Optimization of Microwave-Assisted Extraction of Phenolic Compounds from Opuntia ficus-indica Cladodes DOI Open Access

Amira Oufighou,

Fatiha Brahmi, Sabiha Achat

и другие.

Processes, Год журнала: 2025, Номер 13(3), С. 724 - 724

Опубликована: Март 3, 2025

Background: Opuntia ficus-indica (OFI) cladodes are valuable and underestimated by-products that provide significant amounts of biologically active compounds. In this paper, microwave-assisted extraction (MAE) was performed for the recovery phenolic compounds from OFI using two approaches: response surface methodology (RSM) artificial neural network–genetic algorithm (ANN-GA), which were then compared following statistical indicators. Materials Methods: Four independent factors employed in optimization process (solvent concentration, microwave power, irradiation time, solid-to-liquid ratio) by selecting total content (TPC), estimated Folin–Ciocalteu method, as a response. The optimized extract tested antioxidant capacity reagent, Trolox Equivalent Antioxidant Capacity (TEAC), oxygen radical absorbance (ORAC) assays antimicrobial activity against 16 pathogenic strains agar well diffusion method. Results: maximum TPC values predicted with maximizing desirability function RSM 2177.01 mg GAE/100 g DW 1827.38 ANN. Both models presented certain advantages could be considered reliable tools predictability accuracy purposes. Using these conditions, high FCR assay (13.43 ± 0.62 GAE/g DW), TEAC (10.18 0.47 µmol TE/g ORAC (205.47 19.23 DW). pronounced only respect to S. aureus alimentarius, Streptococcus, E. coli, P. aeruginosa, A. flavus. Conclusions: This study underlines effectiveness approaches providing bioactive formulate food pharmaceutical products functional qualities.

Язык: Английский

Optimization of Microwave-Assisted Extraction of Phenolic Compounds from Opuntia ficus-indica Cladodes DOI Open Access

Amira Oufighou,

Fatiha Brahmi, Sabiha Achat

и другие.

Processes, Год журнала: 2025, Номер 13(3), С. 724 - 724

Опубликована: Март 3, 2025

Background: Opuntia ficus-indica (OFI) cladodes are valuable and underestimated by-products that provide significant amounts of biologically active compounds. In this paper, microwave-assisted extraction (MAE) was performed for the recovery phenolic compounds from OFI using two approaches: response surface methodology (RSM) artificial neural network–genetic algorithm (ANN-GA), which were then compared following statistical indicators. Materials Methods: Four independent factors employed in optimization process (solvent concentration, microwave power, irradiation time, solid-to-liquid ratio) by selecting total content (TPC), estimated Folin–Ciocalteu method, as a response. The optimized extract tested antioxidant capacity reagent, Trolox Equivalent Antioxidant Capacity (TEAC), oxygen radical absorbance (ORAC) assays antimicrobial activity against 16 pathogenic strains agar well diffusion method. Results: maximum TPC values predicted with maximizing desirability function RSM 2177.01 mg GAE/100 g DW 1827.38 ANN. Both models presented certain advantages could be considered reliable tools predictability accuracy purposes. Using these conditions, high FCR assay (13.43 ± 0.62 GAE/g DW), TEAC (10.18 0.47 µmol TE/g ORAC (205.47 19.23 DW). pronounced only respect to S. aureus alimentarius, Streptococcus, E. coli, P. aeruginosa, A. flavus. Conclusions: This study underlines effectiveness approaches providing bioactive formulate food pharmaceutical products functional qualities.

Язык: Английский

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