Phylogenomics, divergence times and notes of orders in Basidiomycota

Fungal Diversity, Год журнала: 2024, Номер 126(1), С. 127 - 406

Опубликована: Июль 9, 2024

Язык: Английский

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Annotated Checklist of Poroid Hymenochaetoid Fungi in Central Asia: Taxonomic Diversity, Ecological Roles, and Potential Distribution Patterns

Journal of Fungi, Год журнала: 2025, Номер 11(1), С. 37 - 37

Опубликована: Янв. 5, 2025

Central Asia, located at the heart of Eurasia, is renowned for its varied climate and vertical vegetative distribution, which support diverse biomes position it as a global biodiversity hotspot. Despite this ecological richness, Asia’s fungal diversity, particularly wood-inhabiting macrofungi, remains largely unexplored. This study investigates roles, potential distribution poroid Hymenochaetoid fungi in region. By conducting field surveys, collecting basidiomes, reviewing literature herbarium records from five Asian countries, we compiled comprehensive checklist these fungi. In total, 43 species belonging to 18 genera were identified, with Inonotus, Phellinus, Phylloporia being most species-rich. Notably, Inonotus hispidus Phellinus igniarius found be widespread species. These macrofungi play essential roles saprotrophs pathogens various identified host plant families, aiding lignin degradation exhibiting enzymatic activities. For first time, modelled patterns revealing that their strongly influenced by availability temperature-related factors. The three critical variables density, annual temperature range (Bio7), mean warmest quarter (Bio10). suitable habitats uneven, highly areas (4.52%) concentrated mountainous border regions between Kazakhstan, Kyrgyzstan, Tajikistan, Uzbekistan. results underscore significance specific environmental conditions growth survival Our findings highlight urgent need continued mycological research expanded conservation initiatives document preserve macrofungal botanical under-explored area. light change, collected data provide valuable reference promoting forest health management globally.

Язык: Английский

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Exploring biodiversity and ethnobotanical significance of Solanum species in Uzbekistan: unveiling the cultural wealth and ethnopharmacological uses

Frontiers in Pharmacology, Год журнала: 2024, Номер 14

Опубликована: Янв. 24, 2024

Despite its millennial existence and empirical documentation, the ethnological knowledge of herbs is a more recent phenomenon. The their historical uses as food, medicine, source income small-scale businesses, sociological impacts are threatened due to slow ethnobotanical research drive. Species genus Solanum have long been extensively used in folk medicine treat various illnesses humans since dawn civilization. All data were systematically obtained from papers, monographs, books written Uzbek, Russian, English through scientific online databases, including Google, Google Scholar, PubMed, Scopus, Semantic Science Direct, Web using specific keywords focused on eight species. Eight native non-native species S. dulcamara L., lycopersicum melongena nigrum rostratum Dunal., sisymbriifolium Lam., tuberosum villosum Mill. recorded Uzbekistan Central Asia. In this article we presented recently diversity, morphological characteristics, global distribution, habitat, population status, phenology, reproduction, pharmacology phytochemistry these Uzbekistan. Furthermore, relying combination literature reviews analyses focus food consumption coupled with ethnopharmacological human diseases growing Since civilization, cultivated non-cultivated provided sustainable resources medicinal plants prevent diseases. Based collected data, it was shown that not studied ethnobotanically ethnomedicinally necessary conduct phytochemical biotechnological them future. Traditional evaluation indicate , one most widely some parts world. Although considerable progress has made comprehend chemical biological properties species, toxicology needed ensure safety, efficacy, quality biologically active extracts isolated bioactive compounds. Additionally, conducting additional structure-activity relationship certain phytochemicals potential enhance efficacy advance utilization traditional applications taxa.

Язык: Английский

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Exploring the health benefits of Ganoderma : bioactive compounds and mechanisms of action; immunomodulatory, and anti-tumour activities

New Zealand Journal of Botany, Год журнала: 2024, Номер unknown, С. 1 - 85

Опубликована: Июль 22, 2024

Ganoderma, a genus of mushrooms known for its long history medicinal use, has gained increasing attention in recent years due to potential health benefits. This review delves into the bioactive compounds found Ganoderma and elucidates intricate mechanisms underlying immunomodulatory anti-tumour activities. The diverse health-promoting effects can be attributed decadent array compounds, notably polysaccharides, triterpenoids, which play pivotal role. ability mushroom modulate immune system, enhancing activity cells, such as natural killer cells macrophages, is central focus. Furthermore, we explore how exerts through induction apoptosis, inhibition angiogenesis, interference with various signalling pathways critical cancer cell growth metastasis. As research this area continues evolve, comprehensive understanding supplement role promoting well-being emerging, offering promising avenues further investigation application healthcare.

