Non-targeted metabolomics-mediated elucidation of metabolite changes in Polygonatum kingianum during traditional steaming with black beans DOI Creative Commons

Haiyan Zhu,

Zhikun Pei, Lei Zhang

и другие.

Frontiers in Nutrition, Год журнала: 2025, Номер 12

Опубликована: Апрель 11, 2025

Polygonatum is a traditional medicinal and edible plant often prepared by steaming it with ingredients like yellow rice wine black beans. However, the metabolic changes in kingianum (PK) during method beans have not been previously reported. This study aims to explore how addition of degree affect quality PK. quantified polysaccharides, reducing sugars, saponins, flavonoids PK subjected varied cycles, while also integrating color measurement, sensory evaluation, non-targeted metabolomics analysis. rich lipids, amino acids, flavonoids, organic acids. Notably, we observed production significant accumulation daidzein daidzin (two primary active compounds derived from beans) as well triterpenoid saponins (including Sandosaponin A, Soyasaponin II-III, V, Pisumsaponin I-II) steamed (p < 0.05). After three multiple bioactive levels peaked or stabilized, which was consistent (score: 94/100). Compared raw PK, P3 stage exhibited increases total 21.29, 35.02, 49.13, 44.76%, respectively 0.05), sugars showed remarkable increase 160.94-fold 0.01), polysaccharides decreased significantly 43.33% 0.01). provides first evidence that can synergistically diversity isoflavones optimal achieved after rounds steaming. These findings validate scientific efficacy processing method. Our results advocate for continued use bean enhance nutritional health-promoting value providing template innovation herbal techniques based on auxiliary ingredients.

Язык: Английский

The role of fermentation with lactic acid bacteria in quality and health effects of plant‐based dairy analogues DOI Creative Commons
Erenay Erem, Meral Kılıç‐Akyılmaz

Comprehensive Reviews in Food Science and Food Safety, Год журнала: 2024, Номер 23(4)

Опубликована: Июль 1, 2024

Abstract The modern food industry is undergoing a rapid change with the trend of production plant‐based products that are more sustainable and have less impact on nature. Plant‐based dairy analogues been increasingly popular due to their suitability for individuals milk protein allergy or lactose intolerance those preferring diet. Nevertheless, still insufficient nutritional quality, undesirable structure, earthy, green, bean‐like flavor compared products. In addition, most foods contain lesser amounts essential nutrients, antinutrients limiting bioavailability some allergenic proteins. Novel processing technologies can be applied homogeneous stable structure. On other hand, fermentation matrix lactic acid bacteria provide solution these problems. Additional nutrients produced degraded by bacterial metabolism, thereby increasing value. Allergenic proteins hydrolyzed reducing immunoreactivity. has found reduce undesired flavors enhance various bioactivities plant foods. However, main challenge in fermented mimic familiar dairy‐like producing major compounds than organic acids, yielding profile similar Further studies required improvement through selection special microbial cultures formulations.

Язык: Английский

Процитировано

4

Natural Saponins on Cholesterol‐Related Diseases: Treatment and Mechanism DOI Open Access

Man‐Yu Xiao,

Si Li, Wenjing Pei

и другие.

Phytotherapy Research, Год журнала: 2025, Номер unknown

Опубликована: Янв. 4, 2025

ABSTRACT Saponins are compounds composed of lipophilic aglycones linked to hydrophilic sugars. Natural saponins isolated from plants and some Marine organisms. As important cholesterol‐lowering drugs, natural have attracted wide attention for their therapeutic potential in a variety cholesterol‐related metabolic diseases. To review the effects on diseases, deepen understanding mechanism saponins. The literature related diseases was collected using keywords “saponins” “cholesterol” PubMed, Web Science, Google Scholar January 2000 May 2024. total number articles 240 after excluding irrelevant articles. can regulate cholesterol prevent treat such as atherosclerosis, diabetes, liver disease, hyperlipidemia, cancer, obesity. Mechanistically, synthesis uptake through AMPK/SREBP2/3‐hydroxy‐3‐methyl‐glutaryl coenzyme A reductase pathway PCSK9/LDLR pathway, efflux esterification targeting Liver X receptor/ABC ACAT family. broad application prospects regulating metabolism, development more drugs provides new train thought. However, it is still necessary further explore molecular expand clinical trials provide evidence.

Язык: Английский

Процитировано

0

Harnessing Natural Saponins: Advancements in Mitochondrial Dysfunction and Therapeutic Applications DOI

Hongmei Liu,

Huan Wang, Xinyu Lin

и другие.

Phytomedicine, Год журнала: 2025, Номер 138, С. 156383 - 156383

Опубликована: Янв. 10, 2025

Язык: Английский

Процитировано

0

Functional foods and aging and antiaging: a recipe for longevity DOI
Sarra Akermi,

Ashwani Sharma,

Abira Dey

и другие.

Elsevier eBooks, Год журнала: 2025, Номер unknown, С. 161 - 173

Опубликована: Янв. 1, 2025

Язык: Английский

Процитировано

0

Molecular detection of mecA gene from methicillin-resistant Staphylococcus aureus isolated from clinical and environmental samples and its potential inhibition by phytochemicals using in vitro and in silico approach DOI Creative Commons
Mohammed Mustapha Mohammed, Mustafa Alhaji Isa, Mustapha Abubakar

и другие.

