Eurasian journal of applied biotechnology,
Год журнала:
2023,
Номер
4, С. 55 - 63
Опубликована: Дек. 28, 2023
Walnut
(Juglans
Regia
L.)
is
a
promising
plant
for
use
in
modern
medicine.
We
describe
the
reactions
of
Juglans
L.
microclones
exposed
to
cold
stress
vitro
at
cell
and
tissue
level.
Differences
water
content
tissues
anatomical
morphological
structure
stem
leaf
under
control
conditions
are
shown.
Significant
changes
parameters
various
tissues,
both
upward
downward,
tendency
values
decrease
were
revealed.
It
has
been
suggested
that
characteristics
organs
may
affect
phytochemical
biologically
active
substances
them,
valuable
pharmacy.
Nutrients,
Год журнала:
2023,
Номер
15(15), С. 3448 - 3448
Опубликована: Авг. 4, 2023
A
range
of
natural
products
have
been
extensively
studied
for
their
chemopreventive
potential
cancer,
including
those
that
inhibit
growth
and
induce
apoptosis.
Sidr
honey
derived
from
the
Ziziphus
or
Lote
tree
(Ziziphus
spina-christi,
lotus,
jujuba)
is
used
in
a
wide
traditional
medicine
practices.
In
current
study,
Saudi
was
analyzed
by
means
GC-MS
chromatogram
investigated
its
antiproliferative
effects
on
colorectal
cancer
cells
(HCT-116),
breast
(MCF-7),
lung
(A-549),
as
well
apoptosis
induction
cell
cycle
arrest
potentials
against
human
(HCT-116).
The
were
determined
using
MTT
assay
clonogenic
assay.
Annexin
V-FITC
flow
cytometry
analysis.
propidium
iodide
staining
method
to
detect
via
cytometry.
By
performing
GS-MS
HR-LCMS
analysis,
23
different
chemical
components
identified
honey.
dose-response
analysis
showed
more
effective
HCT-116
(IC50
=
61.89
±
1.89
µg/mL)
than
MCF-7
78.79
1.37
A-549
94.99
1.44
µg/mL).
antiproliferation
activity
has
found
be
linked
aggregation
during
G1
phase,
an
increase
early
late
apoptosis,
necrotic
death
cells.
Considering
these
promising
findings
highlight
use
antitumor
agent,
further
research
should
carried
out
with
aim
isolating,
characterizing,
evaluating
bioactive
compounds
involved
honey's
better
understand
mechanism
action.
International Journal of Molecular Sciences,
Год журнала:
2024,
Номер
25(9), С. 4991 - 4991
Опубликована: Май 3, 2024
The
current
study
investigated
the
impact
of
cold
stress
on
morphological,
physiological,
and
phytochemical
properties
Juglans
regia
L.
(J.
regia)
using
in
vitro
microclone
cultures.
revealed
significant
stress-induced
changes
production
secondary
antioxidant
metabolites.
According
to
gas
chromatography–mass
spectrometry
(GC–MS)
analyses,
conditions
profoundly
altered
metabolism
J.
microclones.
Although
overall
spectrum
metabolites
was
reduced,
key
significantly
increased.
Notably,
there
a
sevenfold
(7×)
increase
juglone
concentration.
These
findings
are
crucial
for
advancing
walnut
metabolomics
enhancing
our
understanding
plant
responses
abiotic
factors.
Additionally,
results
aid
identifying
role
individual
these
processes,
which
is
essential
developing
strategies
improve
resilience
tolerance
adverse
conditions.
Journal of Functional Biomaterials,
Год журнала:
2023,
Номер
14(4), С. 221 - 221
Опубликована: Апрель 14, 2023
Aflatoxins
produced
by
some
species
of
Aspergillus
are
considered
secondary
toxic
fungal
by-products
in
feeds
and
food.
Over
the
past
few
decades,
many
experts
have
focused
on
preventing
production
aflatoxins
ochraceus
also
reducing
its
toxicity.
