F1000Research,
Год журнала:
2024,
Номер
13, С. 1366 - 1366
Опубликована: Ноя. 14, 2024
Background
Atopic
dermatitis
(AD)
is
a
chronic
inflammatory
skin
condition
characterized
by
pruritus
and
barrier
dysfunction.
This
study
aims
to
evaluate
the
therapeutic
potential
of
Pelargonium
graveolens
(Geraniaceae)
in
managing
AD
symptoms
through
its
essential
oil.
Methods
The
chemical
composition
flower
oil
(PFEO)
was
analyzed
using
gas
chromatography-mass
spectrometry
(GC-MS).
Its
antimicrobial,
antioxidant,
anti-inflammatory
properties
were
assessed,
along
with
inhibitory
effects
PFEO
on
key
enzymes
involved
repair:
tyrosinase,
elastase,
collagenase.
An
vivo
evaluation
gel
formulation
containing
also
conducted
assess
analgesic
efficacy.
Results
GC-MS
analysis
identified
major
compounds
PFEO,
including
Geraniol
(22.83%),
beta-citronellol
(19.51%),
naphthalenemethanol
(15.36%),
Geranyl
tiglate
(9.38%),
minor
constituents
such
as
linalool
(3.81%)
neryl
formate
(1.31%).
exhibited
bacteriostatic
activity
against
various
bacterial
fungal
strains,
Pseudomonas
aeruginosa,
Staphylococcus
aureus,
Methicillin-Resistant
aureus
(MRSA),
Bacillus
anthracis,
Streptococcus
pyogenes,
epidermidis,
Candida
albicans,
Malassezia
spp.
demonstrated
significant
antioxidant
inhibited
linked
alterations
AD.
Conclusions
shows
promising
for
atopic
due
properties,
well
effects.
findings
support
further
exploration
natural
alternative
treatment
AD.
Processes,
Год журнала:
2023,
Номер
11(9), С. 2757 - 2757
Опубликована: Сен. 15, 2023
The
primary
objective
of
this
study
was
to
investigate
the
survival
rate
three
species
encapsulated
bacteria
(Propionibacterium
acidipropionicici,
Propionibacterium
freudenreichii,
and
thoenii)
in
model
solutions
designed
simulate
acidity
levels
found
within
human
gastrointestinal
tract.
capsules
were
prepared
by
extrusion
from
gelatin
sodium
alginate
a
1:1
ratio
on
laboratory
encapsulator.
use
provide
optimum
characteristics
suitable
for
encapsulation
live
bacteria.
Three
strains
asidirgorionici,
thoenii
subjected
vitro
assay
evaluate
their
probiotic
potential.
final
cell
P.
freudenreichii
105
CFU/mL,
indicating
that
is
sensitive
acidic
medium.
viability
probiotics
studied
medium
simulating
It
alginate–gelatin
could
protection
gastric
acid
lead
high
viable
released
intestine.
Practical
application:
Encapsulation
into
produced
capable
delivering
Applied Sciences,
Год журнала:
2024,
Номер
14(13), С. 5557 - 5557
Опубликована: Июнь 26, 2024
The
increase
in
the
nutritional
awareness
of
consumers
has
meant
that
products
with
high
value,
sensory
attractiveness,
and
safety
are
currently
being
sought
on
market.
One
aspects
which
innovativeness
a
food
product
can
be
considered
is
preservation
method.
Fermentation
one
oldest
methods.
In
practice,
biopreservation
primarily
method
using
non-pathogenic
microorganisms
and/or
their
metabolites
to
microbiological
extend
shelf
life.
Advances
microbiology
genetic
engineering,
taking
into
account
various
sources
microbiota
isolation,
have
rediscovered
fermentation
process
allowed
us
obtain
innovative
functional
products.
Recently,
bacteriocins
gained
importance.
For
many
years,
they
been
applied
as
biopreservatives
manufacturing,
alone
or
combination
other
preservatives.
most
promising
perspective
seems
development
combined
systems
including
natural
preservatives
(i.e.,
bacteriocin
lipopeptides),
emerging
non-thermal
technologies,
methods
such
encapsulation
nanotechnology
active
packaging.
this
paper,
narrative
review
presented
analyze
recently
published
literature
regarding
role
microbial
produced
antibacterial
compounds
biopreservation.
New
technologies
an
alternative
artificial
were
also
discussed.
