Cell Lysis, labeling efficacy and biodistribution of intravenously administered Technetium-99 m labeled multifunctional zirconia nanoparticles in animal model DOI Creative Commons

Ifra Sanaullah,

Saira Riaz, Irfan Ullah Khan

и другие.

Arabian Journal of Chemistry, Год журнала: 2023, Номер 16(12), С. 105267 - 105267

Опубликована: Сен. 16, 2023

Nanoparticles, to be used in biomedical applications, have been the subject of extensive investigation recent years. Recently, zirconia and iron gained significant relevance field due their superior mechanical structural qualities as well numerous biological applications. In this research, Fe3O4-stabilized nanopowders are fabricated using a low-cost sol-gel approach. Iron oxide sol is added 1-10 wt. % increments 0.1M sol. The obtained crystallite size values match with previously reported for tetragonally stabilizing (t-zirconia) phase. Hardness approximately 1278 HV, along fracture toughness ∼ 24.48 MPa.m^(1/2) observed stable tetragonal zirconia. Results from cell lysis experiments indicate that synthesized nanoparticles potential combat cancerous cells. An encapsulation efficacy up 73% after 120-minute time period. Radio labeling techniques employed label as-synthesized Sodium Pertechnetate (Na99mTcO4) labeled radiopharmaceuticals, allowing biodistribution assessment. Multiple CT scans rabbits performed obtain accurate results evaluate survival. Studies show radiolabeled highly absorbed animals' bladders, making them promising choice tumor therapy. Various physical properties animals periodically examined administration nanoparticle-based injection several months, no abnormalities found. through these characterizations can future therapeutic agents drug carriers.

Язык: Английский

A review on plant extract mediated green synthesis of zinc oxide nanoparticles and their biomedical applications DOI Creative Commons
Mouhaned Y. Al-darwesh, Sattar S. Ibrahim,

Mohammed A. Mohammed

и другие.

Results in Chemistry, Год журнала: 2024, Номер 7, С. 101368 - 101368

Опубликована: Янв. 1, 2024

Zinc oxide nanoparticles (ZnO NPs) exhibit distinctive characteristics, making them highly sought-after in many sectors. Nevertheless, conventional techniques for producing ZnO-NPs are linked to environmental and health hazards due toxic substances. In this review, we study zinc synthesized from plant extracts their subsequent biomedical uses detail. Research shows that several different employed manufacturing ZnO nanoparticles. Leaves, fruits, seeds, roots, complete plants all included these extracts. Phytochemicals such as phenolic compounds, alkaloids, flavonoids, terpenoids a part of biological matrices. compounds show bioreduction mechanism, act stabilizing reducing agent. The attributes (NPs), including size, shape, crystallinity, may be altered by adjusting the extract variety, concentration, synthesis conditions. Consequently, formed display notable diversity physical chemical subsequently impacting functionality. manufactured using green methods extensive, beneficial effects antibacterial activity against various pathogens, anti-inflammatory possible anticancer activities. Nanoparticles have been integrated into wound dressings, used carriers medication delivery, utilized biosensing imaging applications. enhanced biocompatibility reduced toxicity green-processed techniques, comparison those made approaches, make very appealing use contexts. Moreover, paper examines mechanisms, explicitly focusing on involvement phytochemicals processes reduction stabilization. Additionally, emphasizes difficulties potential future directions optimizing processes, increasing capacity, facilitating therapeutic

Язык: Английский

Процитировано

70

Application of Fourier Transform Infrared (FTIR) Spectroscopy in Characterization of Green Synthesized Nanoparticles DOI Creative Commons
Sylwia Pasieczna‐Patkowska, Marcin Cichy, Jolanta Flieger

и другие.

Molecules, Год журнала: 2025, Номер 30(3), С. 684 - 684

Опубликована: Фев. 4, 2025

The fundamental principle of Fourier Transform Infrared (FTIR) spectroscopy is based on the vibration and rotation atoms, it has become a universal widely used spectral methodology for detection internal molecular structures in diverse range fields. A considerable number review articles pertaining to applications FTIR have been published recent years. Nevertheless, comprehensive summary application nanoparticles’ (NPs’) green synthesis yet be presented. In present paper, we propose series case studies that demonstrate analysis metal oxide NPs synthesized using processes. Furthermore, presented position functional group bands spectra are responsible reduction, capping stabilization NPs. this review, explore advantages limitations methodologies overcoming these challenges. We also potential solutions complex spectra. intended serve as compendium information researchers engaged field NPs, utilizing research tool.

Язык: Английский

Процитировано

6

Physicochemical and photocatalytic properties of biogenic ZnO and its chitosan nanocomposites for UV-protection and antibacterial activity on coated textiles DOI
Karthik Subramani,

Aran Incharoensakdi

International Journal of Biological Macromolecules, Год журнала: 2024, Номер 263, С. 130391 - 130391

Опубликована: Фев. 27, 2024

Язык: Английский

Процитировано

15

Honey mediated synthesis of zinc oxide nanoparticles, and evaluation of antimicrobial, antibiofilm activities against multidrug resistant clinical bacterial isolates DOI

Sudhakarachari Atapakala,

Siva Sankar Sana,

Balaji Kuppam

и другие.

Journal of Industrial and Engineering Chemistry, Год журнала: 2024, Номер 135, С. 110 - 121

Опубликована: Янв. 10, 2024

Язык: Английский

Процитировано

11

Bioactive ZnO Nanoparticles: Biosynthesis, Characterization and Potential Antimicrobial Applications DOI Creative Commons
Md. Amdadul Huq, Md. Aminul Islam Apu, Md. Ashrafudoulla

и другие.

