Agriculture,
Год журнала:
2024,
Номер
14(12), С. 2261 - 2261
Опубликована: Дек. 10, 2024
Avian
diseases,
especially
coccidiosis,
represent
a
significant
threat
to
poultry
production,
demanding
research
into
the
use
of
herbal
supplements
in
birds’
diets.
So,
aim
this
study
was
assess
efficacy
selected
components
mitigating
coccidiosis
broilers
and
examine
their
overall
impact
on
productivity
traits
broilers.
A
35-day
feeding
trial
conducted
with
1200
male
ROSS
308
broiler
chickens
two
facilities,
one
non-infected,
using
either
usual
coccidiostats
(UC−)
or
500
g/t
additive
(consisting
Holarrhena
antidysenterica,
Ficus
religiosa,
Berberis
aristata,
Allium
sativum,
Embelia
ribes,
Azadirachta
indica;
HA−)
other
intentionally
exposed
Eimeria
via
drinking
water
at
7
days
old,
corresponding
control
experimental
groups
(UC+
HA+).
Dietary
interventions
significantly
influenced
chicken
body
weight
(BW)
average
daily
gain
(ADG)
throughout
trial,
notably
day
21,
UC+
treatment
yielding
highest
values.
Herbal
did
not
affect
feed
conversion
ratio
(FCR)
liveability.
Under
infection,
litter
dry
matter
(DM)
content
differences
were
notable
14
favouring
treatments
(HA−
also
impacted
presence
duodenum
jejunum
between
treatments.
Despite
several
limitations,
reveals
that
additions
may
effectively
manage
infection
enhance
quality
since
demonstrated
improved
development
anatomy.
BACKGROUND
Legacy
media
are
publications
that
existed
before
the
internet.
Many
of
these
have
migrated
to
a
web
format,
either
replacing
or
in
parallel
their
print
issues.
Readers
place
an
economic
value
on
access
information
presented
as
they
pay
for
subscriptions
and
higher
degree
trust
content.
Much
has
been
written
about
inaccurate
misleading
health
social
media;
however,
content
accuracy
contained
legacy
not
examined
detail.
Discussion
herbs,
spices,
other
botanicals
absent
from
this
context.
OBJECTIVE
The
objectives
study
were
(1)
identify
associations
botanical
products
mentioned
targeted
range
demographic
groups
(2)
evaluate
against
published
scientific
studies.
METHODS
In
total,
10
popular
magazines
targeting
gender,
race/ethnicity,
sexual
orientation
selected
analysis.
Relevant
was
extracted
coded
over
1
year.
Associations
between
specific
factors
identified.
For
most
frequent
botanical–health
application
associations,
PubMed
search
conducted
reviews
corresponding
each
item’s
indicated
applications.
Where
no
systematic
available,
single
research
studies
sought.
RESULTS
A
total
237
unique
There
128
mentions
issues
1215
websites.
18
applications
identified
used
categorize
uses
various
individually
general
categories.
frequently
skin
care,
with
913
mentions,
immunity
enhancement,
705
gastrointestinal
probiotics,
184
cognitive
function
(stress
mental
health),
106
mentions.
Comparison
literature
evaluating
efficacy
functions
positive
support
aloe
vera,
argan
oil,
chamomile,
jojoba
lavender,
rosemary,
tea
tree
oil
care.
Berries,
ginger,
turmeric,
green
had
strongest
evidence
role
enhancement.
Ginger
oats
supported
having
health.
Finally,
berries,
ashwagandha,
cannabidiol
managing
stress.
Other
items
such
mushrooms
less
strongly
supported.
CONCLUSIONS
prevalent
indicates
that,
overall,
consistent
current
reports
products.
While
some
greater
than
others,
truly
egregious
falsehoods
absent.
Therefore,
may
be
considered
credible
source
readers
topics.
PLoS Pathogens,
Год журнала:
2024,
Номер
20(12), С. e1012816 - e1012816
Опубликована: Дек. 30, 2024
Chikungunya
virus
(CHIKV)
is
a
mosquito-transmitted
alphavirus
causing
fever,
myalgia,
and
debilitating
joint
swelling
pain,
which
in
many
patients
becomes
chronic.
The
frequent
epidemics
of
CHIKV
across
the
world
pose
significant
public
health
burden
necessitating
development
effective
antiviral
therapeutics.
A
cellular
imaging-based
high-content
screening
natural
compounds
identified
withaferin
(WFA),
steroidal
lactone
isolated
from
plant
Withania
somnifera,
as
potent
against
CHIKV.
In
ERMS
cells,
WFA
inhibited
replication
early
during
life
cycle
by
binding
non-structural
protein
nsP2
inhibiting
its
protease
activity.
This
viral
polyprotein
processing
minus-sense
RNA
synthesis.
mounted
inhibitory
activity
through
oxidising
property
reducing
agents
N-acetylcysteine
Glutathione-monoethyl
ester
effectively
reversed
WFA-mediated
inhibition
vitro
abolished
cultured
cells.
C57BL/6
mouse
model
chikungunya
disease,
resulting
significantly
lower
viremia.
