Biocontrol Science and Technology,
Год журнала:
2023,
Номер
34(1), С. 96 - 110
Опубликована: Дек. 26, 2023
This
study
explored
the
initial
step
to
develop
of
a
potential
biopesticide
for
controlling
Nacobbus
aberrans
(J2)
using
spores
nematophagous
fungus
Arthrobotrys
oligospora
(Ao)
mixed
with
sterile
sheep
faeces.
One
strain
Ao
(50–80)
National
Centre
Disciplinary
Research
in
Animal
Health
and
Innocuity
(INIFAP)
collection
was
used.
The
assay
performed
plastic
glasses.
Three
experimental
groups
were
established
as
follows:
(1)
negative
Control
(only
N.
J2)
(without
fungi);
(2)
positive
control
(pesticide),
5
mL
(0.131
g)
Cabofuran
(®Furadan
350
L)
per
glass;
(3)
Ao,
300,000
total
amount.
Treatment
reduced
population
by
94.7%,
whereas
pesticide,
94.5%
relation
group
(P
≤
0.05).
A
mixture
faeces
containing
reduces
aberrans,
pathogenic
nematode
affecting
health
production
economically
important
crops.
Frontiers in Public Health,
Год журнала:
2023,
Номер
11
Опубликована: Окт. 10, 2023
The
deleterious
effects
of
chemical
or
non-chemical
endocrine
disruptors
(EDs)
on
male
fertility
potential
is
well
documented
but
still
not
fully
elucidated.
For
example,
the
detection
industrial
chemicals'
metabolites
in
seminal
plasma
and
follicular
fluid
can
affect
efficiency
gametogenesis,
maturation
competency
gametes
has
guided
scientists
to
hypothesize
that
disrupting
chemicals
(EDCs)
may
disrupt
hormonal
homoeostasis
by
leading
a
wide
range
control
impairments.
EDCs
exposure
reproductive
health
are
highly
dependent
factors
including
type
EDCs,
duration
exposure,
individual
susceptibility,
presence
other
co-factors.
Research
continue
study
these
complex
interactions.
aim
this
review
summarize
literature
better
understand
risks
France.
Metabolites,
Год журнала:
2024,
Номер
14(3), С. 155 - 155
Опубликована: Март 7, 2024
A
vast
range
of
pesticides
have
been
routinely
employed
for
plant
protection
throughout
the
last
few
decades.
Pesticides
can
enter
non-target
organisms
in
various
ways,
posing
health
hazards.
Exposure
to
different
environmental
pollutants,
including
pesticides,
affect
human
gut
flora.
Metabolites
generated
from
microbiota
play
an
essential
role
host's
by
regulating
metabolic
homeostasis.
disruption
this
equilibrium
lead
emergence
numerous
illnesses
and
their
etiology.
shown
a
recent
studies
harm
microbiome.
As
result,
there
is
urgent
need
investigate
impact
on
microbiota-mediated
immunity.
Metabolic
alterations
host
may
give
better
understanding
pesticide-induced
harm.
This
review
highlights
potential
consequences
pesticide
exposure
composition
function,
mainly
focusing
how
it
might
alter
production
secondary
metabolites
with
downstream
implications
health.
Frontiers in Toxicology,
Год журнала:
2024,
Номер
6
Опубликована: Сен. 18, 2024
Glyphosate
is
a
chemical
compound
derived
from
glycine,
marketed
as
broad-spectrum
herbicide,
and
represents
one
of
the
most
widely
used
pesticides
in
world.
For
long
time,
it
was
assumed
that
glyphosate
harmless,
either
due
to
its
selective
enzymatic
acting
method
on
plants,
because
commercial
formulations
were
believed
contain
only
inert
chemicals.
spread
environment,
general
population
daily
exposed
via
different
routes,
including
consumption
both
plant,
non-plant
based
foods.
has
been
detected
high
amounts
workers’
urine,
but
likewise
bodily
fluids,
such
blood
maternal
milk,
also
60%–80%
population,
children.
