Bringing Lab to the Field: Exploring Innovations in Point-of-Care Diagnostics for the Rapid Detection and Management of Tropical Diseases in Resource-Limited Settings
Advances in Biomarker Sciences and Technology,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 1, 2025
Язык: Английский
A Review on Optical Biosensors for Monitoring of Uric Acid and Blood Glucose Using Portable POCT Devices: Status, Challenges, and Future Horizons
Biosensors,
Год журнала:
2025,
Номер
15(4), С. 222 - 222
Опубликована: Март 31, 2025
The
growing
demand
for
real-time,
non-invasive,
and
cost-effective
health
monitoring
has
driven
significant
advancements
in
portable
point-of-care
testing
(POCT)
devices.
Among
these,
optical
biosensors
have
emerged
as
promising
tools
the
detection
of
critical
biomarkers
such
uric
acid
(UA)
blood
glucose.
Different
transduction
methods,
like
fluorescence,
surface
plasmon
resonance
(SPR),
colorimetric
approaches,
are
talked
about,
with
a
focus
on
how
sensitive,
specific,
they
are.
Despite
considerable
advancements,
several
challenges
persist,
including
sensor
stability,
miniaturization,
interference
effects,
need
calibration-free
operation.
This
review
also
explores
issues
related
to
cost-effectiveness,
data
integration,
wireless
connectivity
remote
monitoring.
further
examines
regulatory
considerations
commercialization
aspects
biosensors,
addressing
gap
between
research
developments
clinical
implementation.
Future
perspectives
emphasize
integration
artificial
intelligence
(AI)
healthcare
improved
diagnostics,
alongside
development
wearable
implantable
continuous
Innovative
potential
change
way
people
manage
their
by
quickly
accurately
measuring
glucose
levels.
is
especially
true
decentralized
solutions
grows.
By
critically
evaluating
existing
work
exploring
limitations
opportunities
field,
this
will
help
guide
more
efficient,
accessible,
reliable
POCT
devices
that
can
improve
patient
outcomes
quality
life.
Язык: Английский
Utilization and benefits of point-of-care testing in primary healthcare
Mohammed Al Jumah,
Fisal F. Magliah,
Salman A. Ageel
и другие.
International Journal of Community Medicine and Public Health,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 24, 2025
Point-of-care
testing
(POCT)
represents
a
transformative
advancement
in
healthcare,
enabling
rapid
and
accurate
diagnostics
at
or
near
the
site
of
patient
care.
By
reducing
reliance
on
centralized
laboratories,
POCT
expedites
clinical
decision-making
enhances
healthcare
delivery,
particularly
underserved
regions.
Its
application
spans
various
medical
fields,
including
infectious
diseases,
chronic
disease
management,
emergency
Innovations
such
as
molecular
diagnostics,
biosensors,
artificial
intelligence
(AI)
integration
have
improved
precision,
reliability,
accessibility
devices,
offering
significant
benefits
for
outcomes
efficiency.
has
demonstrated
its
potential
to
reduce
diagnostic
delays,
lower
hospital
admissions,
decrease
burden
overextended
systems.
Rapid
conditions
acute
myocardial
infarction,
diabetes,
malaria
resulted
timely
interventions,
improving
survival
rates
complications.
In
addition
benefits,
economic
analyses
highlight
cost-effectiveness
POCT,
it
minimizes
resource
utilization
shortens
treatment
cycles.
However,
challenges
persist
scaling
accessibility.
Financial
barriers,
supply
chain
limitations,
regulatory
inconsistencies,
workforce
training
deficits
impede
widespread
adoption,
low-
middle-income
countries.
Addressing
these
issues
requires
innovative
funding
models,
global
harmonization,
capacity-building
initiatives
empower
workers.
Technological
advancements
continue
expand
POCT's
potential,
integrating
real-time
with
digital
health
platforms
epidemiological
surveillance
These
developments
promise
not
only
enhance
delivery
but
also
improve
public
responses
outbreaks
crises.
bridging
gap
between
treatment,
offers
pathway
more
equitable
efficient
systems,
transforming
how
where
care
is
delivered.
into
frameworks
holds
redefine
care,
fostering
future
accessible,
high-quality
all.
Язык: Английский
Metal–Organic Frameworks Meet Two‐Dimensional Materials in Polymer Matrices for Flame Retardant and Sensor Applications
Small Science,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 21, 2025
Functional
polymer
composites
offer
versatility
and
high
performance
through
material
fusion,
but
flammability
is
an
obstacle
to
application.
Metal–organic
frameworks
(MOFs)
have
attracted
attention
in
the
field
of
flame
retardant
due
their
structural
diversity
specific
surface
area,
they
suffer
from
low
efficiency
agglomeration
issues
when
used
alone.
Combining
with
two‐dimensional
(2D)
nanomaterials
can
improve
above
situation.
Herein,
strategies
are
explored
for
integrating
MOFs
2D
materials
physical
mixing
situ
growth
enhance
dispersion
flame‐retardant
effects
polymers.
Additionally,
integration
sensing
achieve
intelligent
monitoring
control,
as
well
real‐time
risk
assessment
system
optimization.
In
summary,
this
review
deeply
analyzes
dispersion,
interfacial
interaction,
adjustment
mechanism
composite
discusses
detail
application
potential
hybrids
formed
by
sensing.
Finally,
opportunities
challenges
faced
functional
future
summarized
prospected.
it
also
expected
facilitate
researchers
quickly
understand
latest
developments
guide
effective
design.
Язык: Английский
Challenges and Applications of Bio-Sniffers for Monitoring Volatile Organic Compounds in Medical Diagnostics
Chemosensors,
Год журнала:
2025,
Номер
13(4), С. 127 - 127
Опубликована: Апрель 3, 2025
Bio-sniffers
represent
a
novel
detection
technology
that
demonstrates
significant
potential
in
medical
diagnostics.
Specifically,
they
assess
disease
conditions
and
metabolic
status
through
the
of
volatile
organic
compounds
(VOCs)
exhaled
breath.
Unlike
conventional
methods
such
as
gas
chromatography-mass
spectrometry
(GC-MS)
chromatography
time-of-flight
mass
(GC-TOF-MS),
bio-sniffers
provide
rapid,
sensitive,
portable
capabilities.
In
this
review,
we
examine
pathways
specific
VOCs
human
body,
their
roles
biomarkers,
focus
on
principles,
performance
characteristics,
applications
two
bio-sniffer
types:
electrical
optical
sensors.
Finally,
systematically
discuss
current
challenges
facing
VOC
monitoring,
outline
future
development
directions,
suggestions
for
improving
sensitivity
reducing
environmental
interference.
Язык: Английский