Язык: Английский

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“But how true that is, I do not know”: the influence of written sources on the medicinal use of fungi across the western borderlands of the former Soviet Union

IMA Fungus, Год журнала: 2024, Номер 15(1)

Опубликована: Авг. 5, 2024

Fungi have been used for medicinal purposes many centuries. This study, based on 35 historical written sources and 581 in-depth semi-structured interviews from eight countries in the western borderlands of former Soviet Union, investigates use fungi by local communities. We compared taxa uses obtained fieldwork with works that advocated within herbals, representing centralised medical system. During fieldwork, we identified locally one lichen. The highest numbers were documented Russia, Estonia Ukraine. Studies published before era listed 21 fungal lichen species study region. However, only six these mentioned as people our field studies (Amanita muscaria, Boletus edulis, Lycoperdon, Morchella, Phallus impudicus Cetraria islandica). Notably, same consistently endorsed herbals. Of remaining three recorded none sources. they promoted either herbals (Inonotus obliquus, Kombucha) or later popular publications (Cantharellus cibarius). highlights significant influence studied

Язык: Английский

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Ex Situ Conservation, DNA Barcoding and Enzymatic Potential Evaluation of Macrofungi (Basidiomycota, Ascomycota) from Vietnam

Journal of Fungi, Год журнала: 2025, Номер 11(1), С. 34 - 34

Опубликована: Янв. 4, 2025

The diversity and resource potential of macroscopic fungi in tropical regions remain understudied. Vietnam, being a biodiversity hotspot, has large number new fungal species that are interest for biotechnology medicine. presence protected areas Vietnam creates favorable opportunities the study ex situ conservation biodiversity. From 2012 to 2023, 785 strains macrofungi from National Parks were preserved LE-BIN collection, 327 which barcoded with sequences deposited NCBI GenBank. A taxonomic analysis demonstrated many isolates potentially or poorly studied species, representing useful taxonomical studies search medicinal mushrooms. More than 180 first time growth rate enzymatic activities. Of these, 53 showed high rate, 43-high cellulolytic activity, 73-high oxidative enzymes 27 proteolytic making them promising candidates biotechnological medical applications opening sustainable biomass management, discovery bioactive substances, development drugs efficient plant waste treatment technologies. results confirm importance as valuable source scientific commercial suggest certain active study.

Язык: Английский

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UPLC-MS metabolite profiling and antioxidant activity of Sanghuangporus sanghuang extract

PeerJ, Год журнала: 2025, Номер 13, С. e18758 - e18758

Опубликована: Янв. 22, 2025

Background The objective of the present study is to examine total phenolic and flavonoid content an ethanol extract Sanghuangporus sanghuang evaluate its phytochemical properties, antioxidant activity, capacity protect DNA from damage. This pharmaceutical/food resource mushroom may serve as a novel substitute functional food for health-conscious consumers, given promising source phenolics flavonoids. Methods S. (SEE) was evaluated contents, while UPLC-MS analysis used terpenoids, phenylpropanoid, flavonoids, steroidal, phenols identification, function prediction. Antioxidant anti-DNA damage activities were tested in vitro using ferric reducing power (FRAP), 1,1-diphenyl-2-picrylhydrazyl (DPPH), 2,2′-azino-bis-3-ethylbenzotiazolin-6-sulfonic acid (ABTS), protection assay. Results Conclusion Total (TPC) SEE 385.38 ± 1.36 mg GA/g extract, (TFC) 298.22 2.38 QE/g extract. extracts exhibited high free radical scavenging with relatively stronger activity. A 491 metabolites investigated by Ultra-performance liquid chromatography-mass spectrometry (UPLC-MS). Most top 20 compounds predicted have various functions like antioxidant, anti-cancer anti-inflammatory. highlighted beneficial It contains potential natural that could be lead contender development medicines treatment wide range oxidative stress-related illnesses.