Considering
massive
presence,
exposure
could
be
considered
health
risk
for
humans.
Indeed,
2015,
IARC
(International
Agency
Research
Cancer)
classified
derivatives
Group
2A,
probable
human
carcinogens.
In
2022,
nevertheless,
EFSA
(European
Food
Safety
Authority)
stated
available
data
did
not
provide
sufficient
evidence
prove
mutagenic/carcinogenic
effects
glyphosate.
Therefore,
European
Commission
(EC)
decided
renew
approval
another
10
years.
The
purpose
this
review
examine
scientific
literature,
focusing
potential
risks
arising
glyphosate,
metabolites
products
(e.g.,
Roundup
®
),
with
particular
regard
mutagenic
carcinogenic
endocrine
disrupter
(ED)
especially
reproductive
system.
Journal of Food Biochemistry,
Год журнала:
2024,
Номер
2024, С. 1 - 16
Опубликована: Янв. 9, 2024
Coexposure
to
exogenous
neurotoxins,
such
as
fluoride
(F−)
and
dimethoate
(DM),
is
a
serious
public
health
concern.
In
the
current
study,
Wistar
rats
were
exposed
DM
(1/10th
LD50)
F−
(4.5
ppm)
in
drinking
water
individually
well
combination
continuously
for
28
days
effectiveness
of
ginger
quercetin
was
assessed
combating
oxidative
stress-mediated
combined
toxic
effects
on
blood
brain.
Significant
(
)
reductions
observed
levels
total
antioxidant
status
(TAS),
glutathione
peroxidase
(GPx),
(GSH),
activities
catalase
(CAT),
thiols
(TTH),
superoxide
dismutase
(SOD),
aryl
esterase
(AE),
acetylcholinesterase
(AChE)
whereas
significant
elevations
id="M2">p<0.05
malondialdehyde
(MDA)
advanced
oxidation
protein
products
(AOPP)
recorded
brain
coexposed
rats.
Administration
significantly
id="M3">p<0.05
ameliorated
F-
DM-induced
hematotoxicity
neurotoxicity
indicated
by
markers
injury
rats,
which
showed
id="M4">p<0.05
improvement.
Moreover,
pathological
changes,
neurodegeneration,
perivascular
edema,
gliosis,
after
toxicity
(cerebrum
cerebellum)
markedly
reduced
supplementation.
Frontiers in Public Health,
Год журнала:
2024,
Номер
12
Опубликована: Дек. 12, 2024
Over
the
last
decades,
human
infertility
has
become
a
major
concern
in
public
health,
with
severe
societal
and
health
consequences.
Growing
evidence
shows
that
endocrine
disruptors
chemicals
(EDCs)
have
been
considered
as
risk
factors
of
infertility.
Their
presence
our
everyday
life
ubiquitous
because
their
universal
use
food
beverage
containers,
personal
care
products,
cosmetics,
phytosanitary
products.
Exposure
to
these
products
an
impact
on
reproductive
health.
Recent
studies
suggest
women
are
more
exposed
EDCs
than
men
due
higher
chemical
use.
The
aim
this
review
is
understand
possible
link
between
disorders
such
phthalates,
bisphenol,
dioxins,
pesticides.
In
women,
loss
balance
leads
altered
oocyte
maturation,
competency,
anovulation
uterine
disorders,
endometriosis,
premature
ovarian
insufficiency
(POI)
or
embryonic
defect
decreases
Comprehensive Reviews in Food Science and Food Safety,
Год журнала:
2024,
Номер
23(5)
Опубликована: Авг. 8, 2024
Abstract
The
use
of
pesticides
in
viticulture
may
play
a
crucial
role
ensuring
the
health
and
quality
grapes.
This
review
analyzes
most
common
used,
illustrating
their
classification
toxicity,
variations
throughout
winemaking
process.
Fungicides
are
generally
harmless
or
mildly
toxic,
whereas
insecticides
classified
as
either
highly
moderately
hazardous.
