Naunyn-Schmiedeberg s Archives of Pharmacology, Год журнала: 2024, Номер 397(9), С. 6459 - 6505
Опубликована: Май 3, 2024
Язык: Английский
Life Sciences, Год журнала: 2024, Номер 352, С. 122899 - 122899
Опубликована: Июль 9, 2024
This comprehensive review provides an in-depth analysis of how nanotechnology has revolutionized cancer theragnostic, which combines diagnostic and therapeutic methods to customize treatment. The study examines the unique attributes, uses, difficulties linked different types nanoparticles, including gold, iron oxide, silica, Quantum dots, Carbon nanotubes, liposomes, in context In addition, paper progression nanotheranostics, emphasizing its uses precise medication administration, photothermal therapy, sophisticated such as MRI, CT, fluorescence imaging. Moreover, article highlights capacity nanoparticles improve effectiveness drugs, reduce overall toxicity body, open up new possibilities for treating by releasing drugs a controlled manner targeting specific areas. Furthermore, it tackles concerns regarding compatibility their potential harmful effects, significance continuous nanotherapeutic use medical treatments. finishes outlining future applications predictive oncology customized medicine.
Язык: Английский
Процитировано
60
Coordination Chemistry Reviews, Год журнала: 2024, Номер 507, С. 215750 - 215750
Опубликована: Фев. 29, 2024
Язык: Английский
Процитировано
42
Pharmaceutics, Год журнала: 2024, Номер 16(2), С. 223 - 223
Опубликована: Фев. 4, 2024
Niosomes are vesicular nanocarriers, biodegradable, relatively non-toxic, stable, and inexpensive, that provide an alternative for lipid-solid carriers (e.g., liposomes). may resolve issues related to the instability, fast degradation, bioavailability, insolubility of different drugs or natural compounds. can be very efficient potential systems specific delivery anticancer, antioxidant, anti-inflammatory, antimicrobial, antibacterial molecules. This review aims present overview their composition, most common formulation techniques, as well recent utilizations in cancer therapy.
Язык: Английский
Процитировано
31
Journal of Nanobiotechnology, Год журнала: 2024, Номер 22(1)
Опубликована: Ноя. 15, 2024
Abstract Nanotechnology holds immense promise in revolutionising healthcare, offering unprecedented opportunities diagnostics, drug delivery, cancer therapy, and combating infectious diseases. This review explores the multifaceted landscape of nanotechnology healthcare while addressing critical aspects safety environmental risks associated with its widespread application. Beginning an introduction to integration we first delved into categorisation various materials employed, setting stage for a comprehensive understanding potential. We then proceeded elucidate diverse applications nanotechnology, spanning medical tissue engineering, targeted gene development antimicrobial agents. The discussion extended current situation surrounding clinical translation commercialisation these cutting-edge technologies, focusing on nanotechnology-based products that have been approved globally date. also discussed considerations nanomaterials, both terms human health impact. presented vivo nanomaterial exposure, relation transport mechanisms, oxidative stress, physical interactions. Moreover, highlighted risks, acknowledging potential implications ecosystems biodiversity. Lastly, strived offer insights regulatory governing across different regions globally. By synthesising perspectives, underscore imperative balancing innovation stewardship, charting path forward responsible healthcare. Graphical abstract
Язык: Английский
Процитировано
26
Nano-Structures & Nano-Objects, Год журнала: 2024, Номер 39, С. 101299 - 101299
Опубликована: Авг. 23, 2024
Язык: Английский
Процитировано
17
Applied Surface Science Advances, Год журнала: 2024, Номер 21, С. 100605 - 100605
Опубликована: Апрель 30, 2024
The article discusses the function of green nanoparticles in preventing corrosion different alloys such as copper, zinc, steel, and aluminium alloys. Green are characterized by their environmentally friendly sustainable production methods, which emphasize using natural materials. Environmental issues have long been linked to traditional inhibitors, has led a shift towards more alternatives. A potential remedy for these is use nanoparticles, derived from renewable biodegradable resources. support sustainability goals strong inhibition properties. Their combined role makes them essential players future where environmental awareness material safety coexist. review envisages significant paradigm critical industrial contexts, calls robust ecologically approach prevention. can potentially transform field materials protection entirely, investigation inhibitors opens up new directions study development. In conclusion, this highlights crucial creating creative solutions will enhance productivity well-being. Finally, prospects difficulties sustainably applying also explored.
Язык: Английский
Процитировано
16
Deleted Journal, Год журнала: 2025, Номер 2(2)
Опубликована: Янв. 13, 2025
This review examines the potential of nanomaterials in revolutionizing food packaging, focusing on their role enhancing barrier properties and extending shelf life packaged foods. Traditional packaging materials often fall short effectively protecting against oxygen, moisture, UV light, resulting diminished quality shorter life. Nanomaterials, including nanoclays, metal oxide nanoparticles (e.g., ZnO, TiO₂), carbon-based graphene, carbon nanotubes), biodegradable options like cellulose nanocrystals, have emerged as promising solutions. These offer exceptional gas moisture properties, antimicrobial effects, protection capabilities. The provides an in-depth exploration various nanomaterials, highlighting distinctive mechanisms; such tortuosity which enhance performance by limiting permeability. It also discusses recent advancements integrating into both flexible rigid systems, well active intelligent that employs nanosensors for real-time monitoring freshness spoilage. Despite potential, challenges toxicity concerns, environmental impacts, economic constraints to large-scale adoption are addressed. emphasizes need future research dual-function can simultaneously improve enable sensing. innovations could transform technologies, promoting enhanced safety sustainability.
