Recent Advances in Micro- and Nano-Drug Delivery Systems Based on Natural and Synthetic Biomaterials

Polymers, Год журнала: 2023, Номер 15(23), С. 4563 - 4563

Опубликована: Ноя. 28, 2023

Polymeric drug delivery technology, which allows for medicinal ingredients to enter a cell more easily, has advanced considerably in recent decades. Innovative medication strategies use biodegradable and bio-reducible polymers, progress the field been accelerated by future possible research applications. Natural polymers utilized polymeric systems include arginine, chitosan, dextrin, polysaccharides, poly(glycolic acid), poly(lactic hyaluronic acid. Additionally, poly(2-hydroxyethyl methacrylate), poly(N-isopropyl acrylamide), poly(ethylenimine), dendritic bioabsorbable as well biomimetic bio-related drug-free macromolecular therapies have employed delivery. Different synthetic natural biomaterials are clinical phase mitigate different diseases. Drug methods using becoming increasingly common pharmaceutical industry, with biocompatible copolymers dendrimers having helped cure cancer systems. This review discusses all above components how, combining biological approaches, micro- nano-drug can result revolutionary gene devices.

Язык: Английский

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Static and ultrasonic structural health monitoring of full-size aerospace multi-function capsule using FBG strain arrays and PSFBG acoustic emission sensors

Optical Fiber Technology, Год журнала: 2023, Номер 78, С. 103316 - 103316

Опубликована: Март 31, 2023

Язык: Английский

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Characterization of optical fibers doped with nanoparticles for distributed displacement sensing

Optics Express, Год журнала: 2024, Номер 32(6), С. 9610 - 9610

Опубликована: Фев. 12, 2024

High-scattering optical fibers have emerged as a key component in distributed sensing systems, primarily due to their capacity enhance signal-to-noise ratio. This paper presents an experimental characterization of doped with oxide nanoparticles for displacement sensing. They were manufactured using the phase-separation technique and different doping compounds, including calcium, strontium, lanthanum magnesium. The Rayleigh backscattering (RBS) signatures time frequency domains acquired Optical Backscatter Reflectometer (OBR). maximum representative length, gain strain sensitivity evaluated. results indicate that fiber co-doped magnesium erbium chlorides offered best compromise between (0.96 pm/ μ ϵ ) length (17 m). For conditions single multiple perturbations, saturation was reached at ≥7000 m <1500 m, respectively. In addition, reveal that, under condition variable temperature (30-60 °C), sensor response becomes significantly nonlinear over requiring cross-sensitivity mitigation accounts nonlinearities hysteresis.

Язык: Английский

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Ultrasensitive RI and temperature sensor based on cascaded microfiber MZIs with Vernier effect

Optics & Laser Technology, Год журнала: 2024, Номер 177, С. 111082 - 111082

Опубликована: Апрель 30, 2024

Язык: Английский

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Forecast of solar cycle 25 based on Hybrid CNN-Bidirectional-GRU (CNN-BiGRU) model and Novel Gradient Residual Correction (GRC) technique

Advances in Space Research, Год журнала: 2024, Номер 73(8), С. 4342 - 4362

Опубликована: Янв. 11, 2024

Язык: Английский

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Optical performance evaluation of an infrared system of a hypersonic vehicle in an aero-thermal environment

Optics Express, Год журнала: 2023, Номер 31(16), С. 26517 - 26517

Опубликована: Июль 13, 2023

At hypersonic velocities, the turbulent flow field generated by an aircraft, along with its temperature distribution, leads to significant aerodynamic optical effects that severely impede performance of internal systems. This study proposes a method for analyzing temporal characteristics imaging degradation in detector window infrared system under different angles velocity. Based on heat transfer theory, solving transient high-speed aircraft is derived and established, considering unsteady thermal conduction-radiation coupling. Additionally, radiation tracing introduced, which directly determines initial direction vector light reaching detector. reduces workload transmission, significantly enhancing efficiency calculations. The time image caused aero-optical are analyzed using metrics such as peak signal-to-noise ratio, wave aberration, point diffusion function. results demonstrate working increases viewing angle widens, impact aero-optics becomes more severe. Moreover, compared transmission effect, effect has detrimental influence quality.

