Chinese Journal of Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Март 5, 2025

Comprehensive Summary A divergent synthesis of spiroindenes through a palladium catalyzed cycloaddition between zwitterionic π‐propargyl species and benzofulvenes in moderate to good yields has been disclosed along with functional group compatibility broad substrate universality. This protocol features highly regioselective switchable process [3+2] [4+2] cycloadditions controlled by phosphine ligands different bite angles. The reaction mechanism clarified mechanistic studies DFT calculations, rendering that the coordination modes substrates angle play critical roles product regioselectivity.

Язык: Английский