvenation. is based on an extensive literature search conducted across PubMed other scientific databases. Studies focused mechanisms DNA methylation, histone modifications, their relationship Particular attention was given recent advancements in including Horvath's Clock GrimAge, implications dermatological treatments. Epigenetic Clock, demonstrated utility assessing through methylation markers, revealing actionable processes. Energy‐based devices like fractional lasers radiofrequency shown promise reversing age‐related promoting collagen synthesis, reducing age. Additionally, lifestyle diet, sleep, circadian rhythm alignment significantly influence health. Integrating dermatology represents a paradigm shift rejuvenation, allowing treatments that address visible signs underlying Using clocks provides framework tailoring individual patient needs, optimizing outcomes, extending results. Future research should focus longitudinal studies, accessibility, ethical considerations fully harness epigenetics health overall well‐being.
Язык: Английский
Процитировано
1
Nutrients, Год журнала: 2023, Номер 15(13), С. 2842 - 2842
Опубликована: Июнь 22, 2023
The human skin is a crucial organ that protects the organism from outer environment. Skin integrity and health depend on both extrinsic intrinsic factors. Intrinsic factors such as aging genetic background contribute to weakened disease susceptibility. Meanwhile, including UV radiation, pollution, smoking, humidity, poor diet also affect disease. On other hand, healthy dietary patterns plant-based diets have gained popularity complementary therapy for health. A defined all based plant foods, an abundance of vegetables, fruits, beans, lentils, legumes, nuts, seeds, fungi, whole grains, with limited or no animal products processed foods. However, some authors exclude limit foods in definition. Recent research has shown these beneficial effects inflammatory diseases. This review explored diseases functional skin. In conclusion, may through gut microbiome.
Язык: Английский
Процитировано
22
Microorganisms, Год журнала: 2023, Номер 11(8), С. 1899 - 1899
Опубликована: Июль 27, 2023
Bioprospecting is the discovery and exploration of biological diversity found within organisms, genetic elements or produced compounds with prospective commercial therapeutic applications. The human skin an ecological niche which harbours a rich compositional microbiome stemming from multifactorial interactions between host microbiota facilitated by exploitable effector compounds. Advances in understanding microbial colonisation mechanisms alongside species strain have revealed novel chemical displays applicative potential. Studies elucidating organismal interfaces concomitant central processes biology begun to unravel potential wealth molecules can exploited for their proposed functions. A variety skin-microbiome-derived display applications, ranging antioncogenic agents relevant cancer therapy treatment strategies antimicrobial-resistant bacterial fungal infections. Considerable opportunities emerged translation personal care products, such as topical mitigate various conditions acne eczema. Adjacent compound developments focused on cosmetic applications reducing ageing its associated changes properties microbiome. contains applications; however, considerable work required vitro findings vivo models ensure translatability.
Язык: Английский
Процитировано
22
Antibiotics, Год журнала: 2023, Номер 12(12), С. 1698 - 1698
Опубликована: Дек. 4, 2023
The skin microbiome is crucial in maintaining health, and its disruption associated with various diseases. Prebiotics are non-digestible fibers compounds found certain foods that promote the activity growth of beneficial bacteria gut or skin. On other hand, live microorganisms, known as probiotics, benefit sustaining healthy conditions when consumed reasonable quantities. They differ from postbiotics, which by-product release same effects their parent bacteria. human vital it comes to health preventing a variety dermatological conditions. This review explores novel strategies use microbiome-targeted treatments maintain enhance overall while managing disorders. It important understand dynamic relationship between these microorganisms diverse microbial communities present on create effective for using probiotics understanding can help optimize formulations treatment regimens improved outcomes skincare, particularly developing solutions problems.
Язык: Английский
Процитировано
19
Pharmaceutics, Год журнала: 2024, Номер 16(6), С. 817 - 817
Опубликована: Июнь 16, 2024
Skin is the largest organ and a multifunctional interface between body its environment. It acts as barrier against cold, heat, injuries, infections, chemicals, radiations or other exogeneous factors, it also known mirror of soul. The skin involved in temperature regulation by storage fat water. an interesting tissue regard to local transdermal application active ingredients for prevention treatment pathological conditions. Topical delivery emerging route drug cosmetic administration. beneficial avoiding side effects rapid metabolism. Many pharmaceutical, technological innovations have been described patented recently field. In this review, main features morphology physiology are presented being followed description classical novel nanoparticulate dermal formulations. biophysical aspects penetration drugs cosmetics into across their investigation diffusion chambers, skin-on-a-chip devices, high-throughput measuring systems with advanced analytical techniques shown. current knowledge about mathematical modeling future perspectives briefly discussed end, all involving nanoparticulated systems.
Язык: Английский
Процитировано
7
International Immunopharmacology, Год журнала: 2024, Номер 141, С. 112658 - 112658
Опубликована: Авг. 12, 2024
Язык: Английский
Процитировано
6