Future Journal of Pharmaceutical Sciences,
Год журнала:
2024,
Номер
10(1)
Опубликована: Фев. 22, 2024
Abstract
Background
Cancer
is
a
significant
global
health
issue,
resulting
from
uncontrolled
cell
division
leading
to
abnormal
or
tissue
growth.
Traditional
chemotherapeutic
techniques
have
investigated
wide
variety
of
pharmaceutically
active
molecules
despite
their
poor
bioavailability,
quick
renal
clearance,
inconsistent
distribution,
and
unavoidable
side
effects.
Green
synthesis,
unlike
chemical
methods,
prioritizes
eco-friendliness
cost-effectiveness.
Using
natural
sources
like
plant
extracts,
it
minimizes
environmental
impact,
reduces
costs,
aligns
with
sustainability
goals.
Operating
under
milder
conditions,
consumes
less
energy
compared
traditional
approaches.
synthesis
highly
promising
efficient
method
for
producing
nanoparticles
due
its
versatility
scalability.
Main
body
Nanotechnology
making
progress
in
cancer
treatment
because
nanoparticles'
tiny
size,
large
surface
area,
adaptability,
functionality,
as
well
potential
induce
apoptotic
pathways
fast
penetration
internalization
into
cells.
Biosynthesis
metallic
using
microbe
extracts
attracting
attention
replace
toxic
chemicals
phytochemicals
that
can
act
reducing,
capping,
stabilizing
agents
improve
biocompatibility,
antitumor,
antioxidant
properties.
This
review
focuses
on
biosynthesized
anticancer
effects
breast,
prostate,
skin,
cervical,
colorectal,
lung,
liver
cancer.
Conclusion
therapy
stands
at
the
forefront
innovative
sustainable
Despite
challenges,
ongoing
research
demonstrates
biosynthesis
revolutionize
nanomedicine,
emphasizing
need
continued
exploration
collaboration
this
rapidly
advancing
field.
Overall,
offers
comprehensive
understanding
most
recent
developments
future
applications
medicine.
Pharmaceuticals,
Год журнала:
2024,
Номер
17(3), С. 315 - 315
Опубликована: Фев. 28, 2024
Cancer
continues
to
pose
one
of
the
most
critical
challenges
in
global
healthcare.
Despite
wide
array
existing
cancer
drugs,
primary
obstacle
remains
selectively
targeting
and
eliminating
cells
while
minimizing
damage
healthy
ones,
thereby
reducing
treatment
side
effects.
The
revolutionary
approach
utilizing
nanomaterials
for
delivering
therapeutic
agents
has
significantly
enhanced
efficacy
safety
chemotherapeutic
drugs.
This
crucial
shift
is
attributed
unique
properties
nanomaterials,
enabling
nanocarriers
transport
tumor
sites
both
passive
active
modes,
drug
elimination
from
delivery
systems.
Furthermore,
these
can
be
designed
respond
internal
or
external
stimuli,
thus
facilitating
controlled
release.
However,
production
nanomedications
therapy
encounters
various
that
impede
progress
this
field.
review
aims
provide
a
comprehensive
overview
current
state
nanomedication
treatment.
It
explores
variety
focusing
on
their
are
overcoming
limitations
conventional
chemotherapy.
Additionally,
delves
into
functionalities
nanocarriers,
highlighting
significant
impact
evolution
nanomedicine.
also
critically
assesses
recent
advancements
systems,
covering
range
innovative
methodologies.
Finally,
succinctly
addresses
encountered
developing
nanomedications,
offering
insightful
perspectives
guide
future
research
International Journal of Nanomedicine,
Год журнала:
2024,
Номер
Volume 19, С. 12889 - 12937
Опубликована: Дек. 1, 2024
Abstract:
Over
the
last
decade,
biomedical
nanomaterials
have
garnered
significant
attention
due
to
their
remarkable
biological
properties
and
diverse
applications
in
biomedicine.
Metal
oxide
nanoparticles
(NPs)
are
particularly
notable
for
wide
range
of
medicinal
uses,
including
antibacterial,
anticancer,
biosensing,
cell
imaging,
drug/gene
delivery.
Among
these,
zinc
(ZnO)
NPs
stand
out
versatility
effectiveness.
