The enigma of maladaptation in gastric pathophysiology DOI Creative Commons
Gunter Maubach, Anumantha G. Kanthasamy,

Sudhanshu Gogia

и другие.

Trends in cancer, Год журнала: 2025, Номер unknown

Опубликована: Фев. 1, 2025

Despite a decline in global incidence, gastric cancer (GC) remains major health concern. The development of GC is sequential, multistage maladaptive process involving numerous different factors. Understanding the complexity crucial for early detection, effective treatment, and, ultimately, prevention. In this respect, identifying impact risk factors contributing to emergence or progression GC, such as Helicobacter pylori infection, host and bacterial genetics, alcohol consumption, smoking, preserved foods, will aid combatting disease. review, we focus on recent developments understanding role microbiome, dysfunctional molecular pathways, immune evasion pathophysiology. We also highlight challenges advances treatment GC.

Язык: Английский

The enigma of maladaptation in gastric pathophysiology DOI Creative Commons
Gunter Maubach, Anumantha G. Kanthasamy,

Sudhanshu Gogia

и другие.

Trends in cancer, Год журнала: 2025, Номер unknown

Опубликована: Фев. 1, 2025

Despite a decline in global incidence, gastric cancer (GC) remains major health concern. The development of GC is sequential, multistage maladaptive process involving numerous different factors. Understanding the complexity crucial for early detection, effective treatment, and, ultimately, prevention. In this respect, identifying impact risk factors contributing to emergence or progression GC, such as Helicobacter pylori infection, host and bacterial genetics, alcohol consumption, smoking, preserved foods, will aid combatting disease. review, we focus on recent developments understanding role microbiome, dysfunctional molecular pathways, immune evasion pathophysiology. We also highlight challenges advances treatment GC.

Язык: Английский

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