Glutathione-integrated waterborne polyurethanes: Aqueous dispersible, redox-responsive biomaterials for cancer drug delivery

European Polymer Journal, Год журнала: 2025, Номер unknown, С. 113759 - 113759

Опубликована: Янв. 1, 2025

Язык: Английский

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Engineering Polymers: From Biodegradable Platforms to Intelligent Drug Carriers

Polymer-Plastics Technology and Materials, Год журнала: 2025, Номер unknown, С. 1 - 27

Опубликована: Апрель 4, 2025

Язык: Английский

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Targeted Nanoparticle Delivery of Lapatinib for Cancer Therapy: Progress, Challenges, and Future Directions

Journal of Drug Delivery Science and Technology, Год журнала: 2025, Номер unknown, С. 106902 - 106902

Опубликована: Апрель 1, 2025

Язык: Английский

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Novel pH-Responsive Folic Acid-Conjugated Zein-Carboxymethyl Cellulose Nanoparticles for Enhanced and Controlled Curcumin Release

Journal of Pharmaceutical Innovation, Год журнала: 2025, Номер 20(3)

Опубликована: Май 6, 2025

Язык: Английский

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Emerging biomaterials and bio-nano interfaces in pulmonary hypertension therapy: transformative strategies for personalized treatment

Frontiers in Bioengineering and Biotechnology, Год журнала: 2025, Номер 13

Опубликована: Май 9, 2025

Pulmonary hypertension (PH) is still an aggressive and progressive illness with vascular remodeling right heart failure despite the therapeutic advances made in recent past. Biomaterials offer attractive route to break current paradigms by inducing repair, facilitating drug targeting, allowing dynamic regeneration of tissue. This review taking integrated approach investigates revolutionary role played novel biomaterials bio–nano interfaces PH treatment. We classify evaluate several classes biomaterial platforms including natural polymers, scaffolds based on synthetic extracellular vesicles (EVs), stimulus-responsive systems emphasis both underlying mechanisms clinical relevance. further address progress artificial intelligence (AI)-based integrating multi-omics tools provide patient-tailored therapy. finally touch ongoing limitations enumerate future directions required take forward biomaterial-based therapies towards reality.

Язык: Английский

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MESOPOROUS SILICA NANOPARTICLES IN SMART DRUG DELIVERY AND siRNA PRECISION THERAPY FOR CANCER: NANOMEDICINE’S NEW FRONTIER

Journal of Drug Delivery Science and Technology, Год журнала: 2025, Номер unknown, С. 107068 - 107068

Опубликована: Май 1, 2025

Язык: Английский

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pH-responsive silica nanocarriers of olaparib for augmenting anticancer activity: development, characterization, and in vitro cytotoxicity study against MCF-7 breast cancer cells

3 Biotech, Год журнала: 2025, Номер 15(6)

Опубликована: Май 27, 2025

Язык: Английский

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Polymeric nanotheranostics for solid tumor management: Recent developments and global regulatory landscape

Polymers for Advanced Technologies, Год журнала: 2024, Номер 35(6)

Опубликована: Июнь 1, 2024

Abstract Polymeric nanotheranostics have emerged as promising vehicles for diagnosis‐cum‐targeted therapy in solid tumors, offering precise delivery of therapeutic agents at the site tumors and minimizing systemic side effects. This article summarizes latest developments using polymeric nanoparticles specific treatment strategies tumors. It explores various methods these utilize targeted medication delivery. includes passive targeting through amplified permeability retention effect, active via interactions between ligands receptors, stimuli‐responsive release mechanisms such pH, temperature, enzymatic triggers. Furthermore, we highlight recent nanoparticles, which enable controlled drug response to cues tumor microenvironment, thus enhancing efficacy. Also, focus on theranostic are used diagnosing treating We discuss critical regulatory considerations bodies different countries that regulate nanomedicines' safety, efficacy, quality, manufacturing processes. Overall, this review provides insights into innovations elucidating their action, properties, pathways, collectively contribute developing effective safe nanomedicines cancer treatment.

Язык: Английский

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Dual and multiple stimuli-responsive nanocarriers for drug delivery

Elsevier eBooks, Год журнала: 2024, Номер unknown, С. 291 - 320

Опубликована: Окт. 4, 2024

Язык: Английский

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