Oral Health Status and Factors Associated with Oral Health in Patients with Alzheimer’s Disease: A Matched Case-Control Observational Study

Journal of Clinical Medicine, Год журнала: 2025, Номер 14(5), С. 1412 - 1412

Опубликована: Фев. 20, 2025

Background: Alzheimer’s disease (AD) is a chronic neurodegenerative disease, ranking as the seventh leading cause of death in both sexes. There increasing awareness role periodontal and severe tooth loss modifiable risk factor for developing AD. The aim present observational study was to assess AD patients with non-affected healthy controls context their dental health outcomes; additionally, potential impact anamnestic factors lifestyle habits on oral outcomes also studied. Methods: A total n = 41 receiving treatment at Department Psychiatry, University Szeged, were compared age- gender-matched from individuals seeking retirement homes (mean age 83.32 ± 7.82 years). Dental status indices assessed according World Health Organization (WHO) criteria. Results: Overall, 51.2%, 68.3%, 87.8% received mood stabilizers, drugs non-cognitive symptoms cognitive symptoms, respectively. Severe observed 43.9% 56.1% controls, no significant differences among regarding studied (p > 0.05 all indicators). had significantly higher plaque (%) (59.06 15.45 vs. 41.35 7.97; p < 0.001), bleeding probing (BOP%) (62.65 12.00 40.12 10.86; pocket depth [PD] (2.63 0.56 2.29 0.13; 0.002) attachment [AL] (2.85 0.79 2.39 0.41; 0.026) values, controls. Smoking (vs. non-smokers; 56.28 12.36 51.40 13.23, 0.038) consumption alcohol non-drinkers; 58.68 9.86 54.78 14.86, 0.040) associated [%], while similar effects shown parameters 0.05). In contrast, coffee intake vitamin supplement use effect or cases). Conclusions: results our underscore substantial needs patients, calling heightened healthcare professionals.

Язык: Английский

Special Issue “Molecular Insights into the Role of Exercise in Disease and Health”

International Journal of Molecular Sciences, Год журнала: 2025, Номер 26(7), С. 2954 - 2954

Опубликована: Март 25, 2025

Regular physical activity is a fundamental determinant of overall health and key factor in mitigating the risk numerous pathological conditions [...].

Язык: Английский