Research Square (Research Square),
Год журнала:
2024,
Номер
unknown
Опубликована: Июль 1, 2024
Intermittent
fasting
(IF)
focuses
on
the
timing
of
eating
rather
than
diet
quality
or
energy
intake,
with
evidence
supporting
its
effects
weight
loss
and
cardiometabolic
outcomes
in
adults.
However,
there
is
limited
for
efficacy
adolescents
emerging
To
address
this,
a
scoping
review
examined
IF
regimens
individuals
aged
10
to
25,
focusing
methodology,
intervention
parameters,
outcomes,
adherence,
feasibility,
efficacy.
The
included
39
studies
731
participants
15
25.
Methodologies
varied,
18
time-restricted
others
requiring
caloric
restriction.
Primary
risk
factors
(11/29),
body
composition
(9/29),
anthropometric
measurements
(8/29),
feasibility
(2/29).
Most
reported
significant
loss.
This
underscores
IF's
potential
treating
obesity
this
age
group
but
highlights
need
rigorous
standardized
frameworks
ensure
comparability
determine
practicality
group.
Foods,
Год журнала:
2024,
Номер
13(13), С. 1960 - 1960
Опубликована: Июнь 21, 2024
Intermittent
fasting
(IF)
has
been
indicated
as
a
valuable
alternative
to
the
classical
caloric
restriction
dietary
regimen
for
lowering
body
weight
and
preventing
obesity-related
complications,
such
metabolic
syndrome
type
II
diabetes.
However,
is
it
effective?
In
this
review
article,
we
analyzed
over
50
clinical
studies
in
which
IF,
conducted
by
alternate
day
(ADF)
or
time-restricted
feeding
(TRF),
was
compared
with
approach.
We
evaluated
different
roles
of
IF
treating
human
disorders
syndrome,
diabetes,
some
types
cancer,
well
usefulness
reducing
cardiovascular
risk
factors
hypertension.
Furthermore,
explored
cellular
pathways
targeted
exert
their
beneficial
effects
activating
effector
proteins
that
modulate
cell
functions
resistance
oxidative
stress.
contrast,
investigated
concerns
regarding
health
related
adoption
regimens,
highlighting
profound
debate
surrounding
loss
regimens.
examined
several
trials
formulate
an
updated
concept
its
therapeutic
potential.
Frontiers in Nutrition,
Год журнала:
2025,
Номер
12
Опубликована: Янв. 17, 2025
Intermittent
fasting
has
been
linked
to
metabolic
health
by
improving
lipid
profiles,
reducing
body
weight,
and
increasing
insulin
sensitivity.
However,
several
randomized
clinical
trials
have
shown
that
intermittent
is
not
more
effective
than
standard
daily
caloric
restriction
for
short-term
weight
loss
or
cardiometabolic
improvements
in
patients
with
obesity.
Observational
studies
also
suggest
cardiovascular
benefits
from
extended
rather
reduced
eating
windows,
indicate
long-term
regimens
may
increase
the
risk
of
disease
mortality.
In
this
perspective,
we
discuss
evidence
support
potential
adverse
effects
on
through
lean
mass,
circadian
misalignment
poor
dietary
choices
associated
reward-based
eating.
Given
ongoing
revolution
obesity
pharmacotherapy,
argue
future
research
should
integrate
anti-obesity
medications
strategies
confer
robust
health,
combine
exercise
regimens,
consider
genetic
factors
personalize
treatment.
Comprehensive
approaches
combining
diet,
lifestyle
modifications
will
become
crucial
managing
minimizing
risk.
Biology,
Год журнала:
2025,
Номер
14(2), С. 158 - 158
Опубликована: Фев. 4, 2025
Epilepsy,
a
brain
condition
causing
recurrent
seizures,
can
disrupt
various
body
functions,
including
urination.
This
study
explored
how
alternate-day
fasting
(ADF),
type
of
intermittent
fasting,
diet
involving
one
day
eating
and
subsequently
affects
urinary
system
health
in
epileptic
rats.
Using
genetic
rat
model
epilepsy,
we
examined
bladder
kidney
function
through
tissue
analysis,
biochemical
tests,
physiological
assessments,
focusing
on
differences
between
males
females.