Язык: Английский
Процитировано
6
Molecular Cancer, Год журнала: 2025, Номер 24(1)
Опубликована: Янв. 18, 2025
Clinically, multimodal therapies are adopted worldwide for the management of cancer, which continues to be a leading cause death. In recent years, immunotherapy has firmly established itself as new paradigm in cancer care that activates body's immune defense cope with cancer. Immunotherapy resulted significant breakthroughs treatment stubborn tumors, dramatically improving clinical outcome patients. Multiple forms immunotherapy, including checkpoint inhibitors (ICIs), adoptive cell therapy and vaccines, have become widely available. However, effectiveness these immunotherapies is not much satisfying. Many patients do respond disease recurrence appears unavoidable because rapidly evolving resistance. Moreover, can give rise severe off-target immune-related adverse events. Strategies remove hindrances mainly focus on development combinatorial or exploitation novel immunotherapeutic mediations. Nanomaterials carrying anticancer agents target site considered practical approaches treatment. Nanomedicine combined offers possibility potentiate systemic antitumor immunity facilitate selective cytotoxicity against cells an effective safe manner. A myriad nano-enabled currently under investigation. Owing gaps between preclinical studies, nano-immunotherapy faces multiple challenges, biosafety nanomaterials trial design. this review, we provide overview summarize evidence indicating how nanomedicine-based increase efficacy immunotherapies. We also discuss key challenges emerged era nanotechnology-based immunotherapy. Taken together, combination drawing increasing attention, it anticipated will achieve desired success therapy.
Язык: Английский
Процитировано
5
Sustainability, Год журнала: 2025, Номер 17(3), С. 1250 - 1250
Опубликована: Фев. 4, 2025
Nanoparticle technology has emerged as a fundamental component across various industries, including electronics, renewable energy, textiles, and medical biotechnology, particularly for targeted drug delivery applications. Commercialization profoundly impacted economic growth, especially in the pharmaceutical electronics industries. Moreover, it improved workforce education training, generating millions of employment prospects associated with nanotechnology development. By 2024, Organisation Economic Co-operation Development anticipates that global market products will attain value United States Dollar (USD) 1 trillion to USD 3 trillion, resulting creation over 2 million new employments globally. The swift progression nanoparticle from 2000 2024 is primarily propelled by substantial industrial investment research development, alongside collaborations academic institutions. National Nanotechnology Initiative (US) significantly contributed these developments, federal funding exceeding 30 billion since its establishment 2001. This catalyzed significant advancements both commercial applications nanotechnology. Patent data highlights this expansion, China establishing itself preeminent nation patents. From steadily raised proportion patents, accounting almost 40% total 2024. US, Japan, Germany, Republic Korea continued be contributors, together advancing frontiers innovation In timeframe, quantity nanotechnology-related patents increased more than 150%, demonstrating growth sector. regulation US managed Food Drug Administration, about healthcare biotechnology As scope uses expanded, there an increasing demand extensive regulations concerning potential long-term environmental health effects. future trajectory nanotechnology, worldwide, hinge on continuous invention, advancement, governmental policy. upholding robust regulatory framework promoting ongoing collaboration between academics industry, complete societal progress can actualized.
Язык: Английский
Процитировано
3
Pharmaceutics, Год журнала: 2025, Номер 17(2), С. 180 - 180
Опубликована: Фев. 1, 2025
Background/Objectives: Numerous diseases such as diabetes, Alzheimer’s disease, and cancer have spread in the whole world, especially Arab world. Also, various applications of Schiff-base functionalized nanoparticles copper oxide (CuO-NPs) therapeutic been discovered. Thus, current research highlights (i) synthesis produced with a Schiff base (SB) serving capping agent during their (ii) assessment vitro biological activities base-synthesized (SB-CuO-NPs) (SB). Methods: SB-CuO-NPs were characterized using ultraviolet-visible (UV-Vis) spectroscopy, zeta potential, DLS analysis, transmission electron microscope (TEM). It also focuses on assessing activities, including antioxidant, scavenging, anti-diabetic, anti-Alzheimer, anti-arthritic, anti-inflammatory, cytotoxic enzymes inhibitory methods described literature. Results: The results compared those SB. demonstrated superior when to SB from which they produced. Conclusions: this investigation concluded that CuO-NPs, synthesized an alternative agent, exhibited enhanced efficacy relative original In future, efficiency against Alzheimer’s, will be assessed experimental animals (in vivo).
Язык: Английский
Процитировано
2