The gut-eye axis: the retinal/ocular degenerative diseases and the emergent therapeutic strategies DOI Creative Commons

Sonda Kammoun,

Mona Rekik,

Aryj Dlensi

и другие.

Frontiers in Cellular Neuroscience, Год журнала: 2024, Номер 18

Опубликована: Сен. 26, 2024

The interplay between human microbiota and various physiological systems has garnered significant attention in recent years. gut plays a critical role maintaining homeostasis influences aspects of health, particularly via the brain axis. Since 2017, challenging concept gut-retina axis emerged thanks to network analysis emphasizing potential disruption development age-related macular degeneration further retinal damages. Many other ocular disorders have been linked dysbiosis microbiota, including uveitis glaucoma. It shown that age related can be prevented or reversed using diet induces changes microbiota. link as well others types such surface development/progression inherited degenerations degenerative eye diseases, recently broadened. Therefore, pathogenesis several diseases associated with larger perception called This mini-review examines mechanisms underlying suggests implications for management diseases. By understanding modulation its impact on disease, this provides insight into therapeutic interventions avenues future research.

Язык: Английский

The gut-eye axis: the retinal/ocular degenerative diseases and the emergent therapeutic strategies DOI Creative Commons

Sonda Kammoun,

Mona Rekik,

Aryj Dlensi

и другие.

Frontiers in Cellular Neuroscience, Год журнала: 2024, Номер 18

Опубликована: Сен. 26, 2024

The interplay between human microbiota and various physiological systems has garnered significant attention in recent years. gut plays a critical role maintaining homeostasis influences aspects of health, particularly via the brain axis. Since 2017, challenging concept gut-retina axis emerged thanks to network analysis emphasizing potential disruption development age-related macular degeneration further retinal damages. Many other ocular disorders have been linked dysbiosis microbiota, including uveitis glaucoma. It shown that age related can be prevented or reversed using diet induces changes microbiota. link as well others types such surface development/progression inherited degenerations degenerative eye diseases, recently broadened. Therefore, pathogenesis several diseases associated with larger perception called This mini-review examines mechanisms underlying suggests implications for management diseases. By understanding modulation its impact on disease, this provides insight into therapeutic interventions avenues future research.

Язык: Английский

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