Gels, Год журнала: 2025, Номер 11(3), С. 198 - 198

Опубликована: Март 12, 2025

Polysaccharide-based hydrogels have emerged as indispensable materials in tissue engineering and wound healing, offering a unique combination of biocompatibility, biodegradability, structural versatility. Indeed, their three-dimensional polymeric network high water content closely resemble the natural extracellular matrix, creating microenvironment for cell growth, differentiation, regeneration. Moreover, intrinsic tunable chemical structure, non-toxicity, minimal immunogenicity make them optimal candidates prolonged drug delivery systems. Notwithstanding numerous advantages, these polysaccharide-based are confronted with setbacks such variability material qualities depending on source, susceptibility to microbial contamination, unregulated absorption, inadequate mechanical strength, unpredictable degradation patterns which limit efficacy real-world applications. This review summarizes recent advancements application hydrogels, including cellulose, starch, pectin, zein, dextran, pullulan hyaluronic acid innovative solutions delivery, engineering, regenerative medicine. Future research should concentrate optimizing hydrogel formulations enhance effectiveness medicine antimicrobial therapy.

Язык: Английский