Advances in the treatment of atherosclerotic plaque based on nanomaterials DOI

Pengyu Wang,

Weiwei Chen, Jingfeng Zhang

и другие.

Nanomedicine, Год журнала: 2025, Номер unknown, С. 1 - 13

Опубликована: Март 20, 2025

Atherosclerosis is the leading cause of cardiovascular disease worldwide, posing not only a significant threat to health but also impairing function multiple organs, with severe cases potentially being life-threatening. Consequently, effective treatment atherosclerosis paramount importance in reducing mortality associated diseases. With advancement nanomedicine and deeper understanding pathological mechanisms underlying atherosclerosis, nanomaterials have emerged as promising platforms for precise diagnosis targeted therapeutic strategies. These materials offer notable advantages, including drug delivery, enhanced bioavailability, improved stability, controlled release. This review provides an overview atherosclerotic plaque development examines nanomaterial-based approaches managing plaques, therapies targeting cholesterol metabolism, anti-inflammatory strategies, macrophage clearance, immunotherapy. Additionally, paper discusses current technical challenges clinical transformation these therapies. Finally, potential future integration nanomaterials, smart artificial intelligence explored.

Язык: Английский

Advances in the treatment of atherosclerotic plaque based on nanomaterials DOI

Pengyu Wang,

Weiwei Chen, Jingfeng Zhang

и другие.

Nanomedicine, Год журнала: 2025, Номер unknown, С. 1 - 13

Опубликована: Март 20, 2025

Atherosclerosis is the leading cause of cardiovascular disease worldwide, posing not only a significant threat to health but also impairing function multiple organs, with severe cases potentially being life-threatening. Consequently, effective treatment atherosclerosis paramount importance in reducing mortality associated diseases. With advancement nanomedicine and deeper understanding pathological mechanisms underlying atherosclerosis, nanomaterials have emerged as promising platforms for precise diagnosis targeted therapeutic strategies. These materials offer notable advantages, including drug delivery, enhanced bioavailability, improved stability, controlled release. This review provides an overview atherosclerotic plaque development examines nanomaterial-based approaches managing plaques, therapies targeting cholesterol metabolism, anti-inflammatory strategies, macrophage clearance, immunotherapy. Additionally, paper discusses current technical challenges clinical transformation these therapies. Finally, potential future integration nanomaterials, smart artificial intelligence explored.

Язык: Английский

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