The
results
showed
that
epilepsy
causes
significant
damage
linked
to
inflammation
oxidative
stress.
However,
ADF
reduces
this
by
lowering
restoring
antioxidant
balance.
Male
rats
exhibited
more
damage,
while
female
responded
better
ADF,
likely
due
hormonal
differences.
These
findings
suggest
as
potential,
cost-effective
dietary
approach
protect
against
complications
similar
conditions.
Understanding
these
effects
may
lead
improved
treatments
for
both
genders
quality
life
people
with
chronic
diseases.
Frontiers in Neuroendocrinology,
Год журнала:
2025,
Номер
unknown, С. 101189 - 101189
Опубликована: Апрель 1, 2025
Alzheimer's
disease
(AD)
disproportionately
affects
women,
with
postmenopausal
hormonal
changes
contributing
to
elevated
risk.
Physical
exercise
is
a
promising,
non-pharmacological
strategy
mitigate
cognitive
decline
and
AD
progression.
Brain-derived
neurotrophic
factor
(BDNF)
irisin
are
key
molecular
mediators
of
exercise-induced
brain
health
protection
against
pathology
by
promoting
synaptic
plasticity,
neurogenesis,
reducing
amyloidosis,
tau
pathology,
neuroinflammation
in
sex-specific
mechanisms.
This
review
explores
sex
gender
influences
on
outcomes
their
interaction
FNDC5/irisin
BDNF
signaling
pathways
the
context
prevention.
We
highlight
emerging
evidence
interplay
between
exercise,
sex,
neuroprotective
pathways,
emphasizing
need
for
sex-sensitive
research
designs
advance
precision
approaches
journal of nutritional oncology,
Год журнала:
2025,
Номер
unknown
Опубликована: Апрель 11, 2025
Intermittent
fasting
(IF)
has
emerged
as
a
potential
adjunctive
strategy
in
cancer
prevention,
mitigation,
and
treatment.
This
narrative
review
synthesizes
existing
literature
to
explore
the
relationship
between
IF
across
3
dimensions:
We
examine
underlying
mechanisms
by
which
may
reduce
risk,
including
its
effects
on
insulin-like
growth
factor
1
suppression,
autophagy
induction,
chronic
inflammation
reduction.
Furthermore,
we
discuss
IF’s
enhance
efficacy
of
conventional
therapies
sensitizing
cells,
promoting
apoptosis,
reducing
treatment-related
side
effects.
While
promising,
evidence
is
still
limited,
further
research
required
elucidate
long-term
impact
optimal
implementation
care.
aims
provide
health
care
professionals
patients
with
comprehensive
understanding
benefits
risks
associated
complementary
approach
oncology
setting.
Background:
Cognitive
dysfunction
is
a
significant
health
challenge
in
the
global
elderly
population,
and
its
prevalence
associated
with
multiple
factors,
including
modifiable
lifestyle
factors.
The
relationship
between
nighttime
fasting
duration,
potential
factor,
cognitive
function
has
yet
to
be
thoroughly
investigated.
Objective:
To
investigate
association
duration
function.
Methods:
This
cross-sectional
study
was
based
on
data
from
National
Health
Nutrition
Examination
Survey
(NHANES)
2011
2014.
Weighted
linear
regression
utilized
examine
function,
additional
curve
fitting
inflection
point
analysis
conducted
further
elucidate
this
Results:
There
negative
(Learn:
β
=
-1.2,
95%
CI:
-1.98,
-0.43,
P
0.006;
Recall:
-1.1,
-2.11,
-0.09,
0.036;
Animal
Fluency:
-4.49,
-7.26,
-1.72,
0.004;
Digit
Symbol
Substitution
Test:
-12.66,
-19.30,
-6.01,
0.002).
Subgroup
analyses
showed
that
correlation
prevalent
most
subgroups.
Curve
revealed
scores,
but
did
not
identify
point.