Pharmaceutics, Год журнала: 2023, Номер 15(11), С. 2634 - 2634

Опубликована: Ноя. 16, 2023

In recent years, biosynthesized zinc oxide nanoparticles (ZnONPs) have gained tremendous attention because of their safe and non-toxic nature distinctive biomedical applications. A diverse range microbes (bacteria, fungi yeast) various parts (leaf, root, fruit, flower, peel, stem, etc.) plants been exploited for the facile, rapid, cost-effective synthesis ZnONPs. Plant extracts, microbial biomass or culture supernatant contain biomolecules including enzymes, amino acids, proteins, vitamins, alkaloids, flavonoids, etc., which serve as reducing, capping stabilizing agents during biosynthesis The ZnONPs are generally characterized using UV-VIS spectroscopy, TEM, SEM, EDX, XRD, FTIR, etc. Antibiotic resistance is a serious problem global public health. Due to mutation, shifting environmental circumstances excessive drug use, number multidrug-resistant pathogenic continuously rising. To solve this issue, novel, effective antimicrobial needed urgently. Biosynthesized could be novel powerful characteristics. It proven that strong activity against microorganisms bacteria. possible mechanisms generation reactive oxygen species, physical interactions, disruption cell walls membranes, damage DNA, enzyme inactivation, protein denaturation, ribosomal destabilization mitochondrial dysfunction. review, characterization reviewed comprehensively. Also, applications highlighted.

Язык: Английский

Процитировано

19

Ajwain honey loaded CeO2 nanocomposite for antioxidant, chemical sensors and photocatalysis studies DOI Creative Commons

M. Mylarappa,

C. Selvam,

K. S. Harisha

и другие.

Kuwait Journal of Science, Год журнала: 2023, Номер 51(1), С. 100145 - 100145

Опубликована: Ноя. 7, 2023

The present study used a simple reflux method to efficiently produce eco-friendly ajwain honey (AH) loaded cerium oxide (CeO2) nanoparticles. X-ray diffractometer (XRD), scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FT-IR), energy dispersive (EDAX), and UV–Visible methods were examine the materials. Using 2,2-diphenylpicrylhydrazyl (DPPH) free radical, developed AH/CeO2 demonstrates 81% radical scavenging activity with an IC50 value of 102.5 mg/mL. electrochemical was measured in 3 M KOH electrolyte solution using carbon pasted electrode. Electrochemical characteristics such as reversibility (ER), proton diffusion coefficient (D), specific capacitance (Csp) have been significantly enhanced. AH doped CeO2 electrode modification materials vital role boosting sensor detection sensitivity determination cow urine, Pb+2 Hg+2 ions. photocatalysis investigated utilizing water pollutants methyl violet (MV) Congo red (CR). MV pollutant is completely degraded (100%) after 60 min, CR around 82%, suggesting excellent performance CeO2.

Язык: Английский

Процитировано

16

Synthesis, characterization, and application of honey stabilized inulin nanoparticles as colon targeting drug delivery carrier DOI

Subin Joseph,

Mahima Jadav, Raghu Solanki

и другие.

International Journal of Biological Macromolecules, Год журнала: 2024, Номер 263, С. 130274 - 130274

Опубликована: Фев. 17, 2024

Язык: Английский

Процитировано

7

Unraveling the mysteries of silver nanoparticles: synthesis, characterization, antimicrobial effects and uptake translocation in plant—a review DOI Creative Commons
Ahmed Fares,

Abdou Mahdy,

Gamal Ahmed

и другие.

Planta, Год журнала: 2024, Номер 260(1)

Опубликована: Май 24, 2024

Abstract Main conclusion The study thoroughly investigates nanosilver production, properties, and interactions, shedding light on its multifaceted applications. It underscores the importance of characterizing for predicting behavior in complex environments. Particularly, it highlights agricultural environmental ramifications uptake by plants . Nowadays, silver nanoparticles (AgNPs) are a very adaptable nanomaterial with many uses, particularly antibacterial treatments operations. Clarification key elements nanosilver, such as synthesis characterization procedures, activity, intricate interactions plants, those pertaining to translocation mechanisms, is aim this in-depth investigation. Nanosilver process that includes range methodologies, including chemical, biological, sustainable approaches also environmentally benign. This section provides critical evaluation these methods, considering their impacts repeatability, scalability, impact. physicochemical properties were determined means procedures. review significance analytical spectroscopy, microscopy, other state-of the-art methods fully particles. Although grasp necessary order predict potential biological systems. second half article delves into have emphasizing mechanisms absorption translocation. There significant problems from subsequent passage through tissues. In summary, summarizing state-of-the-art information field, offers comprehensive overview characterization, capabilities, plants. paper contributes ongoing conversation nanotechnology. Graphical abstract

Язык: Английский

Процитировано

7

Recent advancements in sustainable synthesis of zinc oxide nanoparticles using various plant extracts for environmental remediation DOI
Sapana Jadoun, Jorge Yáñez, Radhamanohar Aepuru

и другие.

Environmental Science and Pollution Research, Год журнала: 2024, Номер 31(13), С. 19123 - 19147

Опубликована: Фев. 20, 2024

Язык: Английский

Процитировано

5

Phytogenic metal nanoparticles: A promising frontier in natural medicine for inflammation and wound repair DOI

Sweta Mishra,

Chandana Mohanty

Next research., Год журнала: 2025, Номер unknown, С. 100160 - 100160

Опубликована: Янв. 1, 2025

Язык: Английский

Процитировано

0