Applied Sciences,
Год журнала:
2024,
Номер
14(4), С. 1589 - 1589
Опубликована: Фев. 16, 2024
The
co-occurrence
of
aflatoxin
B1
(AFB1)
and
zearalenone
(ZEN)
in
grain-based
food
animal
feed
poses
significant
health
risks
to
humans
animals
due
their
potent
mutagenic,
cytotoxic,
carcinogenic
properties.
Conventional
physical
chemical
methods
are
insufficient
for
effectively
detoxifying
multiple
mycotoxins
present
feed.
In
this
study,
we
evaluated
the
capability
Bacillus
subtilis
ZJ-2019-1
(B.
ZJ-2019-1)
simultaneously
degrade
AFB1
ZEN
while
optimizing
reaction
enhance
degradation
efficiency.
localization
active
ingredients
from
B.
was
determined
using
high-performance
liquid
chromatography
(HPLC).
Our
findings
demonstrated
that
eliminated
60.88%
33.18%
within
72
h
at
a
concentration
10
mg/L
37
°C
(pH
7.0)
exerted
greater
activity
under
alkaline
conditions.
autoclaved
boiled
supernatants
exhibited
enhancement
ZEN,
achieving
rates
79.85%
100%,
respectively,
1
48
°C.
Moreover,
crude
enzymes
showed
maximum
(100%)
(94.29%)
70
Additionally,
divalent
cations
(such
as
Co2+,
Fe2+,
Mn2+,
Ni2+)
significantly
augmented
towards
mycotoxin
degradation.
Furthermore,
when
applied
corn
gluten
meals,
strain
detoxify
66.08%
22.01%
surpassing
efficacy
commercial
detoxification
agent
on
market
(34.17%
2.28%
ZEN).
Collectively,
these
indicated
is
promising
candidate
simultaneous
removal
feed,
addressing
concerns
associated
with
harmful
mycotoxins.
Cells,
Год журнала:
2023,
Номер
12(1), С. 184 - 184
Опубликована: Янв. 2, 2023
Immune
cells
and
commensal
microbes
in
the
human
intestine
constantly
communicate
with
react
to
each
other
a
stable
environment
order
maintain
healthy
immune
activities.
system-microbiota
cross-talk
relies
on
complex
network
of
pathways
that
sustain
balance
between
tolerance
immunogenicity.
Probiotic
bacteria
can
interact
stimulate
intestinal
microflora
modulate
specific
functions
homeostasis.
Growing
evidence
shows
probiotic
present
important
health-promoting
immunomodulatory
properties.
Thus,
use
probiotics
might
represent
promising
approach
for
improving
system
So
far,
few
studies
have
been
reported
beneficial
modulatory
effect
probiotics.
However,
many
others,
which
are
mainly
focused
their
metabolic/nutritional
properties,
published.
Therefore,
mechanisms
behind
interaction
host
only
partially
described.
The
review
aims
collect
summarize
most
recent
scientific
results
resulting
implications
how
improve
functions.
Hence,
description
currently
known
is
provided.
Frontiers in Nutrition,
Год журнала:
2022,
Номер
9
Опубликована: Окт. 5, 2022
Prebiotics
and
probiotics
play
a
positive
role
in
promoting
human
nutrition
health.
are
compounds
that
cannot
be
digested
by
the
host,
but
can
used
fermented
probiotics,
so
as
to
promote
reproduction
metabolism
of
intestinal
for
health
body.
It
has
been
confirmed
have
clinical
or
care
functions
preventing
controlling
intestinal,
respiratory,
urogenital
infections,
allergic
reaction,
inflammatory
bowel
disease,
irritable
syndrome
other
aspects.
However,
there
few
systematic
summaries
these
types,
mechanisms
action
promotion
relationship
between
prebiotics
probiotic.
Therefore,
we
summarized
various
types
their
individual
mechanisms,
mechanism
tract.
is
hoped
this
review
provide
new
ideas
application
future.
Biomedicine & Pharmacotherapy,
Год журнала:
2022,
Номер
155, С. 113810 - 113810
Опубликована: Окт. 8, 2022
The
human
gut
microbiota
is
a
complex
ecosystem
involved
in
the
metabolism,
immunity,
and
health
of
host.
microbiome
plays
key
role
development
host's
innate
adaptive
immune
system,
while
system
orchestrates
maintenance
host-microbe
symbiosis.
Lung
diseases
are
usually
accompanied
by
dysbiosis
intestinal
flora
an
immune-inflammatory
response.
its
metabolites
directly
or
indirectly
regulation
host
lung
disease.
However,
exact
mechanism
action
gut-lung
axis
crosstalk
remains
unclear.
This
review
aimed
to
summarize
latest
advances
their
typical
diseases,
such
as
pulmonary
hypertension,
COPD,
cancer.
Especially
COVID-19,
problem
troubling
world,
also
discussed
it.
Moreover,
it
concentrated
on
mechanisms
between
identified
specific
link
among
microbiota,
metabolites,
regulation,
which
could
be
used
breakthrough
find
new
targets
for
some
without
therapeutic
drugs
clinic.
It
tool
"drug-bacterial
interaction"
potential
applications
would
provide
clear
direction
future
research
propose
strategy
targeting
Frontiers in Microbiology,
Год журнала:
2024,
Номер
14
Опубликована: Янв. 5, 2024
The
imbalance
of
microbial
composition
and
diversity
in
favor
pathogenic
microorganisms
combined
with
a
loss
beneficial
gut
microbiota
taxa
results
from
factors
such
as
age,
diet,
antimicrobial
administration
for
different
infections,
other
underlying
medical
conditions,
etc.