Conclusions:
Longer
times
may
decline,
either
as
continuous
or
categorical
variable.
npj Metabolic Health and Disease,
Год журнала:
2024,
Номер
2(1)
Опубликована: Дек. 30, 2024
Intermittent
fasting
focuses
on
the
timing
of
eating
rather
than
diet
quality
or
energy
intake,
with
evidence
supporting
its
effects
weight
loss
and
improvements
in
cardiometabolic
outcomes
adults
obesity.
However,
there
is
limited
for
feasibility
efficacy
young
people.
To
address
this,
a
scoping
review
was
conducted
to
examine
intermittent
regimens
individuals
aged
10
25
treatment
obesity
focusing
methodology,
intervention
parameters,
outcomes,
adherence,
feasibility,
efficacy.
Due
paucity
this
age
group,
adequately
assess
all
published
studies
category,
regardless
status
intention,
were
included
review.
The
34
(28
interventional
6
observational
studies)
893
participants
12
25.
Interventions
varied
9
cohorts
utilizing
as
an
treatment.
Thirteen
utilized
8-h
time-restricted
eating.
Primary
risk
factors
(7/28),
anthropometric
measurements
body
composition
(5/28),
muscular
performance
(4/28),
(1/28),
others
(4/28).
All
people
reported
some
degree
loss,
although
comparator
groups
significantly.
This
underscores
various
utilizations
group
highlights
potential
treating
findings
emphasize
need
rigorous
standardized
frameworks
ensure
comparability
determine
fasting's
practicality
depending
outcome
interest.
Jurnal Ilmu Keolahragaan,
Год журнала:
2024,
Номер
7(1), С. 50 - 50
Опубликована: Май 30, 2024
Peningkatan
pengeluaran
energi
expeditur
dengan
olahraga
dan
kombinasi
puasa
diyakini
dapat
memaksimalkan
kalori
meningkatkan
kadar
BDNF,
oleh
karena
itu
penelitian
ini
bertujuan
untuk
membuktikan
perubahan
profil
BDNF
wanita
obesitas
yang
disebabkan
puasa.
Penelitian
melibatkan
16
perempuan
sebagai
subyek
penelitian,
kemudian,
subjek
dibagi
menjadi
2
kelompok
:
kontrol
(K1;
n
=
8)
(K2;
8).
Olahraga
aerobik
menggunakan
treadmill
selama
40
menit,
intensitas
sedang,
sedangkan
dilakukan
intermittent
jam,
dilanjutkan
tidak
berpuasa
8
jam.
Kombinasi
minggu.
Pengambilan
sampel
darah
mengukur
diambil
dari
vena
cubiti
sebanyak
4
mL,
sebelum
setelah
perlakuan.
Analisis
data
mengunakan
paired
sample
t
test
tingkat
signifikan
5%.
Berdasarkan
hasil
terdapat
perbedaan
signifikan.
antara
perlakuan
(p
≤
0,05).
Hasil
tersebut
menunjukkan
menghambat
laju
masuk
pada
obesitas.
program
disarankan
pengurangan
massa
lemak
akibat
berpengaruh
terhadap
metabolisme
Nutritional Neuroscience,
Год журнала:
2024,
Номер
unknown, С. 1 - 15
Опубликована: Июль 2, 2024
Alzheimer's
disease
(AD)
is
a
progressive
neurodegenerative
disorder
affecting
approximately
55
million
individuals
globally.
Diagnosis
typically
occurs
in
advanced
stages,
and
there
are
limited
options
for
reversing
symptoms.
Preventive
strategies
are,
therefore,
crucial.
Time
Restricted
Eating
(TRE)
or
Feeding
(TRF)
one
such
strategy.
Here
we
review
recent
research
on
AD
TRE/TRF
addition
to
biomarkers
gut
microbiota.
Molecules,
Год журнала:
2024,
Номер
29(23), С. 5723 - 5723
Опубликована: Дек. 4, 2024
L.
has
been
traditionally
applied
as
a
remedy
for
headaches,
rheumatism,
digestion,
respiratory
and
neurological
problems,
other
medical
conditions.
However,
the
literature
data
on
its
effects
cognitive
function
are
scarce.
The
aim
of
present
work
was
to
evaluate
two
doses
