Structural and functional characterisation and regulatory mechanisms of SWI/SNF and RSC chromatin remodelling complexes in fungi DOI Creative Commons
Lirong Zhu, Qianqian Liu, Chao Zhao

и другие.

Mycology&#58 An International Journal on Fungal Biology, Год журнала: 2025, Номер unknown, С. 1 - 23

Опубликована: Янв. 6, 2025

Chromatin remodellers utilise energy generated from ATP hydrolysis to remodel nucleosomes and modulate histones, which are crucial for eukaryotic gene expression chromatin architecture. The SWI/SNF (switching defective/sucrose non-fermenting) class of ATP-dependent modifiers in eukaryotes includes two complexes, RSC (remodeling the structure chromatin). In past 10 years, have been a focus research various organisms, including animals, plants fungi. fungi, these complexes multiple functions, roles regulating hyphal differentiation, sporulation, stress responses, pathogenicity. addition describing conserved structural properties mechanisms action, we highlight evidence sequence functional divergence fungal evolution. This review provides basis further comparative analyses regulatory taxonomically diverse laying good foundation potential applications controlling pathogenic

Язык: Английский

Structural and functional characterisation and regulatory mechanisms of SWI/SNF and RSC chromatin remodelling complexes in fungi DOI Creative Commons
Lirong Zhu, Qianqian Liu, Chao Zhao

и другие.

Mycology&#58 An International Journal on Fungal Biology, Год журнала: 2025, Номер unknown, С. 1 - 23

Опубликована: Янв. 6, 2025

Chromatin remodellers utilise energy generated from ATP hydrolysis to remodel nucleosomes and modulate histones, which are crucial for eukaryotic gene expression chromatin architecture. The SWI/SNF (switching defective/sucrose non-fermenting) class of ATP-dependent modifiers in eukaryotes includes two complexes, RSC (remodeling the structure chromatin). In past 10 years, have been a focus research various organisms, including animals, plants fungi. fungi, these complexes multiple functions, roles regulating hyphal differentiation, sporulation, stress responses, pathogenicity. addition describing conserved structural properties mechanisms action, we highlight evidence sequence functional divergence fungal evolution. This review provides basis further comparative analyses regulatory taxonomically diverse laying good foundation potential applications controlling pathogenic

Язык: Английский

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