Benefits of Natural Antioxidants on Oral Health
Antioxidants,
Год журнала:
2023,
Номер
12(6), С. 1309 - 1309
Опубликована: Июнь 20, 2023
In
recent
years,
special
attention
has
been
paid
to
the
correlation
between
oxidation–reduction
mechanisms
and
human
health.
The
free
radicals
produced
via
physiological
cellular
biochemical
processes
are
major
contributors
oxidation
phenomena.
Their
instability
is
cause
of
damage.
Free
radical
reactive
oxygen
species
containing
best-known
ones.
body
neutralises
harmful
effects
production
endogenous
antioxidants
(superoxide
dismutase,
catalase,
glutathione,
melatonin).
field
study
nutraucetics
found
antioxidant
capacity
in
substances
such
as
vitamins
A,
B,
C,
E,
coenzyme
Q-10,
selenium,
flavonoids,
lipoic
acid,
carotenoids,
lycopene
contained
some
foods.
There
several
areas
investigation
that
aim
research
interaction
species,
exogenous
antioxidants,
microbiota
promote
increased
protection
peroxidation
macromolecules
(proteins,
lipids)
by
maintaining
a
dynamic
balance
among
make
up
microbiota.
this
scoping
review,
we
map
scientific
literature
on
oxidative
stress
related
oral
microbiota,
use
natural
counteract
it,
assess
volume,
nature,
characteristics,
type
studies
available
date,
suggest
possible
gaps
will
emerge
from
analysis.
Язык: Английский
Salvia deserti Decne., an endemic and rare subshrub from Arabian desert: antidiabetic and antihyperlipidemic effects of leaf hydroethanolic extracts
Frontiers in Pharmacology,
Год журнала:
2025,
Номер
16
Опубликована: Фев. 10, 2025
Introduction
Diabetes
is
a
major
health
issue
that
has
reached
alarming
levels
worldwide.
Although
their
effectiveness,
the
antidiabetic
drugs
have
many
side
effects
such
as
cardiovascular
diseases,
kidney
failure,
and
hepatic
complications.
Many
plant
species
of
genus
Salvia
L.
“Arabian
desert
sage”
(
deserti
)
should
began
to
be
focus
phytochemical
bioactivity
studies.
Methods
The
study
aims
investigate,
first-ever,
antihyperlipidemic
leaf
hydroethanolic
extract
S.
deserti,
an
endemic
rare
subshrub
from
Arabian
desert.
A
single
intraperitoneal
injection
alloxan
monohydrate
(160
mg/kg)
was
used
induce
type-2
diabetes.
Development
diabetes
confirmed
by
measuring
blood
glucose
collected
tail
vein
after
72
h
injection.
Oral
administration
extracts
at
200
400
mg/kg
for
14
days
were
tested
on
alloxan-induced
diabetic
mice
animals
divided
into
6
groups
each.
identity
phenolic
compounds
S
.
conducted
through
HPLC-Electrospray
Ionization-Mass
Spectrometry
(LC-ESI-MS)
analyses.
Results
significantly
decreased
restored
renal
function
reducing
ALT,
AST,
ALP,
GGT,
LDH,
urea
creatinine.
An
improved
lipid
profile
revealed
reduced
TC,
TG
LDL
coupled
with
increased
level
HDL
also
observed.
Moreover,
treatment
relieved
oxidative
stress
(reduction
MDA
H
2
O
activity
antioxidant
enzymes
SOD,
CAT
GPx.
presence
several
(derivatives
ferulic,
coumaric,
caffeic
acids,
among
other
derivatives)
could
least
in
part
explain
obtained
data
empower
use
source
bioactive
ingredients
antioxidant,
properties.
Discussion
Our
research
unveiled
potential
effectively
manage
its
associated
dyslipidemia
improving
status,
recovery
liver
functions
presumably
increasing
insulin
secretion
sensitivity
peripheral
tissues
insulin.
Язык: Английский
Amorphophallus konjac: traditional uses, bioactive potential, and emerging health applications
Frontiers in Plant Science,
Год журнала:
2025,
Номер
16
Опубликована: Фев. 21, 2025
Amorphophallus
konjac
is
a
perennial
plant
native
to
Southeast
Asia,
renowned
for
its
edible
corms
and
rich
nutritional
value.
The
bioactive
component,
glucomannan
(KGM),
has
garnered
significant
attention
due
broad
applications.
This
review
aims
provide
comprehensive
overview
of
the
traditional
uses,
chemical
physical
properties,
modern
health
applications
KGM.
It
highlights
cutting-edge
research,
discusses
challenges
limitations,
identifies
future
directions
advancing
utility
KGM
in
nutrition.
demonstrates
remarkable
benefits,
including
improving
metabolic
through
weight
management,
blood
glucose
stabilization,
lipid
profile
enhancement.
also
plays
vital
role
gut
health.
Emerging
evidence
anti-inflammatory
immune-regulatory
effects,
with
managing
inflammatory
bowel
disease,
hyperthyroidism,
colorectal
cancer
(CRC).
Recent
advancements
multi-omics
analyses
high-throughput
screening
(HTS)
approaches
have
improved
extraction,
characterization,
evaluation.
However,
potential
side
effects
such
as
gastrointestinal
discomfort
allergenicity,
along
maintaining
purity
molecular
consistency,
require
careful
consideration.
versatile
dietary
fiber
extensive
functional
foods,
nutraceuticals,
therapeutic
interventions.
Future
research
should
focus
on
enhancing
KGM's
bioavailability,
developing
targeted
delivery
systems,
formulating
novel
Язык: Английский
A comprehensive study on the underlying mechanisms of the lipid-lowering effects of Bao Li Er Capsule in hyperlipidemia
Xiao Fu,
Jingxian Xing,
Chengjun Yuan
и другие.
