Edible Mushroom Bioactive Compounds and Neurogenic Diseases

Reference series in phytochemistry, Год журнала: 2025, Номер unknown, С. 1 - 37

Опубликована: Янв. 1, 2025

Язык: Английский

---

Lectins purified from medicinal and edible mushrooms: Insights into their antiviral activity against pathogenic viruses

International Journal of Biological Macromolecules, Год журнала: 2021, Номер 179, С. 239 - 258

Опубликована: Март 5, 2021

Язык: Английский

---

Mushroom β-glucan and polyphenol formulations as natural immunity boosters and balancers: nature of the application

Food Science and Human Wellness, Год журнала: 2022, Номер 12(2), С. 378 - 396

Опубликована: Сен. 7, 2022

Mushrooms are experiencing a kind of renaissance as part the contemporary human diet. These valuable organisms more than food, they fit in perfectly novel market group known nutra-mycoceuticals. Immune-balancing mushroom dietary fibers and secondary metabolites such polyphenols main focus healthcare industry. Wellness cosmetic companies increasingly using extracts rich these ingredients. This review considers basic molecular immunomodulatory mechanisms action most commonly used fibers, β-glucans. The literature data on their bioavailability, metabolic transformations, preclinical clinical research, safety discussed. Immunomodulatory polyphenol ingredients also considered. molecules present great potential design new immunity balancer formulations according to widespread structural diversity. Finally, we draw attention perspectives modern trends nutraceutical cosmeceutical strengthen balance immunity.

Язык: Английский

---

Edible Mushrooms as Novel Myco-Therapeutics: Effects on Lipid Level, Obesity and BMI

Journal of Fungi, Год журнала: 2022, Номер 8(2), С. 211 - 211

Опубликована: Фев. 21, 2022

Obesity, usually indicated by a body mass index of more than 30 kg/m

Язык: Английский

---

Anti-Cancer Potential of Edible/Medicinal Mushrooms in Breast Cancer

International Journal of Molecular Sciences, Год журнала: 2023, Номер 24(12), С. 10120 - 10120

Опубликована: Июнь 14, 2023

Edible/medicinal mushrooms have been traditionally used in Asian countries either the cuisine or as dietary supplements and nutraceuticals. In recent decades, they aroused increasing attention Europe well, due to their health nutritional benefits. particular, among different pharmacological activities reported (antibacterial, anti-inflammatory, antioxidative, antiviral, immunomodulating, antidiabetic, etc.), edible/medicinal shown exert vitro vivo anticancer effects on several kinds of tumors, including breast cancer. this article, we reviewed showing antineoplastic activity again cancer cells, especially focusing possible bioactive compounds involved mechanisms action. following considered: Agaricus bisporus, Antrodia cinnamomea, Cordyceps sinensis, militaris, Coriolus versicolor, Ganoderma lucidum, Grifola frondosa, Lentinula edodes, Pleurotus ostreatus. We also report insights into relationship between consumption edible risk, results clinical studies meta-analyses fungal extracts patients.

Язык: Английский

---

Macrofungi as Medicinal Resources in Uzbekistan: Biodiversity, Ethnomycology, and Ethnomedicinal Practices

Journal of Fungi, Год журнала: 2023, Номер 9(9), С. 922 - 922

Опубликована: Сен. 13, 2023

Interest in edible and medicinal macrofungi is millennial terms of their uses health food products Central Asia, while interest inedible has grown popularity recent years. Edible basidiomycetes were collected during field surveys from different regions Uzbekistan. The morphological characters similarity assessment rDNA-Internal Transcribed Spacer sequence data used to measure diversity habitat associations. A number 17 species ethnomycological was found associated with 23 trees shrubs belonging 11 families 14 genera. Polyporaceae Hymenochaetaceae represented by the highest followed Ganodermataceae, Fomitopsidaceae, Auriculariaceae, Cerrenaceae, Grifolaceae, Phanerochaetaceae, Laetiporaceae, Schizophyllaceae, Stereaceae. basidiomycete reported following host genera: Acer, Betula, Celtis, Crataegus, Juglans, Juniperus, Lonicera, Malus, Morus, Platanus, Populus, Prunus, Quercus, Salix. An updated list mushrooms identified Uzbekistan, characteristics, phylogenetic placement are given for first time. Information provided on traditional modern medicine. Their bioactive compounds extracts can be applied as medicines, well cosmetic ingredients.