Importantly,
CHIKV-infected
mice
showed
was
not
seen
WFA-treated
mice.
These
data
demonstrate
potential
novel
antiviral.
The North African Journal of Food and Nutrition Research,
Год журнала:
2024,
Номер
8(18), С. 253 - 261
Опубликована: Дек. 5, 2024
Background:
Combinatory
therapy
involving
medicinal
plants
utilizes
blends
of
different
species
to
enhance
therapeutic
efficacy,
increase
potency,
and
minimize
adverse
effects.
This
approach
leverages
the
synergistic
interactions
plant-derived
bioactive
compounds,
offering
a
natural
holistic
strategy
for
addressing
various
health
conditions.
Aims:
study
aimed
evaluate
effects
traditional
Algerian
combination
date
fruit
(Phoenix
dactylifera)
fenugreek
seeds
(Trigonella
foenum-graecum)
on
phagocytic
activity
hepatic
glutathione
(GSH)
levels.
Materials
Methods:
Phagocytic
was
measured
using
carbon
clearance
rate
test,
while
levels
were
determined
spectrophotometrically
from
liver
homogenates.
Results:
The
results
demonstrated
that
both
GSH
significantly
enhanced
in
animals
treated
with
plant
(p
<
0.001).
faster
mice
receiving
combined
treatment
(FG
“Fenugreek”
/
PD
“Phoenix
dactylifera”:
14.66
±
4.143)
compared
NaCl
control
group
(49.77
16.98).
Additionally,
index
higher
FG
(7.128
0.823)
groups
either
alone
(FG:
4.082
0.306)
or
(PD:
4.87
0.608).
Hepatic
also
elevated
other
=
0.040).
Conclusions:
exhibits
synergic
effect,
enhancing
immune
system
antioxidant
capacity.
These
findings
suggest
its
potential
development
novel,
naturally
derived
agents.
Keywords:
activity,
fruit,
seeds,
GSH,
therapy.
Journal of Herbmed Pharmacology,
Год журнала:
2024,
Номер
14(1), С. 112 - 119
Опубликована: Дек. 25, 2024
Introduction:
Natural
products
are
a
rich
source
of
antioxidants,
effective
on
immunological
disorders.
The
present
study
was
planned
to
evaluate
the
antioxidant
activity
ethanolic
extract
root
bark
an
Indian
medicinal
plant,
Eugenia
jambolana,
by
in
vitro
methods
and
immunomodulatory
vivo
methods.
Methods:
collected
E.
jambolana
(EJE)
prepared
tested
for
using
concentrations
10-50
µg/mL
through
2,2-diphenyl-1-picrylhydrazyl
(DPPH)
free
radical
superoxide
anion
scavenging
assays.
Further,
effects
EJE
were
assessed
animal
studies
against
experimental
antigen,
sheep
RBC,
oral
administration
at
doses
100,
200,
400
mg/kg,
measuring
its
impact
antibody
titer
values
antigen-antibody
reaction
paw
thickness
mice
(delayed-type
hypersensitivity
[DTH]
study)
humoral
cell-mediated
immune
responses,
respectively.
Results:
exhibited
properties
DPPH
radicals
with
IC50
43.79
±
0.24
47.64
0.18
respective
studies.
mg/kg
dose
demonstrated
significant
(P<0.05)
value
DTH
response
These
showed
that
produced
29.36%
39.06%
immunity
studies,
Conclusion:
experiments
this
potential
bark.
Agriculture,
Год журнала:
2024,
Номер
14(12), С. 2261 - 2261
Опубликована: Дек. 10, 2024
Avian
diseases,
especially
coccidiosis,
represent
a
significant
threat
to
poultry
production,
demanding
research
into
the
use
of
herbal
supplements
in
birds’
diets.
So,
aim
this
study
was
assess
efficacy
selected
components
mitigating
coccidiosis
broilers
and
examine
their
overall
impact
on
productivity
traits
broilers.
A
35-day
feeding
trial
conducted
with
1200
male
ROSS
308
broiler
chickens
two
facilities,
one
non-infected,
using
either
usual
coccidiostats
(UC−)
or
500
g/t
additive
(consisting
Holarrhena
antidysenterica,
Ficus
religiosa,
Berberis
aristata,
Allium
sativum,
Embelia
ribes,
Azadirachta
indica;
HA−)
other
intentionally
exposed
Eimeria
via
drinking
water
at
7
days
old,
corresponding
control
experimental
groups
(UC+
HA+).
Dietary
interventions
significantly
influenced
chicken
body
weight
(BW)
average
daily
gain
(ADG)
throughout
trial,
notably
day
21,
UC+
treatment
yielding
highest
values.
Herbal
did
not
affect
feed
conversion
ratio
(FCR)
liveability.
Under
infection,
litter
dry
matter
(DM)
content
differences
were
notable
14
favouring
treatments
(HA−
also
impacted
presence
duodenum
jejunum
between
treatments.
Despite
several
limitations,
reveals
that
additions
may
effectively
manage
infection
enhance
quality
since
demonstrated
improved
development
anatomy.