Strontium-substituted hydroxyapatite nanoparticles associated with type I-collagen enhances the obliteration of dentinal tubules and the mineralization by human dental pulp stem cells
Jeferson Mateus Moussa Macedo,
Paula Consul Kazmirczak,
Larwsk Hayann
и другие.
Emergent Materials,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 30, 2025
Язык: Английский
S-block elements: pharmacological properties and potential medical applications of alkali and alkaline earth metals
Опубликована: Янв. 31, 2025
Background
The
periodic
table
contains
the
s-block
elements
in
groups
1
and
2.
In
table,
they
reside
first
two
columns.
S-block
consists
of
14
that
include
hydrogen
(H),
lithium
(Li),
helium
(He),
sodium
(Na),
beryllium
(Be),
potassium
(K),
magnesium
(Mg),
rubidium
(Rb),
calcium
(Ca),
cesium
(Cs),
strontium
(Sr),
francium
(Fr),
barium
(Ba),
radium
(Ra).
These
are
called
because
their
valence
electrons
s-orbital.
Alkali
alkaline
earth
metals
widely
employed
synthetic
chemical
technology.
Over
past
10
years,
a
growing
number
target
molecules
have
been
identified
chemistry
due
to
increased
attention
it
has
received
its
diverse
uses.
Methodology
Articles
were
searched
using
following
search
engines:
PubMed,
Google
Scholar,
Worldwide
Science
ResearchGate,
etc
.
Result
components
vital
life
as
essential
for
metabolism,
proteins
synthesis
brain
development.
uses
effects
alkali
medicine
research
discussed
review.
Conclusion
Lastly,
this
review
covers
historical
background
pharmacological
potential
properties,
uses,
medical
applications
such
mood
stabilization,
neuroprotection,
anti-inflammatory
activity,
diagnostic
imaging,
vasodilatory
cardioprotective
activity.
Язык: Английский
In-Vitro Biomineralization Study of Eco-Friendly Synthesized Borosilicate Glass with Strontium Oxide as dopant
S.C. Jain,
Md. Monirujjaman,
Locherla Daloji
и другие.
Ceramics International,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 1, 2025
Язык: Английский
The Effect of Different pH and Temperature Values on Ca2+, F−, PO43−, OH−, Si, and Sr2+ Release from Different Bioactive Restorative Dental Materials: An In Vitro Study
Polymers,
Год журнала:
2025,
Номер
17(5), С. 640 - 640
Опубликована: Фев. 27, 2025
Bioactive
restorative
materials
are
crucial
for
promoting
remineralization
and
protecting
dental
tissues
through
ion
release.
This
study
examines
how
pH
temperature
influence
the
short-
long-term
(F-,
Ca2+,
Sr2+,
OH-,
Si,
PO43-)
release
from
seven
commercial
materials:
Cention
Forte
Filling
Material,
Primer,
Stela
Self
Cure,
Riva
Light
Cure
HV,
Equia
HT
Fil,
Fuji
IX
GP
Fast.
Disks
were
prepared
according
to
manufacturers'
instructions;
immersed
in
buffer
solutions
at
4.8,
6.8,
8.8;
stored
37
°C
44
°C.
Ion
was
measured
after
1,
7,
28
days
using
chromatography
mass
spectrometry.
Results
revealed
that
significantly
affected
by
pH,
temperature,
exposure
time.
The
highest
fluoride
(40.14
±
0.32
mg/L)
calcium
(74.23
0.37
releases
observed
4.8
days,
with
strontium
(5.87
0.06
occurring
under
same
conditions.
In
contrast,
silicon
peaked
(31.72
0.68
These
findings
highlight
impact
of
environmental
factors
on
material
performance,
assisting
clinicians
selecting
optimal
health.
Язык: Английский
Engineered 3D-Printable Nanohydroxyapatite Biocomposites with Cold Plasma-Tailored Surface Features to Boost Osseointegration
ACS Applied Materials & Interfaces,
Год журнала:
2025,
Номер
unknown
Опубликована: Апрель 13, 2025
Medical
implants,
being
biomaterials
with
increasing
global
use,
continue
to
attract
researchers
focused
on
enhancing
clinical
performance.
In
situations
requiring
bone
substitutes,
there
is
a
search
for
advancements
in
synthetic
graft
biomaterials,
polymer-based
implants
one
of
the
potential
materials.
Thus,
this
study
aims
develop
versatile
nanohydroxyapatite
(nHAP)
biocomposites
that
can
not
only
be
generalized
by
resin
composite
systems
but
also
applicable
3D
printing,
overcoming
limitations
associated
traditional
implants.
Polymeric
are
prepared
incorporating
nHAPs
and
strontium-doped
SiO2
glass
particles
(GPs)
into
photocurable
methacrylate
monomer
system,
followed
3
min
cold
atmosphere
plasma
irradiation.
light
our
findings,
medical
implant
possesses
strong
mechanical
strength.
Its
surface
hydrophilicity
enhanced
through
treatment,
which
involves
dry
etching
nanoscale
precision
exposing
embedded
nanofillers
outmost
surface.
This
treatment
induces
osteogenic
activity
vitro
integration
vivo.
Furthermore,
printability
demonstrated
fabrication
gyroid
lattice
structure.
Collectively,
nHAP-biocomposite
exhibits
promising
biomechanical
biological
properties,
providing
revolutionizing
future
applications
dental
maxillofacial
reconstruction
as
well
orthopedic
interbody
fusion.