Applications
various
nanomaterials
these
received
a
lot
attention
recently.
The
purpose
this
study
was
to
ascertain
protective
impact
Juglans-regia-mediated
silver
nanoparticles
(AgNPs)
against
Aspergillus-ochraceus-induced
toxicity
exhibiting
strong
antifungal
activity
vitro
(wheat
seeds)
vivo
(Albino
rats)
settings.
For
synthesis
AgNPs,
leaf
extract
J.
regia
enriched
with
high
phenolic
(72.68
±
2.13
mg
GAE/g
DW)
flavonoid
(18.89
0.31
QE/g
contents
used.
Synthesized
AgNPs
were
characterized
techniques,
including
TEM,
EDX,
FT-IR,
XRD,
which
revealed
that
particles
spherical
shape
no
agglomeration
fine
particle
size
range
16-20
nm.
In
tested
wheat
grains
inhibiting
A.
ochraceus.
According
results
obtained
from
High-Performance
Liquid
Chromatography
(HPLC)
Thin-Layer
(TLC)
analyses,
there
correlation
between
concentration
decrease
aflatoxin
G1,
B1,
G2.
activity,
Albino
rats
administrated
different
doses
five
groups.
indicated
feed
50
µg/kg
more
effective
improving
disturbed
levels
functional
parameters
liver
(alanine
transaminase
(ALT):
54.0
3.79
U/L
aspartate
(AST):
206
8.69
U/L)
kidney
(creatinine
0.49
0.020
BUN
35.7
1.45
U/L),
as
well
lipid
profile
(LDL
22.3
HDL
26.3
2.33
U/L).
Furthermore,
histopathological
analysis
organs
successfully
inhibited
AgNPs.
It
concluded
harmful
effects
can
be
neutralized
using
regia-mediated
Notulae Scientia Biologicae,
Год журнала:
2024,
Номер
16(2), С. 11872 - 11872
Опубликована: Май 20, 2024
Neuroinflammation,
depletion
of
acetylcholine
and
neuronal
oxidative
stress
are
hallmarks
neurodegenerative
diseases
such
as
Alzheimer’s
disease.
This
study
sought
to
investigate
in
vitro
acetylcholinesterase
inhibitory
activity,
free
radical
scavenging,
antioxidant
anti-inflammatory
activity
aqueous
leaf
extract
Juglans
regia.
The
antioxidant,
anti-inflammatory,
acetylcholinesterase-inhibitory
activities
the
were
evaluated
using
different
appropriate
techniques.
showed
substantial
scavenging
by
markedly
hydroxyl
radical,
DPPH,
nitric
oxide,
hydrogen
peroxide,
with
concomitant
high
reducing
power.
Similarly,
lipid
peroxidation
inflammation
significantly
inhibited
extract.
elicited
potential
45.49%,
suggesting
they
could
be
beneficial
managing
diseases.
These
biological
can
attributed
phytochemical
constituents
Preliminary
screening
presence
polyphenols,
flavonoids,
tannins
GCMS
identified
phytochemicals
including
vanillic
acid,
p-Coumaric
caffeic
squalene.
concluded
that
J.
regia
exhibited
significant
which
mitigating
pathological
features
disease
other
diseases,
thus,
it
explored
health-promoting
dietary
supplements/
products.
Antioxidants,
Год журнала:
2024,
Номер
13(7), С. 811 - 811
Опубликована: Июль 4, 2024
α-Pinene
is
the
bicyclic,
unsaturated
terpene
hydrocarbon
present
in
many
plants.
Due
to
its
beneficial
chemical
properties,
this
compound
of
great
interest
and
has
found
numerous
applications
as
a
raw
material
industries
well
medicine
cosmetics.
The
aim
study
was
evaluate
antioxidant
activities
ethanolic
extracts
obtained
from
plants
containing
α-pinene
test
properties
cosmetic
emulsions
prepared
with
these
extracts.
plant
materials
consisted
fresh
parts
