The role of N-acetylcysteine in decreasing neutrophil-lymphocyte ratio in COVID-19 patients: A double-blind, randomized controlled trial. DOI
Nurhasan Agung Prabowo,

Marcelino A. Megantara,

Hendrastutik Apriningsih

и другие.

PubMed, Год журнала: 2023, Номер 3(2), С. e121 - e121

Опубликована: Авг. 1, 2023

N-acetylcysteine has antioxidant and anti-inflammatory activities that could potentially improve the clinical outcomes of coronavirus disease 2019 (COVID-19) patients. inhibits NLRP3 (NOD-, LRR- pyrin domain-containing protein 3) inflammasome results in control oxidative stress cytokine release COVID-19 The aim this study was to assess effect reducing neutrophil-lymphocyte ratio (NLR) A randomized controlled trial conducted among severe moderate treatment group received oral 1200 mg daily (three times a day) standard care for COVID-19, while placebo. NLR determined on first day admission after seventh treatment. paired Student t-test used compare before independent between groups. total 40 were enrolled, 20 people each group, with mean age 44.68±13.24 years old. 9.44 8.84 group. After day, 4.27 11.54 respectively. changes (the pre-treatment compared post-treatment) reduced 4.05 increased 3.34, significantly decreased (

Язык: Английский

Clinical efficacy of N-acetylcysteine for COVID-19: A systematic review and meta-analysis of randomized controlled trials DOI Creative Commons
Tinghui Liu, Jheng‐Yan Wu, Po‐Yu Huang

и другие.

Heliyon, Год журнала: 2024, Номер 10(3), С. e25179 - e25179

Опубликована: Янв. 26, 2024

The association between N-acetylcysteine (NAC) and COVID-19 remains undetermined; therefore, this meta-analysis assessed the clinical efficacy of NAC in treatment patients with COVID-19.

Язык: Английский

Процитировано

2

Impact of N-Acetylcysteine in the mortality of patients hospitalized with COVID-19: a retrospective cohort study DOI

M.A. Galindo-Andúgar,

Ángel Arias, José Alfonso García Guerra

и другие.

Revista Clínica Española (English Edition), Год журнала: 2023, Номер 223(8), С. 479 - 485

Опубликована: Июль 21, 2023

Язык: Английский

Процитировано

2

Efecto de la N-acetilcisteína en la mortalidad de pacientes ingresados por COVID-19: estudio de cohorte retrospectivo DOI

M.A. Galindo-Andúgar,

Ángel Arias, José Alfonso García Guerra

и другие.

Revista Clínica Española, Год журнала: 2023, Номер 223(8), С. 479 - 485

Опубликована: Авг. 7, 2023

Процитировано

2

Covid-19 Clinical Outcomes and N-Acetylcysteine (Covinac Study): A Grade Compliant Meta-Analysis of Randomized Controlled Trials, Molecular Docking, and Dynamics Simulations with Mpro of Sars-Cov-2 DOI
Seshadri Reddy Varikasuvu, Subodh Kumar, Manne Munikumar

и другие.

Опубликована: Янв. 1, 2024

Download This Paper Open PDF in Browser Add to My Library Share: Permalink Using these links will ensure access this page indefinitely Copy URL DOI

Язык: Английский

Процитировано

0

Evaluation of the efficacy of N-acetylcysteine and bromhexine compared with standard care in preventing hospitalization of outpatients with COVID-19: a double blind randomized clinical trial DOI

Arash Eslami Ghayour,

Sasan Nazari,

Fariba Keramat

и другие.

Revista Clínica Española (English Edition), Год журнала: 2024, Номер 224(2), С. 86 - 95

Опубликована: Янв. 11, 2024

Язык: Английский

Процитировано

0

Evaluación de la eficacia de la N-acetilcisteína y la bromhexina en comparación con la atención estándar en la prevención de la hospitalización de pacientes ambulatorios con COVID-19: un ensayo clínico aleatorizado doble ciego DOI
Anahita Eslami-Ghayour,

Sasan Nazari,

Fariba Keramat

и другие.

Revista Clínica Española, Год журнала: 2024, Номер 224(2), С. 86 - 95

Опубликована: Янв. 29, 2024

Процитировано

0

The role of N-acetylcysteine in decreasing neutrophil-lymphocyte ratio in COVID-19 patients: A double-blind, randomized controlled trial. DOI
Nurhasan Agung Prabowo,

Marcelino A. Megantara,

Hendrastutik Apriningsih

и другие.

PubMed, Год журнала: 2023, Номер 3(2), С. e121 - e121

Опубликована: Авг. 1, 2023

N-acetylcysteine has antioxidant and anti-inflammatory activities that could potentially improve the clinical outcomes of coronavirus disease 2019 (COVID-19) patients. inhibits NLRP3 (NOD-, LRR- pyrin domain-containing protein 3) inflammasome results in control oxidative stress cytokine release COVID-19 The aim this study was to assess effect reducing neutrophil-lymphocyte ratio (NLR) A randomized controlled trial conducted among severe moderate treatment group received oral 1200 mg daily (three times a day) standard care for COVID-19, while placebo. NLR determined on first day admission after seventh treatment. paired Student t-test used compare before independent between groups. total 40 were enrolled, 20 people each group, with mean age 44.68±13.24 years old. 9.44 8.84 group. After day, 4.27 11.54 respectively. changes (the pre-treatment compared post-treatment) reduced 4.05 increased 3.34, significantly decreased (

Язык: Английский

Процитировано

1