The Utilization of Biopolymer Hydrogels to Encapsulate and Protect Probiotics in Foods

Process Biochemistry, Год журнала: 2025, Номер unknown

Опубликована: Март 1, 2025

Язык: Английский

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3D PRINTING APPLICATIONS IN THE BIOMEDICAL INDUSTRY

Gazi Üniversitesi Fen Bilimleri Dergisi Part C Tasarım ve Teknoloji, Год журнала: 2025, Номер unknown, С. 1 - 1

Опубликована: Фев. 8, 2025

Technological developments have triggered a transformation in industry, giving rise to the concept of Fourth Industrial Revolution (Industry 4.0). This has brought concepts such as rapid production, innovation, sustainability, digitalisation, personalisation and smart manufacturing forefront many sectors around world. 3D printing technologies are now staple various industries, including biomedical, due their unparalleled personalised design options, production flexibility faster product commercialisation using wide range materials. technology clearly surpassed traditional methods biomedical applications. It made it possible produce complex objects implants, prostheses, tissues organs that difficult or impossible traditionally. In addition, become precise microstructures this field cost-effective manner. study presents research into expected be indispensable future for tissue regeneration, therapeutic applications, medical device surgical planning both clinical settings. The focus is on materials been being developed highlighting processes address challenging limiting conditions improvements needed these conditions.

Язык: Английский

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Advanced Hydrogel Systems for Local Anesthetic Delivery: Toward Prolonged and Targeted Pain Relief

Gels, Год журнала: 2025, Номер 11(2), С. 131 - 131

Опубликована: Фев. 12, 2025

Local anesthetics (LAs) have been indispensable in clinical pain management, yet their limitations, such as short duration of action and systemic toxicity, necessitate improved delivery strategies. Hydrogels, with biocompatibility, tunable properties, ability to modulate drug release, extensively explored platforms for enhancing LA efficacy safety. This narrative review explores the historical development LAs, physicochemical applications, providing a foundation understanding integration hydrogels anesthetic delivery. Advances thermoresponsive, stimuli-responsive, multifunctional demonstrated significant potential prolonging analgesia reducing exposure preclinical studies, while early findings highlight feasibility thermoresponsive hydrogel formulations. Despite these advancements, challenges burst mechanical instability, regulatory considerations remain critical barriers translation. Emerging innovations, including nanocomposite hydrogels, biofunctionalized matrices, smart materials, offer solutions limitations. Future research should focus on optimizing formulations, expanding validation, integrating advanced fabrication technologies 3D printing artificial intelligence-driven design enhance personalized management. By bridging materials science pharmacology, this provides comprehensive perspective current trends future directions hydrogel-based systems.

Язык: Английский

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3D hierarchical porous hydrogel polymer electrolytes for flexible quasi-solid-state supercapacitors

Chemical Engineering Journal, Год журнала: 2025, Номер unknown, С. 161766 - 161766

Опубликована: Март 1, 2025

Язык: Английский

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Hydrogel-Based Biomaterials: A Patent Landscape on Innovation Trends and Patterns

Gels, Год журнала: 2025, Номер 11(3), С. 216 - 216

Опубликована: Март 20, 2025

The hydrogel patent landscape is characterized by rapid growth and diverse applications, particularly in the biomedical field. Advances material science, chemistry, novel manufacturing techniques, a deeper understanding of biological systems have revolutionized development hydrogel-based biomaterials. These innovations led to enhanced properties expanded regenerative medicine, drug delivery, tissue engineering, positioning hydrogels as pivotal future engineering. In this study, an updated for biomaterials proposed. By analyzing documents, classifications, jurisdictions, applicants, overview provided characterize key trends insights. analysis reveals that hydrogel-related patents are experiencing significant growth, with strong focus on applications. Foundational research formation remains dominant, 96,987 documents highlighting advancements crosslinking polysaccharide-based materials, biologically active wound care regeneration. United States China lead filings, notable contributions from Europe high number international under Patent Cooperation Treaty (PCT) system, reflecting global interest technologies. Moreover, emerging include biodegradable designed regeneration, wearable sensors, advanced therapeutic applications such chemoembolization agents vascular defect treatments. increasing integration bioactive elements driving multifunctional tailored specific medical environmental needs. While study focuses trends, alignment between patenting activities underscores role bridging scientific discoveries industrial Future could explore citation impact assessments gain insights into technological significance inventions. Finally, selection top 10 recent granted field presented illustrative example innovation area illustrate cutting-edge innovations.

Язык: Английский

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Dexketoprofen-Loaded Alginate-Grafted Poly(N-vinylcaprolactam)-Based Hydrogel for Wound Healing

International Journal of Molecular Sciences, Год журнала: 2025, Номер 26(7), С. 3051 - 3051

Опубликована: Март 26, 2025

All acute and chronic wound management strategies have limitations. Therefore, there is an urgent need to develop new treatment options for healing. Hydrogels based on natural polymers offer advantages in because they can reduce patients' pain, fight infection, carry targeted drugs speed up the healing process. In this study, we aimed investigate alginate-grafted N-vinylcaprolactam-based matrix a modified release of dexketoprofen (DEX), which potentially useful Free radical polymerization grafted techniques were used prepare thermo-responsive hydrogels. The obtained hydrogels, unloaded hydrogel (HY) dexketoprofen-loaded (DEXHY), characterized analyzed. concentration DEX encapsulated polymer was 4 mg/mL. IC50 values found samples tested by us 607.4 µg/mL HY, 950.4 DEXHY, 2239 DEX. average value cell viability (%) after exposure cells DEXHY 75.4%. exhibited very good vitro closure rate, given its ability modify kinetics. developed study has shown considerable potential facilitate even accelerate healing, including surgical wounds, inhibiting overexpressed inflammation

Язык: Английский

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Design of γ-alumina/chitosan/CeO2/SrO nanohydrogel for levofloxacin delivery

Inorganic Chemistry Communications, Год журнала: 2025, Номер unknown, С. 114557 - 114557

Опубликована: Апрель 1, 2025

Язык: Английский

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