Probiotics
are
known
their
capacity
to
improve
health
by
stimulating
the
indigenous
microbiota,
enhancing
host
immunity
resistance
infection,
helping
digestion,
carrying
out
various
functions.
Concurrently,
metabolites
produced
these
microorganisms,
termed
postbiotics,
which
include
compounds
like
bacteriocins,
lactic
acid,
hydrogen
peroxide,
contribute
inhibiting
wide
range
bacteria.
This
review
presents
an
update
on
using
probiotics
managing
treating
human
diseases,
including
complications
that
may
emerge
during
or
after
COVID-19
infection.
Foods,
Год журнала:
2024,
Номер
13(1), С. 151 - 151
Опубликована: Янв. 2, 2024
Functional
dyspepsia
(FD)
is
a
common
functional
gastrointestinal
disorder.
The
pathophysiology
remains
poorly
understood;
however,
alterations
in
the
small
intestinal
microbiome
have
been
observed.
Current
treatments
for
FD
with
drugs
are
limited,
and
there
certain
safety
problems.
A
class
of
active
probiotic
bacteria
can
control
homeostasis,
nutritional
digestion
absorption,
energy
balance
when
taken
dosages.
Probiotics
play
many
roles
maintaining
microecological
balance,
improving
barrier
function,
regulating
immune
response.
presence
composition
microorganisms
vital
role
onset
progression
serve
as
critical
factor
both
regulation
potential
intervention
regarding
management
this
condition.
Thus,
advantages
to
alleviating
by
flora
using
probiotics,
targeting
microorganisms.
This
review
summarizes
research
progress
probiotics
provides
reference
basis
improve
FD.
Nutrients,
Год журнала:
2024,
Номер
16(6), С. 789 - 789
Опубликована: Март 10, 2024
Recent
research
exploring
the
relationship
between
gut
and
brain
suggests
that
condition
of
microbiota
can
influence
cognitive
health.
A
well-balanced
may
help
reduce
inflammation,
which
is
linked
to
neurodegenerative
conditions.
Prebiotics,
probiotics,
symbiotics
are
nutritional
supplements
functional
food
components
associated
with
gastrointestinal
well-being.
The
bidirectional
communication
gut–brain
axis
essential
for
maintaining
homeostasis,
pre-,
pro-,
potentially
affecting
various
functions
such
as
attention,
perception,
memory.
Numerous
studies
have
consistently
shown
incorporating
into
a
healthy
diet
lead
improvements
in
mood.
Maintaining
support
optimal
function,
crucial
disease
prevention
our
fast-paced,
Westernized
society.
Our
results
indicate
benefits
older
individuals
probiotic
supplementation
but
not
who
good
adequate
levels
physical
activity.
Additionally,
it
appears
there
patients
mild
impairment
Alzheimer’s
disease,
while
mixed
seem
arise
younger
healthier
individuals.
However,
important
acknowledge
individual
responses
vary,
use
these
dietary
should
be
tailored
each
individual’s
unique
health
circumstances
needs.
Biological Control,
Год журнала:
2024,
Номер
188, С. 105439 - 105439
Опубликована: Янв. 1, 2024
Beneficial
microbes
play
crucial
role
in
modern
agriculture,
serving
as
biopesticides,
biostimulants/biofertilizers,
and
mitigating
abiotic
stress
crops.
Their
multifaceted
functions
contribute
significantly
to
crop
health
sustainability,
aligning
with
the
principles
of
regenerative
agriculture
by
minimizing
carbon
footprints
reducing
dependence
on
agrichemical
inputs.
The
concept
'microbial
consortia',
involving
combination
multiple
fungal
bacterial
species
or
strains,
has
gained
recognition
for
its
potential
advantages
over
single
species/strains
applications.
This
method
aims
employ
a
spectrum
ecological
functions,
encouraging
biological
equilibrium
within
agricultural
systems.
Recent
research
highlights
how
microbial
consortia
can
directly
indirectly
enhance
plant
health,
through
various
mechanisms
interactions
their
host
plants.
review
presents
examples
demonstrating
efficacy
biopesticides
biostimulants/biofertilizers.
These
exhibit
managing
diseases
pests,
while
also
promoting
growth
specific
biotic
stresses
examines
real-world
considering
instances
success
failure,
discusses
methodologies
employed
evaluating
interactions,
addresses
challenges
selection,
production,
application
optimal
use
providing
valuable
insights
current
future
prospects
agriculture.
International Journal of Molecular Sciences,
Год журнала:
2024,
Номер
25(6), С. 3340 - 3340
Опубликована: Март 15, 2024
Psychiatric
disorders
represent
a
primary
source
of
disability
worldwide,
manifesting
as
disturbances
in
individuals’
cognitive
processes,
emotional
regulation,
and
behavioral
patterns.
In
the
quest
to
discover
novel
therapies
expand
boundaries
neuropharmacology,
studies
from
field
have
highlighted
gut
microbiota’s
role
modulating
these
disorders.
These
alterations
may
influence
brain’s
processes
through
brain–gut
axis,
multifaceted
bidirectional
system
that
establishes
connection
between
enteric
central
nervous
systems.
Thus,
probiotic
prebiotic
supplements
are
meant
overall
health
play
an
insightful
alleviating
psychiatric
symptoms,
such
templates
major
depressive
disorder,
anxiety,
or
schizophrenia.
Moreover,
administration
psychotropic
drugs
has
been
revealed
induce
specific
changes
microbiome’s
diversity,
suggesting
their
potential
utility
combating
bacterial
infections.
This
review
emphasizes
intricate
correlations
microbiota,
mentioning
promising
approaches
regard
modulation
treatments,
well
antimicrobial
effects
medication.
