Generation of T cell hybridoma as a technique for study the immune response against bacterial infections DOI Creative Commons

Jamila Alhoderi

Journal of Pure & Applied Sciences, Год журнала: 2023, Номер 22(3), С. 185 - 190

Опубликована: Окт. 2, 2023

Study of the acquired immune responses against microbial infection has a high importance, as it is fundamental basis designing vaccines microbes and production specific antibodies infections. Different methods have been established to study infections using different types cells. The main cells system are T which generate cellular response B that produce humoral response. One techniques can be generated, continues cell called hybridoma. This used system. It generated from lines immunity, hybridoma, or Generation hybridoma ( fusion between antigen-specific primary with an immortal thymoma line) significant technique demonstrate mechanisms antigen presenting In addition, basic for monoclonal antibody based on i.e., hybridoma). article aims present procedure generating its application M5 protein Streptococcus pyogenes group A - GAS ) practical example. important issue highlight such successful technique.

Язык: Английский

A Review of Advances in Molecular Imaging of Rheumatoid Arthritis: From In Vitro to Clinic Applications Using Radiolabeled Targeting Vectors with Technetium-99m DOI Creative Commons
Muhammad Ali, Viviana Benfante, Domenico Di Raimondo

и другие.

Life, Год журнала: 2024, Номер 14(6), С. 751 - 751

Опубликована: Июнь 12, 2024

Rheumatoid arthritis (RA) is a systemic autoimmune disorder caused by inflammation of cartilaginous diarthrodial joints that destroys and cartilage, resulting in synovitis pannus formation. Timely detection effective management RA are pivotal for mitigating inflammatory consequences, potentially influencing disease progression. Nuclear medicine using radiolabeled targeted vectors presents promising avenue diagnosis response to treatment assessment. Radiopharmaceutical such as technetium-99m (

Язык: Английский

Процитировано

3
Milk-derived small extracellular vesicles inhibit the MAPK signaling pathway through CD36 in chronic apical periodontitis DOI Creative Commons
Meng Xia,

Jiayin Ding,

Saixuan Wu

и другие.

International Journal of Biological Macromolecules, Год журнала: 2024, Номер 274, С. 133422 - 133422

Опубликована: Июнь 24, 2024

Small extracellular vesicles derived from milk (Milk-sEVs) have the advantages of easy availability, low cost, toxicity, and inhibition inflammation. CD36 mediates inflammation stress in a variety disease states. The purpose this study was to investigate role Milk-sEVs inhibiting fibroblast through provide reference data for treatment chronic apical periodontitis.

Язык: Английский

Процитировано

2
Generation of T cell hybridoma as a technique for study the immune response against bacterial infections DOI Creative Commons

Jamila Alhoderi

Journal of Pure & Applied Sciences, Год журнала: 2023, Номер 22(3), С. 185 - 190

Опубликована: Окт. 2, 2023

Study of the acquired immune responses against microbial infection has a high importance, as it is fundamental basis designing vaccines microbes and production specific antibodies infections. Different methods have been established to study infections using different types cells. The main cells system are T which generate cellular response B that produce humoral response. One techniques can be generated, continues cell called hybridoma. This used system. It generated from lines immunity, hybridoma, or Generation hybridoma ( fusion between antigen-specific primary with an immortal thymoma line) significant technique demonstrate mechanisms antigen presenting In addition, basic for monoclonal antibody based on i.e., hybridoma). article aims present procedure generating its application M5 protein Streptococcus pyogenes group A - GAS ) practical example. important issue highlight such successful technique.

Язык: Английский

Процитировано

0