Future Integrative Medicine,
Год журнала:
2024,
Номер
3(1), С. 21 - 34
Опубликована: Март 25, 2024
Coptis
teeta
Wall.
(C.
teeta)
is
a
herb
that
goes
by
the
name
"Mishmi
Tita",
and
holds
significant
value
as
medicinal
plant
for
treating
various
health
conditions.
This
endangered
plant,
listed
in
Red
Data
Book,
commonly
found
India,
Nepal,
Bhutan
China.
The
present
review
aims
to
comprehensively
summarize
traditional,
pharmaceutical,
phytochemical
aspects
of
C.
teeta,
providing
foundation
researchers
explore
this
take
bold
steps
conserve,
cultivate,
promote
awareness
among
local
people.
A
thorough
literature
search
was
conducted
on
PubMed,
Google
Scholar,
Research
Gate,
SciFinder,
ISI
Web
Knowledge,
using
following
terms:
"Coptis
teeta",
Wall.",
tita",
"Rhizoma
coptidis",
"Chinese
medicine
from
"Traditional
uses
teeta".
comprehensive
examination
69
articles
published
between
1982
2023
properties
traditional
applications
teeta.
It
its
active
compounds
exhibit
range
effects,
such
fighting
against
microbes,
alleviating
diarrhoea,
lowering
blood
pressure,
regulating
heart
rhythm,
reducing
inflammation,
improving
mood,
trachoma,
managing
diabetes,
pain
relief,
countering
reactions.
total
27
were
identified
different
parts
according
surveyed
literature.
These
have
been
traditionally
utilized
address
ailments,
including
conditions,
eye
disorders,
skin
issues,
gastrointestinal
troubles
like
constipation
jaundice,
urinary
disorders.
Furthermore,
these
shown
potential
cancer
treatment
mitigating
inflammation.
boasts
diverse
promising
pharmacological
activities
due
rich
chemical
composition.
Berberine
main
constituent,
communities
utilize
it
ailments.
While
endangered,
offers
exciting
potential,
warranting
further
research
sustainable
conservation
efforts.
Cultivating
raising
public
are
crucial
towards
preservation.
Pathogens,
Год журнала:
2024,
Номер
13(12), С. 1123 - 1123
Опубликована: Дек. 19, 2024
The
prevalence
of
antimicrobial-resistant
bacteria
in
meat
and
products
is
a
significant
public
health
challenge,
largely
driven
by
the
excessive
inappropriate
use
antimicrobials
animal
husbandry.
In
Poland,
key
producer
Europe,
antibiotic-resistant
pathogens
such
as
Campylobacter
spp.,
Staphylococcus
Enterococcus
Listeria
monocytogenes,
Enterobacterales
have
been
detected
meat,
posing
serious
risks
to
consumers.
This
review
examines
antimicrobial
agents
production
resulting
resistance
(AMR)
microorganisms
isolated
from
Poland.
mechanisms
AMR,
genetic
factors,
Poland
are
presented.
It
highlights
factors
contributing
antibiotic
misuse
livestock
farming,
discusses
legal
regulations
governing
veterinary
drug
residues
food.
emphasizes
importance
monitoring
enforcement
safeguard
calls
for
further
research
on
AMR
industry.
Antimicrobial
huge
requiring
stricter
controls
husbandry
improved
surveillance
systems.
Additionally,
impact
practices
environment
food
requires
research.
Future
efforts
should
focus
nationwide
monitoring,
alternative
strategies
reduce
use,
stronger
combat
protect
health.
Frontiers in Microbiology,
Год журнала:
2024,
Номер
15
Опубликована: Сен. 9, 2024
Probiotics
and
their
derivatives
offer
significant
health
benefits
by
supporting
digestive
health,
boosting
the
immune
system,
regulating
microbiomes
not
only
of
internal
gastrointestinal
track
but
also
skin.
To
be
effective,
probiotics
must
exhibit
robust
antimicrobial
activity,
resilience
to
adverse
conditions,
colonization
capabilities
in
host
tissues.
As
an
alternative
animal-derived
probiotics,
plant-derived
lactic
acid
bacteria
(LAB)
present
promising
advantages,
including
enhanced
diversity
tolerance
challenging
environments.
Our
study
focuses
on
exploring
potential
LAB,
particularly
from
medicinal
plant
Centella
asiatica
,
improving
skin
conditions.