Potential
alternatives
to
synthetic
wine
production
also
reviewed,
thereby
including
biopesticides
biological
agents.
Analytical
methods
for
detecting
quantifying
pesticide
residues
then
described,
liquid
chromatography
gas
coupled
with
mass
spectrometry.
discusses
impact
process
on
content.
Pesticides
strong
hydrophobicity
were
more
likely
accumulate
solid
byproducts,
hydrophilic
distributed
phase.
Grape's
skin
contains
lipids,
so
hydrophobic
adsorb
strongly
grape
surfaces
clarification
has
been
shown
be
effective
reduction
compounds.
Therefore,
final
could
have
quantities
pesticides.
Alcoholic
fermentation
dissipation.
However,
an
antagonistic
effect
yeasts,
affecting
safety
products.
proteomic
genomic
analyses
yeast
growth
reviewed
understand
effects
during
fermentation.
last
section
describes
new
used
removing
from
grapes
wine,
improving
product
reducing
harmful
effects.
npj Biofilms and Microbiomes,
Год журнала:
2025,
Номер
11(1)
Опубликована: Апрель 25, 2025
We
tested
the
hypothesis
that
e-cigarette
aerosol
is
metabolized
by
indigenous
oral
microbiome,
leading
to
structural
and
functional
alterations.
combined
untargeted
metabolomics
of
in
vitro
commensal-rich
pathogen-rich
biofilms
with
metatranscriptomics
fluorescent
microscopy
verified
results
human
samples.
Spectral
deconvolution
4215
peaks
identified
969
exposomal
endogenous
metabolites
mapped
23
metabolic
pathways.
The
clustered
both
characteristics
biofilm
composition;
several
were
saliva
vapers.
E-cigarette
exposure
upregulated
xenobiotic
degradation,
capsule,
peptidoglycan
biosynthesis,
organic
carbon-compound
metabolism,
antimicrobial
resistance,
secretion
systems.
also
altered
architecture
characterized
low
surface-area
biovolume
ratio,
high
biomass,
diffusion
distance.
In
conclusion,
our
data
suggest
bacterial
metabolism
triggers
a
quorum-sensing-regulated
stress
response
which
mediates
formation
dense,
exopolysaccharide-rich
health-compatible
communities
antibiotic
resistance
virulence
amplification
disease-associated
communities.
Journal of Xenobiotics,
Год журнала:
2025,
Номер
15(3), С. 83 - 83
Опубликована: Июнь 1, 2025
Pesticides
play
an
essential
role
in
modern
agriculture,
yet
increasing
evidence
links
their
widespread
use
to
neurotoxic
effects
that
contribute
both
neurodegenerative
and
neurodevelopmental
disorders.
In
recent
years,
new
classes
of
pesticides
such
as
neonicotinoids
pyrethroids
have
garnered
attention
due
potential
disrupt
neurodevelopment,
even
at
low
exposure
levels.
Furthermore,
emerging
underscores
the
involvement
gut–brain
axis,
neuroinflammation,
epigenetic
modulation
pesticide-induced
neuropathology.
This
review
aims
synthesize
these
latest
advancements
while
highlighting
underexplored
mechanisms,
thereby
offering
a
comprehensive
current
perspective
on
pesticide-related
neurotoxicity.
Data
from
Rapid
Alert
System
for
Food
Feed
(RASFF)
indicate
several
food
products
include
residues
recognized
properties.
Although
environmental
levels
are
lower
than
those
occupational
contexts,
magnitude
persistence
food-based
demand
thorough
evaluation.
integrates
coming
epidemiological,
vivo
vitro
investigations,
emphasizing
correlations
between
pesticide
conditions
Alzheimer’s
disease,
Parkinson’s
cognitive
deficits
children.
Neurodevelopmental
toxicity
is
especially
alarming
since
symptoms
may
manifest
subtly
with
delayed
onset
after
early-life
exposure,
indicating
significant
need
careful
evaluation
safety
assessments.
Improved
regulatory
procedures
public
health
efforts
reducing
long-term
brain
damage.
