Enhanced RBD-Specific Antibody Responses and SARS-CoV-2-Relevant T-Cell Activity in Healthcare Workers Following Booster Vaccination DOI Creative Commons
Lina Souan, Hikmat Abdel‐Razeq, Maher A. Sughayer

и другие.

Current Issues in Molecular Biology, Год журнала: 2024, Номер 46(10), С. 11124 - 11135

Опубликована: Окт. 2, 2024

COVID-19 continues to impact healthcare workers (HCWs), making it crucial investigate vaccine response rates. This study examined HCWs’ humoral and cellular immunological responses booster dosages. We enrolled thirty-four vaccinated HCWs. Twelve received a booster. Post-immunization, the participants’ anti-COVID-19 IgG antibodies IFN-γ secretion were assessed. The median second immunization time was 406.5 days. Eighteen of twenty-two (81.8%) experienced breakthrough infections after vaccination, whereas ten out twelve individuals who doses had (83.3%). Six HCWs (17.6%) no infections. Booster-injection recipients antibody titer 19,592 AU/mL, compared 7513.55 AU/mL. with exhibited 13,271.9 7770.65 AU/mL for those without Breakthrough-infection booster-injection groups slightly higher T-cell antigens 1, 2, 3. SARS-CoV-2 responsiveness positively associated. sustain immunity over 10 months. Irrespective type vaccine, injections enhance these immune responses. results our research are consistent previous studies, multicenter investigation could validate findings.

Язык: Английский

Impact on Human Health, Lifestyle, and Quality of Care After COVID-19 DOI Creative Commons
Bogdana Adriana Năsui, Codruța Alina Popescu

Medicina, Год журнала: 2025, Номер 61(4), С. 630 - 630

Опубликована: Март 29, 2025

The COVID-19 pandemic has been an unprecedented global event in recent times, disrupting lives, economies, and healthcare systems worldwide [...]

Язык: Английский

Процитировано

0
Enhanced RBD-Specific Antibody Responses and SARS-CoV-2-Relevant T-Cell Activity in Healthcare Workers Following Booster Vaccination DOI Creative Commons
Lina Souan, Hikmat Abdel‐Razeq, Maher A. Sughayer

и другие.

Current Issues in Molecular Biology, Год журнала: 2024, Номер 46(10), С. 11124 - 11135

Опубликована: Окт. 2, 2024

COVID-19 continues to impact healthcare workers (HCWs), making it crucial investigate vaccine response rates. This study examined HCWs’ humoral and cellular immunological responses booster dosages. We enrolled thirty-four vaccinated HCWs. Twelve received a booster. Post-immunization, the participants’ anti-COVID-19 IgG antibodies IFN-γ secretion were assessed. The median second immunization time was 406.5 days. Eighteen of twenty-two (81.8%) experienced breakthrough infections after vaccination, whereas ten out twelve individuals who doses had (83.3%). Six HCWs (17.6%) no infections. Booster-injection recipients antibody titer 19,592 AU/mL, compared 7513.55 AU/mL. with exhibited 13,271.9 7770.65 AU/mL for those without Breakthrough-infection booster-injection groups slightly higher T-cell antigens 1, 2, 3. SARS-CoV-2 responsiveness positively associated. sustain immunity over 10 months. Irrespective type vaccine, injections enhance these immune responses. results our research are consistent previous studies, multicenter investigation could validate findings.

Язык: Английский

Процитировано

0