Recently,
ZnO
become
a
primary
material
various
sectors,
such
as
pharmaceutical,
cosmetic,
antimicrobials,
construction,
textile,
automotive
industries.
can
generate
reactive
oxygen
species
induce
cellular
apoptosis,
thus
underpinning
potent
anticancer
antibacterial
properties.
To
meet
growing
demand,
numerous
synthetic
approaches
been
developed
produce
NPs.
However,
traditional
manufacturing
processes
often
involve
economic
environmental
costs,
prompting
search
more
sustainable
alternatives.
Intriguingly,
synthesis
methods
utilizing
plants,
plant
extracts,
or
microorganisms
emerged
ideal
producing
These
green
production
techniques
offer
medicinal,
economic,
environmental,
health
benefits.
This
review
highlights
latest
advancements
applications,
showcasing
potential
revolutionize
field
with
eco-friendly
cost-effective
solutions.
Keywords:
antimicrobial,
antioxidant,
synthesis,
nanomedicine,
nanoparticle,
Expert Opinion on Drug Delivery,
Год журнала:
2024,
Номер
unknown
Опубликована: Дек. 8, 2024
Applying
artificial
intelligence
(AI)
to
nanomedicine
has
greatly
increased
the
production
of
specially
engineered
nanoscale
materials
for
tailored
medicine,
marking
a
significant
advancement
in
healthcare.
With
use
AI,
researchers
can
search
through
massive
databases
and
find
nano-properties
that
support
range
therapeutic
objectives,
eventually
producing
safer,
customized
nanomaterials.
AI
analyzes
patient
data,
including
clinical
genetic
information,
predict
results
individualized
care
makes
recommendations
therapy
improvement.
Furthermore,
logically
creates
nanocarriers
give
precise
controlled
drug
release
patterns
optimize
advantages
minimize
undesirable
side
effects.
Even
though
lot
potential
nanomedicine,
there
are
still
issues
data
integration
techniques,
moral
dilemmas,
requirement
governmental
backing.
Future
developments
tools
multidisciplinary
cooperation
between
scientists
with
expertise
biological
sciences
nanoengineering
essential
nanomedicine.
Together,
these
disciplines
propel
advancements
precision
contributing
ultimate
objective—a
future
which
combine
provide
really
The
authors
this
editorial
encourage
call
on
scientists,
physicians,
legislators
acknowledge
its
transform
treatment.
Future Journal of Pharmaceutical Sciences,
Год журнала:
2024,
Номер
10(1)
Опубликована: Фев. 22, 2024
Abstract
Background
Cancer
is
a
significant
global
health
issue,
resulting
from
uncontrolled
cell
division
leading
to
abnormal
or
tissue
growth.
Traditional
chemotherapeutic
techniques
have
investigated
wide
variety
of
pharmaceutically
active
molecules
despite
their
poor
bioavailability,
quick
renal
clearance,
inconsistent
distribution,
and
unavoidable
side
effects.
Green
synthesis,
unlike
chemical
methods,
prioritizes
eco-friendliness
cost-effectiveness.
Using
natural
sources
like
plant
extracts,
it
minimizes
environmental
impact,
reduces
costs,
aligns
with
sustainability
goals.
Operating
under
milder
conditions,
consumes
less
energy
compared
traditional
approaches.
synthesis
highly
promising
efficient
method
for
producing
nanoparticles
due
its
versatility
scalability.
Main
body
Nanotechnology
making
progress
in
cancer
treatment
because
nanoparticles'
tiny
size,
large
surface
area,
adaptability,
functionality,
as
well
potential
induce
apoptotic
pathways
fast
penetration
internalization
into
cells.
Biosynthesis
metallic
using
microbe
extracts
attracting
attention
replace
toxic
chemicals
phytochemicals
that
can
act
reducing,
capping,
stabilizing
agents
improve
biocompatibility,
antitumor,
antioxidant
properties.
This
review
focuses
on
biosynthesized
anticancer
effects
breast,
prostate,
skin,
cervical,
colorectal,
lung,
liver
cancer.
Conclusion
therapy
stands
at
the
forefront
innovative
sustainable
Despite
challenges,
ongoing
research
demonstrates
biosynthesis
revolutionize
nanomedicine,
emphasizing
need
continued
exploration
collaboration
this
rapidly
advancing
field.
Overall,
offers
comprehensive
understanding
most
recent
developments
future
applications
medicine.