In Silico Pharmacology, Год журнала: 2025, Номер 13(1)

Опубликована: Фев. 10, 2025

Язык: Английский

Процитировано

0

Effects of High Hydrostatic Pressure (HHP) on the Extraction and Functional Characteristics of Chickpea Proteins and Saponins DOI
Elif Gökçen Ateş, Gokcem Tonyali Karsli, Hami Alpas

и другие.

ACS Food Science & Technology, Год журнала: 2025, Номер unknown

Опубликована: Фев. 15, 2025

This study investigated the influence of High Hydrostatic Pressure (HHP) on extraction proteins and saponins from chickpeas, as well its effects their functional properties. HHP was applied at two pressure levels (200 400 MPa) 40 °C for 5 min compared with conventional heating (90 min, no pressure). The results showed that significantly improved soluble saponins, especially 200 MPa. At higher (400 MPa), there a slight decrease in due to possible formation protein aggregates. also found HHP-treated samples had better foaming emulsifying abilities, which are important food applications. Emulsions produced under were more stable than those control treatment. Overall, proved be an effective method improving both functionality chickpea bioactives, potential applications food.

Язык: Английский

Процитировано

0

Green Approach for the Purification of the Bioactive Compound Saponin from the Root Extract of Argemone mexicana and the Evaluation of Antioxidant, Antimicrobial, Anti-inflammatory and Anticancer Activities DOI

Enayathulla Kathar Basha,

Vijaya Dhamodaran

Deleted Journal, Год журнала: 2025, Номер unknown

Опубликована: Фев. 24, 2025

Язык: Английский

Процитировано

0

Development and Optimisation of a red ginseng Beverage from Codonopsis javanica in Vietnam: Sensory and Microbial Safety Evaluation DOI Creative Commons

T T Ho,

The Linh Pham, H. T. Nguyen

и другие.

Natural Product Communications, Год журнала: 2025, Номер 20(2)

Опубликована: Фев. 1, 2025

Objectives The study aimed to develop a protocol for producing beverage from Codonopsis javanica ( C. javanica) (red ginseng) root extract, incorporating additives enhance its overall sensory appeal. Key parameters, including triterpenoid saponin content, °Brix, pH, suspended solids, and moisture, were analyzed. Sensory evaluations conducted optimize the formulation, microbial safety of final product was assessed. Methods Dried roots ground into powder extracted using enzyme-assisted extraction with viscozyme ® L. extract analyzed °Brix measured moisture content. Optimal heating conditions solid content determined at three temperatures (70 °C, 75 °C 80 °C) 8 12 min, respectively. Different ratios red ginseng water (7:3, 8:2, 9:1 10:0), as well varying concentrations citric acid (0.0% 0.1%), sucrose (8%, 10%, 12% 14%), honey (1% 1.5%), surveyed evaluation by panel testers. Product pasteurization (at 100 15 min) performed ensure microbiological standards assessed after 28 days storage. Results optimal method yielded high (9.20), low pH (3.62), 53.66 mg/100 g. Heating min resulted in most favourable results achieved dilution ratio 8:2 (ginseng extract:water). addition alone or combined 1.5% provided best taste scores. Pasteurization ensured absence microorganisms, meeting national non-alcoholic beverages. Conclusion successfully developed qualities safety. findings provide foundation further commercialization beverages, highlighting importance balanced formulations proper processing techniques.

Язык: Английский

Процитировано

0

Phytochemical compounds, vitamin C levels, and antioxidant activity of soursop leaves (Annona muricata Linn) tea powder under various drying durations. DOI Creative Commons
Siti Ika Fitrasyah,

Sari Ningsih,

Nurdin Rahman

и другие.

Nutrición clínica y dietética hospitalaria/Nutrición clínica, dietética hospitalaria, Год журнала: 2025, Номер 45(1)

Опубликована: Март 3, 2025

Introduction: Soursop leaves (Annona muricata Linn) possess numerous properties that play a significant role in preventing various diseases, such as antibacterial, antioxidant, anticancer, anti-inflammatory activities, and their ability to act immunomodulators. Degenerative diseases are primarily caused by the harmful effects of free radicals. Oxidative stress induced radicals leads degenerative can damage body. Antioxidants mitigate this donating electrons radicals, thereby playing crucial body’s defense mechanisms. Aim: This study aims analyze phytochemical compounds, vitamin C levels, antioxidant activity soursop leaf tea powder under varying drying durations. Methods: quantitative research employed descriptive design based on laboratory testing. Phytochemical compounds were analyzed qualitatively, levels measured using titration method, was determined Ultra Violet-Visible (UV-Vis) Spectrophotometry with 2,2-diphenyl-1-picrylhydrazyl (DPPH) method. A one-way Analysis Variance (ANOVA) used for statistical analysis, data obtained followed normal distribution. Results: The results revealed all samples tested positive including flavonoids, saponins, tannins, alkaloids, terpenoids. effect duration variations observed, p-value < 0.05. Conclusion: In conclusion, promising source natural bioactive at 50°C 3 6 hours effectively preserving content enhancing activity. However, extending time 12 may lead slight reduction these beneficial properties. Statistical analyses confirm significantly affects both powder.

Язык: Английский

Процитировано

0

Current Insights on the Effects of Medicinal Plants in the Management of Obesity and Infectious Diseases: An Update from 2020. DOI Creative Commons

Ofoezie Ezichi Favour,

Ogbonna Chinwendu Angela,

George Tiffany Ezinne

и другие.

Aspects of Molecular Medicine, Год журнала: 2025, Номер unknown, С. 100075 - 100075

Опубликована: Март 1, 2025

Язык: Английский

Процитировано

0