Язык: Английский

---

A review for cancer treatment with mushroom metabolites through targeting mitochondrial signaling pathway: In vitro and in vivo evaluations, clinical studies and future prospects for mycomedicine

Fitoterapia, Год журнала: 2023, Номер 172, С. 105681 - 105681

Опубликована: Сен. 23, 2023

Resistance to apoptosis stands as a roadblock the successful pharmacological execution of anticancer drug effect. A comprehensive insight into apoptotic signaling pathways and an understanding mechanisms resistance are crucial unveil new targets. At this juncture, researchers heading towards natural sources in particular, mushroom their potential drugs leads being reliable source potent bioactive compounds. Given continuous increase cancer cases, efficacy mushrooms has inevitably become fascinating object due higher safety margin multitarget. This review aimed collect summarize all available scientific data on with from extracts molecules order suggest attributes via mitochondrion -mediated intrinsic mechanism. Compiled revealed that components including polysaccharides, sterols terpenoids well prepared using 15 different solvents 53 species could be effective supportive treatment 20 various cancers. The underlying therapeutic studied explored through diverse complementary investigations: vitro assays, pre-clinical studies clinical randomized controlled trials. processes mainly involved were ROS production, mitochondrial membrane dysfunction, action caspase 3, 9, XIAP, cIAP, p53, Bax, Bcl-2. In summary, study provides facts pertaining beneficial effect active compounds against types is shedding light targeted pathways.

Язык: Английский

---

Termite Mushrooms (Termitomyces), a Potential Source of Nutrients and Bioactive Compounds Exhibiting Human Health Benefits: A Review

Journal of Fungi, Год журнала: 2023, Номер 9(1), С. 112 - 112

Опубликована: Янв. 13, 2023

Termite mushrooms have been classified to the genus

Язык: Английский

---

Eco-friendly, bright luminescent carbon dots and their potential applications for detecting hypochlorous acid in water and live cell imaging

Journal of Materials Research and Technology, Год журнала: 2023, Номер 24, С. 6522 - 6532

Опубликована: Май 1, 2023

In this study, we utilized Agaricaceae, or mushrooms, as the carbon source for hydrothermal production of multifunctional dots (MCDs). The MCDs showed remarkable features such bright blue fluorescence, exceptional biocompatibility, high quantum yield, and efficient biolabeling ability. Moreover, displayed extraordinary specificity towards HOCl, could detect it in deionized water with a lower detection limit 3.38 nM. Additionally, had potent antioxidant properties, low cytotoxicity, cell permeability, confirmed by DPPH reducing potential analysis. Furthermore, MCD probe proved to be highly useful various biological applications, including endogenous HOCl RAW 264.7 line assessment PMA-induced formation using confocal imaging. synthesis (CDs) from natural resource mushrooms is promising prospect due their physicochemical properties broad range applications.

Язык: Английский

---

Structural properties and anti-inflammatory activity of purified polysaccharides from Hen-of-the-woods mushrooms (Grifola frondosa)

Frontiers in Nutrition, Год журнала: 2023, Номер 10

Опубликована: Фев. 7, 2023

Grifola frondosa is an edible medicinal mushroom that has been proven to have a variety of health benefits. The main active ingredients this are polysaccharides. In study, ultrasonic-assisted extraction was used obtain crude polysaccharides (GFPs). Then, purified GFP obtained after purification. optimum conditions were time 71 min, temperature 90°C in solid-to-liquid ratio 1:37 g/mL, and ultrasonic power 500 W. using DEAE-52 Sephadex G-100. structural characterization performed Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), ion chromatography (IC), ultraviolet (UV) visible photometry. morphology analyzed by scanning electron microscopy (SEM), thermogravimetric differential calorimetry (TG-DSC), Congo red testing. addition, the administration oxazolone (OXZ)-induced ulcerative colitis (UC) mice found prevent weight loss. Different doses (80, 160, 320 mg/kg body weight) used, sulfapyridine (SASP) as positive control (370 for treatment OXZ-induced UC. After treatment, killed, blood colon tissue samples collected. decreases length levels leukocytes, platelets, neutrophils UC mice. Moreover, also decreased expression pro-inflammatory cytokines [tumor necrosis factor (TNF)-α interleukin (IL)-1 β], increased IL-10, reduced injury results showed Under these conditions, predicted polysaccharide yield 21.72%, actual rate 21.13%. composition (molar ratio) composed fucose (0.025), glucosamine hydrochloride (0.004), galactose (0.063), glucose (0.869), mannose (0.038). typical absorption peak, extracted ultrasound-assisted protocol mainly β-glucan. These indicate could reduce intestinal inflammation promising candidate UC, with potential development food supplement improve diseases.

Язык: Английский

---