Through
a
bacterial
isolation
procedure
C.
leaves,
Enterococcus
rotai
CMTB-CA6
was
identified
via
16S
rRNA
sequencing,
whole
genome
bioinformatic
analyses.
Based
genomic
analysis,
antimicrobial-resistance
virulence
genes
were
detected.
Additionally,
functions
E.
characterized
its
lysates’
ability
regulate
microbes,
such
as
stimulating
growth
Staphylococcus
epidermidis
while
inhibiting
that
Cutibacterium
acnes
restore
viability
human
dermal
fibroblasts
under
inflammatory
demonstrate
effective
antioxidant
activities
both
cell-free
system
fibroblasts.
investigation
revealed
efficacy
lysates
suggesting
use
probiotic-derived
agent
for
care
products.
Considering
ecological
relationship
between
plant-inhabited
plants,
we
suggest
utilization
strain
fermenting
plant,
could
novel
approach
efficiently
enriching
bioactive
molecules
benefits.
The
body's
normal
microflora
is
disrupted
by
antibiotics,
which
do
not
distinguish
between
good
and
harmful
bacteria.
This
results
in
vitamin
deficiencies.
They
undermine
the
host's
defenses
reducing
population
of
helpful
bacteria
gastrointestinal
system
vaginal
area.
Due
to
beneficial
effects
they
have
on
human
wellness,
including
immune
metabolism,
probiotics
are
considered
be
an
"organ"
metabolic
system.
From
a
therapeutic
standpoint,
these
substances
employed
for
purpose
both
prevention
treatment
across
diverse
range
medical
conditions.
Diarrhea,
colorectal
cancer,
diabetes,
hypertension,
Helicobacter
pylori
-related
acute
pancreatitis,
ventilator-associated
pneumonia,
migraine
headaches,
autistic
spectrum
disorder
all
examples
such
issues.
Probiotics
can
influence
immunological
activity
number
ways.
These
include
triggering
adaptive
or
innate
responses,
changing
gut
bacterial
composition,
increasing
barrier
integrity,
attaching
competitively
mucosa
epithelium,
generating
antimicrobial
chemicals.
finding
emphasizes
need
more
probiotic
research
cure
prevent
illnesses.
Searches
databases
employing
probiotics,
microbiota,
prophylactics,
purposes
were
extensive.
brief
narrative
chapter
covers
probiotics'
background,
selection,
effects,
newest
preventive
findings,
potential
uses.
F1000Research,
Год журнала:
2024,
Номер
13, С. 1366 - 1366
Опубликована: Ноя. 14, 2024
Background
Atopic
dermatitis
(AD)
is
a
chronic
inflammatory
skin
condition
characterized
by
pruritus
and
barrier
dysfunction.
This
study
aims
to
evaluate
the
therapeutic
potential
of
Pelargonium
graveolens
(Geraniaceae)
in
managing
AD
symptoms
through
its
essential
oil.
Methods
The
chemical
composition
flower
oil
(PFEO)
was
analyzed
using
gas
chromatography-mass
spectrometry
(GC-MS).
Its
antimicrobial,
antioxidant,
anti-inflammatory
properties
were
assessed,
along
with
inhibitory
effects
PFEO
on
key
enzymes
involved
repair:
tyrosinase,
elastase,
collagenase.
An
vivo
evaluation
gel
formulation
containing
also
conducted
assess
analgesic
efficacy.
Results
GC-MS
analysis
identified
major
compounds
PFEO,
including
Geraniol
(22.83%),
beta-citronellol
(19.51%),
naphthalenemethanol
(15.36%),
Geranyl
tiglate
(9.38%),
minor
constituents
such
as
linalool
(3.81%)
neryl
formate
(1.31%).
exhibited
bacteriostatic
activity
against
various
bacterial
fungal
strains,
Pseudomonas
aeruginosa,
Staphylococcus
aureus,
Methicillin-Resistant
aureus
(MRSA),
Bacillus
anthracis,
Streptococcus
pyogenes,
epidermidis,
Candida
albicans,
Malassezia
spp.
demonstrated
significant
antioxidant
inhibited
linked
alterations
AD.
Conclusions
shows
promising
for
atopic
due
properties,
well
effects.
findings
support
further
exploration
natural
alternative
treatment
AD.