Язык: Английский
Investigating the early osteogenic potential of strontium doped titanium alloy surface
Journal of Applied Biomaterials & Functional Materials,
Год журнала:
2025,
Номер
23
Опубликована: Март 1, 2025
The
current
study
was
conducted
to
test
the
early
osteogenic
potential
of
strontium
(Sr)
doped
titanium-aluminum-vanadium
(Ti-6Al-4V)
alloy
using
an
in
vitro
cell
culture
experiment.
Thirty
Ti-6Al-4V
sheets
were
sandblasted
and
etched
with
large
grit
acid.
Of
these,
10
represented
group
I,
Sr
a
hydrothermal
process
II,
also
coated
Sr-supplemented
hydroxyapatite
III.
surfaces
three
groups
characterized
by
scanning
electron
microscopy
(SEM),
energy
dispersive
spectroscopy
(EDS),
X-ray
diffraction
(XRD).
compared
terms
their
water
contact
angle,
protein
adsorption,
ion
release
profile.
Further,
bone
marrow
mesenchymal
cells
(BMSCs)
obtained
from
femora
Sprague
Dawley
rats
used
for
experiment,
viability
cultured
evaluated
MTT
assay
confocal
microscopy;
addition,
assessed
alkaline
phosphatase
ALP
activity.
For
statistical
analysis,
data
analyzed
one-way
analysis
variance
(ANOVA;
IBM
SPSS
statistics
23),
p
<
0.05
considered
statistically
significant.
SEM
images
revealed
that
had
surface
roughness,
EDS
XRD
success
incorporating
surfaces.
Group
III
best
rate.
titanium
most
viable
potential;
however,
there
no
significant
difference
between
I
II.
In
Conclusion,
alone
not
able
improve
Язык: Английский
Antibacterial Ceramics for Dental Applications
Lubica Hallmann,
Mark-Daniel Gerngross
Applied Sciences,
Год журнала:
2025,
Номер
15(8), С. 4553 - 4553
Опубликована: Апрель 21, 2025
Background:
The
aim
of
this
review
was
to
evaluate
the
antibacterial
properties
functionalized
bioceramics
for
dental
applications.
Methods:
electronic
databases
PubMed,
Medline,
ProQuest,
and
Google
Scholar
were
used
search
peer-reviewed
scientific
publications
published
between
2020
2025
that
provide
insights
answer
research
questions
related
role
antibacterial-functionalized
in
combating
pathogens
dentistry
without
triggering
immune
reactions
inflammation,
as
well
on
their
efficacy
against
various
whether
understanding
mechanism
can
promote
development
glass-ceramic
bioceramic
with
long-term
activity.
keywords
were:
bioglass,
bioceramic,
biocompatible,
antibacterial,
osseointegration,
implant,
bioactive
materials.
Results:
Bacterial
infections
play
a
key
longevity
medical
devices.
A
crucial
problem
is
drug-resistant
bacteria.
Antibacterial
ceramics
have
received
great
attention
recently
because
activity,
good
mechanical
properties,
biocompatibility,
bioactivity.
This
provides
detailed
examination
complex
interactions
bacteria,
cells,
from
clinical
perspective.
focus
researchers
developing
new-generation
multifunctionality,
particular
are
independent
conventional
antibiotics.
highlight
exploration
dual
functions
such
promoting
bone
regeneration
which
potential
revolutionize
implant
technology.
Another
modifying
surface
hydrophilic
hydrophobic
order
increase
activity
bioceramics.
Conclusions:
help
understand
current
state-of-the-art
activities
bioceramics,
could
application.
Язык: Английский
Active Biomedical Materials and Their Applications
Journal of Functional Biomaterials,
Год журнала:
2024,
Номер
15(9), С. 250 - 250
Опубликована: Авг. 30, 2024
Active
biomedical
materials
are
designed
to
heal
and
restore
the
functions
of
people
recovering
after
injuries
or
diseases
[...].
Язык: Английский
Bioactive Self-Polymerizing Resin with Surface Pre-Reacted Glass Ionomer Fillers for Suppressed Enamel Demineralization
Materials,
Год журнала:
2024,
Номер
17(20), С. 5101 - 5101
Опубликована: Окт. 18, 2024
The
treatment
of
damaged
enamel
surfaces
involves
modification
the
surface
with
artificial
materials
or
development
a
pseudo-enamel,
research
focusing
on
bioactive
and
biomimetic
materials.
In
this
study,
auto-polymerizing
resin
(APR)
was
developed
by
adding
surface-pre-reacted
glass
ionomer
(S-PRG)
fillers
different
quantities
to
APR.
Its
effects
were
evaluated
via
pH
neutralization,
ion
release,
inhibition
demineralization
studies.
fluoride
release
measured
using
ion-specific
electrodes,
revealing
that
APR
disk
S-PRG
filler
immediately
neutralized
lactic
acid
solution
(pH
4.0)
through
release.
Inductively
coupled
plasma
atomic
emission
spectrometry
revealed
Sr
peaked
first
day,
other
ions
following
order
F
>
B
Si
Al
Na,
exhibiting
weekly
decrease
in
same
order.
Scanning
electron
microscopy
used
examine
block
morphology
disks
after
7
d
incubation,
without
filler,
whereas
no
occurred
filler.
containing
demonstrated
buffering
suppressed
properties.
Язык: Английский