Evaluating the Link Between Cardiovascular Risk and Alzheimer’s Disease: A Comprehensive Case-Control Study in Castilla y León, Spain

Applied Sciences, Год журнала: 2025, Номер 15(6), С. 3409 - 3409

Опубликована: Март 20, 2025

Alzheimer’s disease (AD) represents a growing public health challenge due to its increasing prevalence, projected reach 150 million cases by 2050. Characterised neuropathological changes such as the accumulation of beta-amyloid peptide and hyperphosphorylated Tau protein, is related genetic environmental factors. The main objective this research has been analyse possible relationship between some cardiovascular factors AD. This analytical observational case-control study carried out in Castilla y León (Spain), comprised total 511 individuals 60 90 years age, whom 260 had diagnosis AD rest were healthy individuals. results showed that group with predominantly women, widowed primary education, who higher prevalence family history disease. It was also observed hypertension, cardiac pathology diabetes mellitus three risk significant increased differences patients compared control Although precise mechanisms require further research, these underline importance addressing complex interactions prevention

Язык: Английский

PCSK9 in Vascular Aging and Age-Related Diseases

Aging and Disease, Год журнала: 2025, Номер unknown, С. 0 - 0

Опубликована: Янв. 1, 2025

Язык: Английский