Pathogenic and therapeutic roles of extracellular vesicles in sepsis DOI Creative Commons
Benshuai You, Yang Yang, Wei Jing

и другие.

Frontiers in Immunology, Год журнала: 2025, Номер 16

Опубликована: Фев. 4, 2025

Sepsis is a systemic injury resulting in vascular dysfunction, which can lead to multiple organ even shock and death. Extracellular vesicles (EVs) released by mammalian cells bacteria have been shown play important roles intercellular communication progression of various diseases. In past decades, the functional role EVs sepsis its complications has well explored. are one paracrine components cells. By delivering bioactive materials, promote immune responses, particularly development inflammation. addition, serve as beneficial tools for therapeutic cargos. this review, we discuss dual treatment sepsis, exploring their intricate involvement both inflammation tissue repair processes. Specifically, remarkable engineered strategies based on highlighted. The engineering EVs-mediated drug delivery release offer broad prospects effective sepsis. EVs-based approaches provide novel avenue diagnosing opportunities more precise intervention.

Язык: Английский

Pathogenic and therapeutic roles of extracellular vesicles in sepsis DOI Creative Commons
Benshuai You, Yang Yang, Wei Jing

и другие.

Frontiers in Immunology, Год журнала: 2025, Номер 16

Опубликована: Фев. 4, 2025

Sepsis is a systemic injury resulting in vascular dysfunction, which can lead to multiple organ even shock and death. Extracellular vesicles (EVs) released by mammalian cells bacteria have been shown play important roles intercellular communication progression of various diseases. In past decades, the functional role EVs sepsis its complications has well explored. are one paracrine components cells. By delivering bioactive materials, promote immune responses, particularly development inflammation. addition, serve as beneficial tools for therapeutic cargos. this review, we discuss dual treatment sepsis, exploring their intricate involvement both inflammation tissue repair processes. Specifically, remarkable engineered strategies based on highlighted. The engineering EVs-mediated drug delivery release offer broad prospects effective sepsis. EVs-based approaches provide novel avenue diagnosing opportunities more precise intervention.

Язык: Английский

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