Язык: Английский

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Highly responsive reduced graphene oxide embedded PVDF flexible film-based room temperature operable humidity sensor

Sensors and Actuators A Physical, Год журнала: 2024, Номер 366, С. 115011 - 115011

Опубликована: Янв. 5, 2024

The current study reports a flexible, free-standing nanocomposite thick film based on reduced graphene oxide incorporated PVDF for room temperature humidity sensing application. A facile, cost-effective solvent casting method fabricates PVDF-RGO (PR) films with varied nanofiller loadings (0.1, 0.2, and 0.3 vol%). structural properties, including the variation in α, β, γ polymorphic phases, are studied detail from XRD, FTIR, Raman spectra, confirming β phase's dominance composite at lower RGO content. Optical studies confirm nanofiller-induced changes absorbance, bandgap, Urbach energy. For concentration (PR1 PR2), significant increase bandgap is observed compared to pure PVDF, trend reverses higher content (PR3), whereas energy has depicted an increasing filler Surface morphology roughness of analyzed using FESEM AFM images, respectively. Maximum surface PR3, which one reasons exceptional response latter sample. compositional analysis via XPS verified interaction between leading phase transformation. thermogram manifested increased thermal stability due inclusion as nano additive. measurements show that have exhibited excellent sensitivity relative range 11-97% PVDF. PR3 shown maximum 98.99% rapid dynamic recovery time 21 s 26 s, Hence, prepared revealed outstanding terms sensitivity, response/ time, long-term stability, negligible hysteresis.

Язык: Английский

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Unlocking the potential: Mining tailings as a source of sustainable nanomaterials

Renewable and Sustainable Energy Reviews, Год журнала: 2024, Номер 202, С. 114665 - 114665

Опубликована: Июнь 19, 2024

Язык: Английский

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Enhancing structural health monitoring of fiber-reinforced polymer composites using piezoresistive Ti3C2Tx MXene fibers

Scientific Reports, Год журнала: 2025, Номер 15(1)

Опубликована: Янв. 19, 2025

Abstract The anisotropic behavior of fiber-reinforced polymer composites, coupled with their susceptibility to various failure modes, poses challenges for structural health monitoring (SHM) during service life. To address this, non-destructive testing techniques have been employed, but they often suffer from drawbacks such as high costs and suboptimal resolutions. Moreover, routine inspections fail disclose incidents or failures occurring between successive assessments. As a result, there is growing emphasis on SHM methods that enable continuous without grounding the aircraft. Our research focuses advancing aerospace through utilization piezoresistive MXene fibers. MXene, characterized by its 2D nanofiber architecture exceptional properties, offers unique advantages strain sensing applications. We successfully fabricate fibers using wet spinning integrate them into carbon epoxy laminates in-situ sensing. Unlike previous studies focused levels, we adjust levels be comparable those encountered in practical results demonstrate remarkable sensitivity within low ranges, maximum 0.9 at 0.13% strain. Additionally, exhibited reliability repetitive tensile deformations low-velocity impact loading scenarios. This contributes development self-sensing offering enhanced capabilities early detection damage defects structures, thereby improving safety reducing maintenance expenses.

Язык: Английский

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Development and Validation of Full-Field Simulation Imaging Technology for Star Sensors under Hypersonic Aero-optical Effects

Optics Express, Год журнала: 2025, Номер 33(3), С. 6526 - 6526

Опубликована: Янв. 21, 2025

Hypersonic vehicles equipped with star sensors operating in near-space environments experience aero-optical effects caused by the surrounding high-temperature and high-pressure flow fields. These significantly degrade sensor’s imaging capability, damage image quality, lead to failures attitude determination calculations. To investigate impact of on detection performance hypersonic platforms, this paper first proposes a simulation technique for full-field sensor analyzes capability visible spectrum under flight conditions ranging from 6 16 Ma. Next, address challenging conditions, discusses optimization strategies enhancing sensor, considering factors such as wavelength band, installation configuration, optical system design. Finally, validate reliability paper, detonation-driven shock tunnel experiment observation is designed, comparative analysis experimental results conducted perspectives light transmission thermal radiation effects. The demonstrate that proposed can accurately predict errors controlled within 30%.

Язык: Английский

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