Journal of Traditional and Complementary Medicine,
Год журнала:
2025,
Номер
unknown
Опубликована: Март 1, 2025
Язык: Английский
Herbal Products as Complementary or Alternative Medicine for the Management of Hyperglycemia and Dyslipidemia in Patients with Type 2 Diabetes: Current Evidence Based on Findings of Interventional Studies
Journal of Nutrition and Metabolism,
Год журнала:
2024,
Номер
2024(1)
Опубликована: Янв. 1, 2024
Type
2
diabetes
(T2D)
is
known
as
a
major
public
health
problem
with
noticeable
adverse
impact
on
quality
of
life
and
expenditures
worldwide.
Despite
using
routine
multiple
pharmacological
nonpharmacological
interventions,
including
diet
therapy
increasing
physical
activity,
controlling
this
chronic
disease
remains
challenging
issue,
therapeutic
goals
are
often
not
achieved.
Therefore,
recently,
other
procedures,
such
herbal
products
functional
foods
complementary
or
alternative
medicine
(CAM),
have
received
great
attention
new
approach
to
managing
T2D
complications,
according
the
literature.
We
reviewed
existing
evidence
that
supports
various
fundamental
medicinal
herbs,
cinnamon,
saffron,
ginger,
jujube,
turmeric,
barberry,
CAM
adjunctive
strategies
for
patients.
The
current
review
addressed
different
aspects
potential
abovementioned
in
improving
glycemic
indices
lipid
profiles,
effect
size
reported
studies,
their
effective
dose,
possible
side
effects,
herbs‐drug
interactions,
action
mechanisms.
Язык: Английский
An unusual case of type I hyperlipidemia - infant with acute encephalopathy, bulging fontanel, vomiting and pink blood: a case report
BMC Pediatrics,
Год журнала:
2024,
Номер
24(1)
Опубликована: Дек. 19, 2024
Familial
chylomicronemia
syndrome
(FCS)
is
a
rare
genetic
disorder
with
heterogeneous
presentation,
where
acute
encephalopathy
rarely
described
in
literature.
Therefore,
initial
neurologic
symptoms
could
make
the
diagnosis
and
treatment
challenging.
A
four-month-old
male
infant
presented
encephalopathy,
vomiting,
bulging
fontanel,
decreased
appetite
failure
to
thrive.
He
had
extremely
lipemic
serum
anemia.
Intracranial
computed
tomography
(CT)
revealed
lipid
collection
which
was
suspected
be
epidermoid
cyst,
also
deposits
extra-axial
intravascular
location.
This
initially
as
ruptured
intracranial
cyst
dissemination
of
content,
including
dissemination.
Together
clinical
signs
raised
pressure
it
discussed
whether
should
surgically
removed.
Since
blood
sample
appearence
milky
child
rather
stable,
surgery
wasn't
performed
exchange
transfusion
(ET)
started
immediately.
Only
after
ET
possible
obtain
laboratory
results
status
(triglycerides
were
106.8
mmol/l).
At
that
point
we
underlining
cause
disease.
Three
cycles
plasmapheresis
followed
ET,
resolved
almost
completely,
despite
remaining
on
brain
CT
scan
ultrasound,
some
regression.
After
these
repeated
imaging
studies,
concluded
'cyst'
actually
largest
collection.
The
definitive
confirmed
FCS.
short
course
insulin,
antioxidants
fibrates
given,
but
discontinued
confirmation
due
lack
supporting
data
Effective
only
maintenance
diet
consisting
formula
low
fat
high
medium-chain
triglycerides.
On
discharge
infant's
neurological
status,
except
mild
hypotonia,
normal,
he
thriving
well,
good
no
case
FCS
presenting
mimicked
picture
differential
this
case.
Initial
interpretation
studies
didn't
delay
treatment.
With
right
treatment,
disease
reversible
satisfactory
outcome.
Язык: Английский
Estimation of antioxidant and hypolipidemic activities of extracts of Citrus x aurantium leaves in vitro
Loulia Al Hawat,
Loai Alallan
Phytomedicine Plus,
Год журнала:
2024,
Номер
unknown, С. 100723 - 100723
Опубликована: Дек. 1, 2024
Язык: Английский
Inhibitory effect of trans-tiliroside on very low-density lipoprotein secretion in HepG2 cells and mouse liver
Akifumi Nagatomo,
M. Kohno,
Hirosato Kawakami
и другие.
Journal of Natural Medicines,
Год журнала:
2023,
Номер
78(1), С. 180 - 190
Опубликована: Ноя. 16, 2023
Abstract
An
acylated
flavonol
glycoside,
trans
-tiliroside
(
1
),
is
found
in
certain
parts
of
different
herbs,
including
the
seeds
Rosa
canina
(Rosaceae)
.
Previous
studies
on
compound
have
focused
triglyceride
(TG)
metabolism,
its
anti-obesity
and
intracellular
TG
reduction
effects.
In
present
study,
effects
cholesterol
(CHO)
metabolism
were
investigated
using
human
hepatocellular
carcinoma-derived
HepG2
cells
mice.
Compound
decreased
CHO
secretion
cells,
which
was
enhanced
by
mevalonate
a
concentration-dependent
manner
apoprotein
B
(apoB)-100,
marker
very
low-density
lipoprotein
(VLDL).
also
inhibited
activity
microsomal
transfer
proteins,
mediate
VLDL
formation
from
triglycerides
liver.
vivo,
accumulation
Triton
WR-1339-induced
blood
fasted
mice
maintained
low
levels
apoB-100.
These
results
suggest
that
inhibits
as
liver
has
potential
for
use
prevention
dyslipidemia.
Graphical
abstract
Язык: Английский