Язык: Английский

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Comparative evaluation of free radical scavenging activity and total metabolite profiles among 30 macrofungi species

Bioresources and Bioprocessing, Год журнала: 2025, Номер 12(1)

Опубликована: Фев. 21, 2025

Abstract The high antioxidant content of mushrooms such as polyphenols, polysaccharides, carotenoids, ergothioneine, glutathione, vitamins, and other compounds, has sparked interest in their potential use preventive therapeutic medicine. Therefore, this study aimed to evaluate the various macrofungi by measuring 1,1-diphenyl-2-picryl-hydrazyl (DPPH) radical scavenging activity quantifying two classes compounds: phenolics (TPC) both endo- (IPS) exopolysaccharides (EPS). Species-specific abilities produce mycelium, polyphenols were observed under submerged cultivation without agitation over 14 days. Mycelium productivity (P M ) ranged significantly from 292 ± 11 1110 37 mg·L⁻ 1 ·day⁻ , with highest values Ophiocordyceps sinensis (1110 ), Pleurotus djamor (1090 Cordyceps militaris (1080 90 mg· L⁻ ). DPPH inhibition extracts varied 4.30 0.20 87.9 0.80%, while TPC 0.35 0.10 34.6 0.80 mg GAE/g d.w. Lentinula edodes was best source produced IPS (10.3 g·L −1 Hypsizygus marmoreus exhibited EPS (2.24 0.30 Overall, levels across species higher, ranging 1.56 10.3 . In half fungal species, mycelium superior compared culture broth. However, majority (66.7%), higher broth than mycelium. Distinct metabolite profiles among different isolates. Notably, Fomitopsis pinicola L. showed TPC. depending on medium, solvents used. (90%) (38.5 0.40 d.w.) methanol (MeOH) extract F. grown Sabouraud dextrose medium. Similarly, MeOH ethyl acetate (EtOAc) demonstrated strong (over 87%), maximum (40.0 0.60 detected water (H 2 O) cultivated glucose-peptone-yeast A positive correlation found between activity, Pearson’s coefficient 0.6615 for 0.1192 broth, 0.8924 0.7143 respectively. Both exhibit significant natural antioxidants. These can be applied nutraceuticals, food products, nutritional supplements, offering diverse health benefits. Additionally, is a pioneering exploration Auriporia aurea Hohenbuehelia myxotricha Lepista luscina Oxyporus obducens Pseudospongipellis litschaueri highlighting largely unexplored applications. Graphical

Язык: Английский

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Mycochemistry, Traditional Uses, and Nutraceutical Potential of Laricifomes officinalis: A Biotechnological and Pharmacological Perspective

Plant Foods for Human Nutrition, Год журнала: 2025, Номер 80(1)

Опубликована: Фев. 24, 2025

Язык: Английский

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Bioactivity profiling of Sanghuangporus lonicerinus : antioxidant, hypoglycaemic, and anticancer potential via in-vitro and in-silico approaches

Journal of Enzyme Inhibition and Medicinal Chemistry, Год журнала: 2025, Номер 40(1)

Опубликована: Фев. 24, 2025

This study investigates the mycochemical profile and biological activities of hydroethanolic (EtOH), chloroform (CHCl3), hot water (H2O) extracts Sanghuangporus lonicerinus from Uzbekistan. Antioxidant capacity was assessed using 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2′-azino-bis-3-ethylbenzothiazoline-6-sulfonic acid (ABTS), NO, FRAP assays, in vitro hypoglycaemic effects were evaluated through α-amylase α-glucosidase inhibition. Antiproliferative potential explored by analysing binding affinities EtOH H2O to estrogen receptor α (ERα), ERβ, androgen (AR), glucocorticoid (GR), with molecular docking providing structural insights. LC-MS/MS analysis revealed solvent-dependent phenolic profiles, extract containing highest total content (143.15 ± 6.70 mg GAE/g d.w.) best antioxidant capacity. The showed significant effects, 85.29 5.58% inhibition 41.21 0.79% α-amylase. Moderate ERβ suggests for estrogen-mediated cancer therapy, while strong AKR1C3 supports its therapeutic potential.

Язык: Английский

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